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SOG showing my age but I remember watching West Ham win the World Cup with Moore Hurst and Peters lol.
Thanks for your informative posts and all's well with you.
Apologies to others for off topic!
GLA
I used to go to Upton Park regularly when younger and away games. back in the days of Trevor Brooking, Billy Bonds, Pop Robson. Mervyn Day and the likes. Not been for years but still keep an eye on. A few beers in the Boleyn as well.
Back to topic
Not long to wait however. for granting of CTA as sareum will receive preliminary decision this month.
Not sure if they will release info on this or wait until end of 60 days.
A little word here. Dont go looking up sar compounds. SAR20347 isa Sellick compound. Was confusing as is Tyk2 Jak1 Jak2 and Jak3 and the purity poor at 97%
A link below here of some compounds for those that may be interested in Kinase inhibitor make up of compounds.
https://www.selleckchem.com/products/sar-20347.html
Some great info and observations today on above today, thanks to all for sharing and C79 for bringing to the board ( a true 'ammer ;-) )
@ Thoth2 keep well and good to see your back musing!!
GLA
That is a patent for the compound itself I believe. Does not in anyway relate to the manufacturing of a compound as far as I can see.. Does correspond to autoimmune ie 1801
We have a patent grant circa Oct 21
https://www.lse.co.uk/rns/SAR/us-patent-granted-for-sdc-1802-tyk2jak1-inhibitor-9hk3sdpmxw35xkv.html
To answer your question it would appear that we have been granted patent protection regarding SDC1801
The patent (US 11,154,539) will grant on 26 October 2021 and will protect the SDC-1802 molecule and pharmaceutical preparations thereof as a therapeutic to treat cancer selected from pancreatic, colorectal and kidney cancers, melanoma, and B-cell lymphoma by inhibiting TYK2 kinase. This programme is in preclinical development.
It dose not relate specifically to crystallisation of a compound. Hence I would assume in the absence of any other factual reports we may not as yet be patent protected in this part of the invention in the USA.
From RNs Jan7th 2021
"The granting of this patent in the US completes the protection of the intellectual property for our proprietary SDC-1802 Programme across all major markets. The Board believes that the patent will enhance the value of its TYK2/JAK1 inhibitor programmes and the Company's negotiating position as it continues to engage in discussions with potential licence partners."
https://www.lse.co.uk/rns/SAR/us-patent-grant-for-tyk2jak1-anticancer-candidate-a8j5mz5b2ls6bxr.html
Certain we are patented up to the eyeballs.
Since both SDC1801 and 1802 are similar and crystallisation of a compound has been patented for 1802 I an contemplating as to why no mention of this or any indication that 1801 protected in same way.
It may well be from which group ie 0, 1 or 2 or combination thereof that 1801 is formulated by. There exists differing degrees of selectivity in these compounds.
Not entirely sure on this one.
This one hasn't been granted, has it?
https://uspto.report/patent/app/20210087154
Yes, thank you for the reminder SOG. The heat is addling....
Krone, good afternoon.
Patent for crystallisation of a compound was granted April 2022.
RNS
https://www.lse.co.uk/rns/SAR/european-patent-granted-for-sareum8217s-sdc-1802-jus0tdjz7hd5wzb.html
C79, thanks for the info. Looking at the co-inventors (Julian Northern) it would appear very likely that Onyx scientific are the people manufacturing the capsules for the trials.
"Our Phase I-III small molecule API development and manufacturing services support you through each preclinical research stage. Led by a team of highly skilled chemists, our approach focuses on seamlessly moving APIs from the lab to the plant, offering a smooth and flexible process from quality assurance and GMP manufacture through to analytical method development and stability testing".
https://onyxipca.com/cmc-services/?_gl=1*1yu6wsg*_up*MQ..&gclid=EAIaIQobChMI-aeBr8K--QIVwoFQBh2qOgWEEAAYASAAEgLJF_D_BwE#section-3
C79 - good find as usual. Is this the grant of the patent in which case we can expect an RNS?
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2021204762&_gid=202141
direct .pdf https://patentscope.wipo.int/search/docs2/iasr/WO2021204762/pdf/QQZRFpdWmwe0_qKNk8cFDVPZigreMjaEuGQC7h2IEUJ3k5JnbetNKynFh2qdm7r2zwQjcQ2bVFdY_ZVddEEt830V_Pk2EN1I-PRiwPGhMZLwoD9UKbEEqlC_GmhYC5eE
additional link:
https://register.epo.org/ipfwretrieve?apn=EP.2021058864.W&lng=en
ATB