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Valirx eyes partnerships as first VAL201 study hits the mark
. after its lead drug VAL201 showed evidence of efficacy in advanced prostate cancer in its first clinical trValirx’ recently-appointed chief executive Dr. Suzy Dilly pointed out that the data has been “generated using the utmost caution in sequentially dosing patients” and that future studies will try to “confirm these early indications of a positive response rate.”
great great article
sp will bounce back substantially
OR those big buys were the shorters closing their position.
Looking at the charts on Friday it was clear that from a technical perspective it was overbought and heavy and a retrace was needed. The only thing that would have countered a retrace was a stonking rns with someone that we didn’t already know. Ie, a deal.
That didnt come. So the retrace happened.
Bank
If they can drop it 50% in a day the other way can also happen.
The start maybe furious let’s see.
Eyeguy, 25% up sounds excessive, but a 40p (ish) sounds about right to me as I think this has been oversold and there was news of substance yesterday, so this could be a big bounce today.
I did notice the big value buys and sells. Not too fussed by the sales as they were quickly absorbed by the buyers.
More important is fact that there were big value buys which means that the big boys haven't sold out and are running for cover, rather they are taking advantage of the dip.
If they buys had all been tiny I would have been worried (smaller timers calling it wrong and compounding the error) but this isn't the case. Gla
Endometriosis market $2 billion per year
VAL 301 being trialled by global pharma.
Now safety profile of 201 has been met, can be applied to 301 too. Makes chance of something happening soon much greater imo
Bankfool- some big money came in sub 30p hence it dropped to get those orders in. Should be a +25% day today imo. 42p close imo
I found this article this morning
https://pharmaphorum.com/news/valirx-eyes-partnerships-as-first-val201-study-hits-the-mark/
Most others have posted it, but it is good to see that the results have attracted some media attention.
Looking forward to a better day today. Gla
From what I understand, there were reaction issues to the patients at the area of injection.
Asked the good lady to have a look at RNS - she’s lead oncology pharmacist at her hospital so respect her feedback above the vast majority on this board.
Didn’t sell any of my 112k shares today, btw! DYOR!!
Grace83, 18:16; "I don’t understand why the maximum tolerated dose wasn’t reached in the trial, as I assumed the adverse event would have been at 16mg/kg...which should have been why we knew they only went to 8. "
Grace, I have it in mind that at the higher doses the volume required to be injected became problematic. As I remember it, all doses were by injection. Sorry I can't provide a reference for this.
Grace, just found your message! It was buried!
Nice to read a calm(ish) post. I did enjoy the final remarks.
Plenty of frustrated people today, hopefully tomorrow things will a bit quieter after everyone has had the chance to sleep on it.
Onwards and upwards!
Grace
You have cheered me up with your last line, I think this will bounce back :)
Go and have a gin :)
Ok, while I’m still trying to make sense of all that’s happened today, I wanted to post so that people don’t think I have cut and run. I haven’t. Looking at the results, they are good. I can’t pretend that I wasn’t a little disappointed this morning, as I was hoping for very good or excellent, with some partial reductions thrown in. I agree with mathsprof about the trial design, in that it couldn’t show off the full potential of this drug. It doesn’t mean the drug is bad though. 54% success rate is a good rate in oncology trials. I don’t understand why the maximum tolerated dose wasn’t reached in the trial, as I assumed the adverse event would have been at 16mg/kg...which should have been why we knew they only went to 8. This will only become apparent in the full results, I guess. I would hope for some guidance from Suzy as to which direction we go in from here, as there’s more going on here than this RNS suggests. Also there’s more to 201 than this suggests too. Why would we need to redo the phase 1? I’ve been trying to interpret the wording of the RNS as the 8mg/kg dose worked. I genuinely thought this morning that the sp would go up, but not the two and threefold increases some were predicting...I didn’t expect it to go down and to the extent it did.
But anyway, I’m still mulling this over and feeling a little bit delicate about what’s happened today, but am definitely still in, as this has legs, in my opinion. Oh, and the people that are not in this share, or that never post but have come here to gloat today...it’s easy to pick holes in things when you are in possession of the results...anybody can do that. It’s not constructive and you can respectfully go and do one.
guess he made his money and ran
The news was good and this was played and tomorrow is another day in the AIM casino. After 9 years here, I was hoping the rise would have lasted a bit longer for me to reduce more losses a bit more or maybe breakeven, just have to wait a bit longer. Where is ST now, he appears to have gone silent? GLA