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Pin to quick picksAvacta Group Share News (AVCT)

Share Price Information for Avacta Group (AVCT)

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Share Price: 46.50
Bid: 46.00
Ask: 47.00
Change: -0.25 (-0.53%)
Spread: 1.00 (2.174%)
Open: 45.75
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Avacta partners with Selexis ahead of first-in-human trials

Thu, 20th Jun 2019 10:28

(Sharecast News) - Avacta Group announced on Thursday that it has partnered with life sciences company Selexis to develop the Chinese hamster ovary (CHO) cell line, which will be used to manufacture Avacta's first 'Affimer' clinical candidate for first-time-in-human clinical trials.The AIM-traded firm said the "major milestone" would keep it on track to submit an IND/CTA application for an Affimer PD-L1 inhibitor by the end of 2020.It said its first clinical candidate would be against PD-L1 - a clinically-validated immune checkpoint that played an important role in the tumour escape mechanism in cancer.The lead molecule - AVA004 - was described by the company as a "potent" PD-L1 antagonist that had been engineered with an Fc domain for half-life extension.Avacta said it had demonstrated the preclinical efficacy of AVA004 in syngeneic and xenograft mouse models, explaining that it compared "favourably" to approved monoclonal antibodies such as 'Imfinzi', 'Tecentriq' and 'Bavencio' at the doses administered."The strategic partnership with Selexis allows Avacta to access the technology and know-how to develop high-expressing CHO cell lines as well as the extensive experience of developing a range of Fc fusion proteins for clinical manufacturing," said Avacta chief executive officer Alastair Smith."These cell lines are the essential basis of clinical manufacturing of AVA004 and this partnership supports Avacta's strategy to demonstrate safety and tolerability of the Affimer platform in humans with a planned IND/CTA by the end of 2020."Smith said the ultimate aim was to combine AVA004 with other Affimer checkpoint modulators in bispecific cancer immunotherapies, and with novel chemotherapies, as drug conjugates and combination therapies utilising proprietary tumour microenvironment targeting chemistry."These approaches seek to combine modulation of the adaptive immune response with stimulation of the innate immune system, with the aim of improving the clinical outcome for the sizeable proportion of solid tumour patients having 'cold' tumours that do not respond to checkpoint inhibitors alone."
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19 Jun 2023 10:16

Avacta denies press speculation over potential fundraising

(Sharecast News) - Oncology drug developer Avacta Group responded to recent market speculation over a potential fundraising initiative on Monday.

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19 Jun 2023 09:09

LONDON MARKET OPEN: Stocks falter amid weaker outlook for China

(Alliance News) - Stock prices in London opened lower on Monday, ahead of more interest rate decisions, and amid fears for China's slowing economic recovery.

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19 Jun 2023 07:53

LONDON BRIEFING: Severn Trent deal sized up by CMA; Coca-Cola HBC buys

(Alliance News) - Stocks in London are called lower on Monday, ahead of more central bank decisions, while a meeting between US Secretary of State Antony Blinken and his Chinese counterpart put relations between the two nations back under the spotlight.

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5 Jun 2023 12:28

Avacta triggers second milestone payment in AffyXell venture

(Sharecast News) - Life science company Avacta Group announced on Monday that a second milestone equity payment had been triggered, resulting in an increased shareholding for Avacta in AffyXell Therapeutics.

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5 Jun 2023 12:06

Avacta sees shares rise on new equity payment for South Korea venture

(Alliance News) - Avacta Group PLC on Monday celebrated "rapid" progress on its joint venture in South Korea, following a second equity payment.

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1 Jun 2023 14:53

Avacta buys Belgium-based Coris Bioconcept for £7.4m

(Sharecast News) - Life science company Avacta Group announced the acquisition of Coris Bioconcept for initial cash consideration of £7.4m on Thursday.

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1 Jun 2023 10:24

Avacta enhances rapid test portfolio with GBP7.4 million Coris buy

(Alliance News) - Avacta Group PLC on Thursday said that it has bought Coris Bioconcept SRL, adding a range of professional-use rapid tests to its product portfolio.

