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Pin to quick picksN4 Pharma Plc Share News (N4P)

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TRADING UPDATES: hVIVO wins contract; Dev Clever cancels shares

Tue, 17th Jan 2023 16:23

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Tuesday and not separately reported by Alliance News:

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Newbury Racecourse PLC - Newbury, England-based racing, entertainment and events company - In September, Newbury announced the launch of the Great Christmas Carnival at Newbury Racecourse in an agreement with Underbelly Ltd. Says the event was expected to create a new revenue stream, but now says event was not as well attended as expected, resulting in a material loss for both the company and Underbelly. Says its other core revenue streams during 2022 performed in line with its expectations and pre-Covid levels. Expects to "break even or make a small profit" in 2022. Plans to announce 2022 results in May.

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Hydrogen Utopia International PLC - London-based developer of mixed plastic waste-to-fuel technology - Intends to withdraw its shares from trading on the AQSE Main Market. Under AQSE rules, the company is required to give 20 business days' notice of its intention to withdraw from trading on AQSE. Expects trading to close on February 14.

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hVIVO PLC - London-based contract research organisation, formerly known as Open Orphan PLC - Consultancy services division Venn Life Sciences signs contract with a major global pharmaceutical client worth EUR3.2 million over two years. Contract begins in January 2023. The Venn division will provide clinical pharmacokinetics consultancy and programming services to the client. "Venn's outstanding expertise and reputation in the industry over the past 25 years makes them a go-to partner. In addition, for infectious disease products, hVIVO and Venn have also been able to conduct projects from discovery to Phase II Challenge Studies, something no one else can offer," says Chief Executive Yamin Khan.

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Ecora Resources PLC - London-based natural resources royalty company - Says saleable production from Kestrel mine during the fourth quarter of 2022 was impacted by reduced mining rates and operational constraints that limited throughput volumes at the handling and preparation plant. Expects this to continue into 2023. The average price for product sold from its private royalty area during the period of around USD280 per tonne was in line with the quarterly average market price, resulting in royalty income for quarter four of around USD10 million. However, says strong pricing throughout 2022 resulted in a record Kestrel contribution of USD107 million, versus USD48 million in 2021. Plans to publish a full quarter four trading update on January 31.

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Image Scan Holdings PLC - Leicestershire, England-based X-ray screening systems supplier - Notes first sale of new product, with sale of two units of ThreatScan-AS1 Portable X-Ray system in Africa. Says customer is an African Explosive Ordnance Disposal unit, and the system has been supplied for use in counter EOD operations. Chief Executive Vincent Deery says: "Whilst we have been supplying our systems to EOD agencies all over the world for many years, this is the first sale of our recently released highest performing fully integrated system into the market."

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Avacta Group PLC - Cambridge, England-based drug developer and diagnostics company - Says AVA6000 continues to show a "very favourable safety profile" in the fourth dose cohort of the ALS-6000-101 dose escalation phase 1 clinical trial. AVA6000 is a form of the chemotherapy drug doxorubicin, which slows or stops the growth of cancer cells by blocking an enzyme called topo isomerase 2.19 patients with a range of advanced and/or metastatic solid tumours enrolled across four cohorts, have been administered AVA6000 to date.

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N4 Pharma PLC - Derby, England-based pharmaceutical company focused on developing Nuvec, a delivery system for vaccines and cancer treatments - Completes two in vivo studies demonstrating that Nuvec loaded with OVA m-cherry DNA and encapsulated within an acid protective polymer can be dosed orally, penetrate the mucus layer and successfully express the OVA m-cherry locally in the intestine epithelial cells. "These studies are at an early stage in the development of an oral application, but show the versatility of Nuvec both in terms of its ease of formulation and application in a wide number of areas. Having successfully demonstrated Nuvec can be administered orally and locally transfect cells in the intestine, the next step is to investigate what the most suitable medical application might be for this delivery method," says Chief Executive Nigel Theobald.

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Dev Clever Holdings PLC - Software developer for immersive learning and career guidance - Cancels listing of its shares on London Stock Exchange. Says Tuesday is the last day of the company's listing. Following cancellation, management will complete a rebranding of the company and its subsidiaries under the "Veative" banner. Its name will change to Veative Group PLC.

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By Sophie Rose, Alliance News reporter

Comments and questions to newsroom@alliancenews.com

Copyright 2023 Alliance News Ltd. All Rights Reserved.

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19 Jan 2024 13:00

N4 Pharma's Nuvec granted patent in India

(Sharecast News) - N4 Pharma, a pharmaceutical company developing the cancer vaccine delivery system Nuvec, announced on Friday that it has received confirmation from the University of Queensland regarding the granting of its patent for Nuvec in India.

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19 Jan 2024 09:26

IN BRIEF: N4 Pharma gets India patent for medical delivery system

N4 Pharma PLC - Derbyshire, England-based pharmaceutical company, focused on the development of Nuvec - University of Queensland has informed the company that it has been notified by its Indian patent attorney of the granting of its patent for Nuvec in India. Nuvec is a novel silica nanoparticle delivery system for cancer treatments, gene therapy and vaccines. N4 Pharma says the granted patent in India is for a composition of matter patent for the particle itself, alongside the manufacturing process relating to how the particle is made. Says it matches the patents granted in the US, Canada, Europe, Japan, Australia and China.

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16 Jan 2024 14:05

N4 Pharma subsidiary agrees work programme for glaucoma treatment

(Sharecast News) - N4 Pharma announced a significant development through its subsidiary Nanogenics on Tuesday, after Nanogenics inked a contract to initiate the formulation and sequence selection work for its ECP105 product, aimed at pre-clinical studies at King's College, London.

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IN BRIEF: N4 Pharma touts contract to test glaucoma treatment, ECP105

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N4 Pharma reports progress in Nuvec clinical research

(Sharecast News) - Pharmaceutical delivery system developer N4 Pharma reported significant progress in its research efforts to enhance viral vector performance using Nuvec on Monday.

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N4 Pharma hails increased efficacy of Nuvec when complexed with AAV8

(Alliance News) - N4 Pharma PLC on Monday said that a series of experiments have shown that Nuvec can deliver increased transduction efficacy, when complexed with Adeno-Associated virus 8.

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(Alliance News) - Stock prices in London closed higher on Monday, after investors shrugged off hawkish comments from US Federal Reserve officials amid festive cheer.

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N4 Pharma rises on successful results from Nuvec administration

(Alliance News) - N4 Pharma PLC on Monday announced the successful oral administration of Nuvec with a DNA plasmid after receiving promising results from its research programme with the University of Queensland.

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N4 Pharma upbeat on recent Nuvec developments

(Sharecast News) - N4 Pharma updated the market on Monday on its ongoing research efforts related to Nuvec, its delivery system designed for cancer treatments and vaccines.

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