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TRADING UPDATES: Nuformix says NXP002 shows anti-inflammatory effect

Thu, 18th May 2023 14:31

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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Sareum Holdings PLC - Cambridge-based biotechnology company developing kinase inhibitors for autoimmune diseases and cancers - Commences a phase 1a clinical trial for its SDC-1801 treatment. Says patient recruitment is in progress at clinical units in Victoria, Australia. SDC-1801 is a potential therapeutic for a number of autoimmune diseases. Says application trial follows approval by the Human Research Ethics Committee, while the application has also been acknowledged by Australia's Therapeutic Goods Administration. Says phase 1b clinical study expected to begin in psoriasis patients in 2024.

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Nuformix PLC - London-based pharmaceutical development company targeting unmet medical needs in fibrosis and oncology via drug repurposing - Says study data indicates its NXP002 treatment alone delivers an anti-inflammatory effect, suppressing the release of inflammatory cytokines by over 90%. Adds that the treatment shows an addition anti-inflammatory effect when used with current standards of care. Says results suggest NXP002 increases efficacy of existing therapies with the benefit of inhaled delivery. Says anti-inflammatory takes only an hour to have an effect, and strong effect lasts for 12 hours, and anti-inflammatory effect is still present after 24 hours. "I'm absolutely delighted with the data we've generated over recent months - all the results we've achieved are as good as we could have hoped for and are the first results from advanced 'close to patient' IPF and inflammation human tissue disease models," comments Executive director Dan Gooding.

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Conygar Investment Co PLC - London-based property investor and developer - Says Nottingham City Council has approved its application for the next phase of The Island Quarter development. Says application includes 23,123 square metre bioscience building, including laboratory and office space. Chief Executive Robert Ware comments: "We are delighted that the next phase of development has been approved. Nottingham is already home to a large number of exciting businesses in the bioscience space and this scheme will be an excellent addition to the mixed-use development we are creating at The Island Quarter".

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Secure Trust Bank PLC - Solihull, England-based savings accounts and lending services provider - Says net lending in the first quarter of 2023 was GBP3.01 billion, up 17% from GBP2.57 billion a year ago. New business lending rose 7.2% to GBP523.5 million, from GBP488.2 million, which it says demonstrates sustained growth momentum, in spite of tightened lending criteria. Adds that its cost optimisation programme is on track to deliver GBP4 million in annualised savings by the end of 2023. "We see significant opportunity for sustainable growth in our focused market segments and are well positioned to help consumers and businesses fulfil their ambitions and to continue to grow our net lending and scale our business as we strengthen our distribution networks and relationships...Although the economic environment remains uncertain, we have started the year positively and are confident in delivering on our plans for the full year and our medium term targets," Chief Executive David McCreadie says.

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Artemis Resources Ltd - Perth-based based mining company, with gold, copper and cobalt projects in Australia - Says historical geology and a data review confirms that its 2020 drill programme intercepted gold mineralisation within a quartz diorite intrusion. Says drilling has defined the intrusion over 2 kilometres, with elevated gold in rock chips over a strike length of 4 kilometres. Says there may be a possible relationship with Sanukitoid granitoids identified by De Grey Mining in the Mallina basin. Adds that an induced polarisation survey will begin in May, in order to help identify sulphides at depth. Exploration Manager Luke Meter says: "We have a new understanding of the importance of intrusion related gold in the Pilbara, including the identification of Sanukitoid like intrusions by the GSWA in the vicinity of the Karratha Granodiorite, some 2.5 km from Lulu Creek. The significance of the historic gold mineralisation therefore becomes apparent. With the Lulu Creek reconnaissance drill holes displaying similar grade and scale to De Grey's Diucon deposits, the potential upside for Lulu Creek is appreciable."

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By Harvey Dorset, Alliance News reporter

Comments and questions to newsroom@alliancenews.com

Copyright 2023 Alliance News Ltd. All Rights Reserved.

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12 Mar 2024 14:30

UK shareholder meetings calendar - next 7 days

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Tuesday 19 March 
BlackRock Throgmorton Trust PLCAGM
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Eco Animal Health Group PLCGM re share buybacks
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Comments and questions to newsroom@alliancenews.com
  
A full 21-day events calendar is provided each day with a subscription to Alliance News UK Professional.
  
Copyright 2024 Alliance News Ltd. All Rights Reserved.

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1 Mar 2024 10:31

IN BRIEF: Nuformix announces subscription to raise GBP150,000

Nuformix PLC - London-based developer of treatments for fibrosis and oncology via drug repurposing - Announce intention to raise gross proceeds of GBP150,000 through a subscription for 75.0 million new shares at a price of 0.20 pence each. The shares will represent 9.2% of Nuformix's enlarged issued share capital. Company will use the subscription's net proceeds primarily to further advance its NXP002 programme for the inhaled treatment of idiopathic pulmonary fibrosis.