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27 Apr 2023 14:34

TRADING UPDATES: Volex wins contract; Engage XR revenue jumps

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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27 Apr 2023 12:11

Avacta doses first patient in US tumour treatment trial

(Sharecast News) - Oncology and diagnostics developer Avacta announced the dosing of the first patient in the United States under its investigational new drug (IND) application on Thursday - a milestone for its first therapeutic product 'AVA6000', based on its proprietary 'preCISION' technology.

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25 Apr 2023 14:39

EARNINGS SUMMARY: hVIVO sees 30% revenue growth; Next 15 lifts payout

(Alliance News) - The following is a round-up of earnings by London-listed companies, issued on Friday and not separately reported by Alliance News:

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25 Apr 2023 13:51

Revenue rises, adjusted EBITDA loss improves for Avacta

(Sharecast News) - Oncology-focussed drugs and diagnostics developer Avacta reported full-year revenue of £9.7m in its preliminary results on Tuesday, up from £2.9m year-on-year.

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18 Apr 2023 15:47

UK earnings, trading statements calendar - next 7 days

Wednesday 19 April 
Antofagasta PLCTrading Statement
discoverIE Group PLCTrading Statement
Distribution Finance Capital Holdings PLCFull Year Results
Hunting PLCTrading Statement
Just Eat Takeaway.com NVTrading Statement
Kainos Group PLCTrading Statement
Liontrust Asset Management PLCTrading Statement
M Winkworth PLCFull Year Results
Network International Holdings PLCTrading Statement
Thursday 20 April 
AJ Bell PLCTrading Statement
Arix Bioscience PLCFull Year Results
Centamin PLCTrading Statement
Deliveroo PLCTrading Statement
Dianomi PLCFull Year Results
Dunelm Group PLCQ3 Results
Foxtons Group PLCTrading Statement
GB Group PLCTrading Statement
Hochschild Mining PLCFull Year Results
Intelligent Ultrasound Group PLCFull Year Results
Oxford BioMedica PLCFull Year Results
PensionBee Group PLCTrading Statement
Rentokil Initial PLCTrading Statement
Rio Tinto PLCTrading Statement
Senior PLCTrading Statement
Segro PLCTrading Statement
WH Smith PLCHalf Year Results
Friday 21 April 
Angle PLCFull Year Results
BHP Group LtdTrading Statement
Lookers PLCFull Year Results
Monday 24 April 
Brighton Pier Group PLCFull Year Results
CentralNic Group PLCTrading Statement
Checkit PLCFull Year Results
Egdon Resources PLCHalf Year Results
Keystone Law Group PLCFull Year Results
Lok'n Store Group PLCHalf Year Results
Novacyt SAFull Year Results
Tuesday 25 April 
AB Dynamics PLCHalf Year Results
Anglo American PLCTrading Statement
Associated British Foods PLCHalf Year Results
Avacta Group PLCFull Year Results
Banco Santander SAQ1 Results
Card Factory PLCFull Year Results
Coca-Cola Europacific Partners PLCTrading Statement
Corero Network Security PLCFull Year Results
Dillistone Group PLCFull Year Results
Focusrite PLCHalf Year Results
IWG PLCTrading Statement
Jadestone Energy PLCFull Year Results
Next Fifteen Communications Group PLCFull Year Results
Northcoders Group PLCFull Year Results
Petrofac LtdFull Year Results
Quilter PLCTrading Statement
Resolute Mining LtdTrading Statement
RWS Holdings PLCTrading Statement
Travis Perkins PLCTrading Statement
WAG Payment Solutions PLCTrading Statement
Whitbread PLCFull Year Results
  
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17 Apr 2023 09:43

Avacta presents pre-clinical data for anti-cancer candidate

(Sharecast News) - Life science company Avacta Group announced the presentation of pre-clinical data for its novel 'preCISION' proteasome inhibitor AVA3996 on Monday.

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6 Apr 2023 12:14

Avacta opens first two clinical investigator sites in US for AVA6000

(Alliance News) - Avacta Group PLC on Thursday said it opened its first two clinical investigator sites for the phase 1 clinical trial of AVA6000 on Wednesday, under it US investigational new drug application.

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6 Apr 2023 10:09

Avacta opens first US clinical investigator sites

(Sharecast News) - Life sciences company Avacta has opened its first two clinical investigator sites in the US for a Phase 1 clinical study on its AVA6000 candidate.

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