YGEN.L Regulatory News (YGEN)

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached: ii

Premaitha Health plc

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

ü

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to thenotification obligation: iii

Life Technologies Limited, a company incorporated in Scotland with company number SC083107

4. Full name of shareholder(s)  (if different from 3.):iv

5. Date of the transaction and date onwhich the threshold is crossed orreached: v

22 September 2016

6. Date on which issuer notified:

23 September 2016

7. Threshold(s) that is/are crossed orreached: vi, vii

Below 9% and through 9%, 10%, 11%, 12% and 13%

8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights x

Direct

Direct xi

Indirect xii

Direct

Indirect

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate xiii

Exercise/Conversion Period xiv

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction

Type of financialinstrument

Exercise price

Expiration date xvii

Exercise/Conversion period xviii

Number of voting rights instrument refers to

% of voting rights xix, xx

Warrants

24.6p

11 December 2023

Exercisable up to 11 December 2023

20,325,204

Nominal

Delta

8.9% (based on current share capital) and 7.07% (based on so-enlarged share capital)

Warrants

11.7p

11 December 2023

Exercisable up to 11 December 2023

17,094,018

Nominal

7.5% (based on current share capital) and 5.95% (based on so-enlarged share capital)

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

37,419,222

16.4% (based on current share capital) and 13.03% (based on so-enlarged share capital).

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable: xxi

Life Technologies Limited is a controlled undertaking of Thermo Fisher Scientific Inc. a company incorporated in the United States of America.

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will ceaseto hold:

12. Date on which proxy holder will cease to holdvoting rights:

13. Additional information:

14. Contact name:

Ted Fong

15. Contact telephone number:

001 (650) 244-1616