Read more
3 Jan 2024 10:16

IN BRIEF: Nuformix narrows annual loss as develops drug assets

Nuformix PLC - London-based developer of treatments for fibrosis and oncology via drug repurposing - Pretax loss narrows to GBP927,972 in 18 months that ended September 30 from GBP1.3 million in the 12 months that ended March 31, 2022, following its change of financial year-end. Has no meaningful revenue in either period, so reduced loss is due to lower administrative expenses.

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23 Oct 2023 12:38

Nuformix gets patent in Japan for pulmonary fibrosis treatment NXP002

(Alliance News) - Nuformix PLC on Monday said it has been issued with a patent in Japan for NXP002, its potential novel inhaled treatment for idiopathic pulmonary fibrosis.

Read more
18 Sep 2023 10:20

IN BRIEF: Nuformix to receive milestone payments from Oxilio pact

Nuformix PLC - London-based pharmaceutical development company targeting unmet medical needs in fibrosis and oncology - Says it will receive immediate and near-term milestone payments as part of an update to its NXP001 exclusive licensing agreement with Oxilio Ltd. Nuformix does not disclose any financial details on this. Under the revised agreement, says Oxilio will acquire ownership of Nuformix's NXP001 patent estate. Says it will receive the additional milestone payments while retaining further development milestones and royalties capped at GBP2 million per year.

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17 Aug 2023 15:43

UK shareholder meetings calendar - next 7 days

Friday 18 August 
Adams PLCAGM
ME Group International PLCGM re proposed share buyback
Oxford BioDynamics PLCGM re placing
Pathfinder Minerals PLCGM re disposal of the subsidiary
Monday 21 August 
Calculus VCT PLCAGM
Home REIT PLCGM re changes to the investment policy
Tuesday 22 August 
Cake Box Holdings PLCAGM
ReNeuron Group PLCAGM
RUA Life Sciences PLCAGM
Smoove PLCAGM
STM Group PLCAGM
Wednesday 23 August 
Brandshield Systems PLCAGM
James Latham PLCAGM
LifeSafe Holdings PLCGM re shareholder circular
Momentum Multi-Asset Value Trust PLCGM re appointment of the liquidators
Sovereign Metals LtdGM re share placement options
Thor Energy PLCGM re proposed share consolidation
Thursday 24 August 
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Concurrent Technologies PLCAGM
CyanConnode Holdings PLCAGM
Nuformix PLCAGM
Oryx International Growth Fund LtdAGM
ThomasLloyd Energy Impact Trust PLCAGM
ThomasLloyd Energy Impact Trust PLCGM re market purchases of its own ordinary shares
  
Copyright 2023 Alliance News Ltd. All Rights Reserved.

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22 May 2023 12:45

Nuformix loss narrows; near-term goal to focus on NXP002 asset

(Alliance News) - Nuformix PLC on Monday reported a narrowed annual loss as it made progress on optimising costs and furthering its lead asset, NXP002.

Read more
17 Apr 2023 12:14

Nuformix raises GBP70,000 to fund NXP002 programme

(Alliance News) - Nuformix PLC on Monday said it has raised GBP70,000 through a subscription for 35.0 million new shares at a price of 0.20 pence each.

Read more
27 Mar 2023 18:42

TRADING UPDATES: Sabien works with Empiric; Coro sells in Italy

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Monday and not separately reported by Alliance News:

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15 Feb 2023 12:12

Nuformix progresses NXP002 trial after acquiring human tissue

(Alliance News) - Nuformix PLC on Wednesday said that, despite having to wait longer than expected, human disease tissue has now been acquired for its NXP002 programme.

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13 Dec 2022 14:54

Nuformix interim loss virtually flat as continues work on drugs

(Alliance News) - Nuformix PLC on Tuesday reported a negligibly smaller half-year loss as it continued to work on treatments for cancer and fibrosis, a disease which scars tissues in the lungs.

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23 Sep 2022 21:02

TRADING UPDATES: Neometals swings to loss; Funding Circle strikes deal

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Friday and not separately reported by Alliance News:

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18 Aug 2022 16:01

UK shareholder meetings calendar - next 7 days

Friday 19 August 
Braemar Shipping Services PLCAGM
Citius Resources PLCAGM
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Volex PLCAGM
Monday 22 August 
African Pioneer PLCAGM
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Amur Minerals CorpGM subsidiary sale
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Copyright 2022 Alliance News Limited. All Rights Reserved.

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10 Aug 2022 11:14

IN BRIEF: Nuformix shares rise on tolerability studies completion

Nuformix PLC - London-based pharmaceutical firm targeting fibrosis and oncology - Says NXP002, a potential treatment for idiopathic pulmonary fibrosis, has successfully completed pre-clinical tolerability studies. "Tolerability has been demonstrated across a new range of doses, including higher doses than previously given," it explains. Work now commences to explore how the new doses studied can best optimise efficacy and the treatment's positive pharmacological profile.

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