4 May 2016 07:00
VERONA PHARMA PLC - Verona to present RPL554 at the ATS ConferenceVERONA PHARMA PLC - Verona to present RPL554 at the ATS Conference
PR Newswire
London, May 3
Verona Pharma plc
("Verona Pharma" or the "Company")
Verona to present clinical data on RPL554 at the ATS International Conference
04 May 2016, Cardiff – Verona Pharma plc (AIM: VRP.L), the drug development company focused on first-in-class medicines to treat respiratory diseases, today announces that it will present three abstracts at the American Thoracic Society (ATS) 2016 International Conference in San Francisco, USA between 13-18 May. The abstracts will cover clinical data related to the Company’s lead drug RPL554, a novel inhaled PDE3/PDE4 inhibitor with both bronchodilator and anti-inflammatory properties, currently in development as a nebulised treatment for acute exacerbations in chronic obstructive pulmonary disease (COPD) patients in a hospital or home-care setting.
All three posters support Verona Pharma’s view that RPL554 could become an important, novel and complementary inhaled medicine for the treatment of respiratory diseases such as COPD, asthma, and cystic fibrosis.
All abstracts and details on timings can be accessed through the ATS website: http://conference.thoracic.org/
The title, timing and location of the poster presentations are as follows:
| Abstract | ID 13130 |
| Authors: | L. Bjermer, J. Stewart, K. Abbott-Banner, K. Newman |
| Title: | RPL554, a First-In-Class Dual Phosphodiesterase (PDE)3/4 Inhibitor, Is Equi-Effective as a Bronchodilator to Maximal Doses of Salbutamol in Asthmatics but with Fewer Adverse Events |
| Day/Date: | SUNDAY, MAY 15, 2016 |
| Location: | Area A (Hall D) Moscone Centre (North Building) P36 |
| Time: | 9:00 AM-4:15 PM |
| Session: | A31 - ASTHMA THERAPY: GLUCOCORTICOIDS AND BEYOND |
| Session Type: | Thematic Poster Session |
| Abstract | ID 6811 |
| Authors: | D. Singh, K.H. Abbott-Banner, F. Reid, K. Newman |
| Title: | A Phase I, Randomised, Double Blind, Placebo Controlled, Study To Assess The Safety, Tolerability And Pharmacokinetics Of Multiple Inhaled Doses Of RPL554 Administered By Nebuliser To Healthy Male Subjects And Stable COPD Patients |
| Day/Date: | WEDNESDAY, MAY 18, 2016 |
| Location: | Area A (Hall D) Moscone Centre (North Building) P71 |
| Time: | 9:00 AM-3:30 PM |
| Session: | D37-COPD: DEVELOPMENTAL THERAPEUTICS |
| Session Type: | Thematic Poster Session |
| Abstract | ID 4841 |
| Authors: | D. Singh, K.H. Abbott-Banner, F. Reid, K. Newman |
| Title: | A Phase I, Randomised, Double Blind, Placebo Controlled, Study To Assess The Safety, Tolerability And Pharmacokinetics Of Single Inhaled Doses Of The Dual Phosphodiesterase 3/4 (PDE3/4) Inhibitor RPL554 Administered By Nebuliser To Healthy Male subjects |
| Day/Date: | WEDNESDAY, MAY 18, 2016 |
| Location: | Area A (Hall D) Moscone Centre (North Building) P72 |
| Time: | 9:00 AM-3:30 PM |
| Session: | D37-COPD: DEVELOPMENTAL THERAPEUTICS |
| Session Type: | Thematic Poster Session |
-ENDS-
About Verona Pharma
Verona Pharma's lead drug, RPL554, is a first-in-class drug currently in Phase 2 trials as a nebulised treatment for acute exacerbations of COPD in the hospital setting. The drug is a dual phosphodiesterase (PDE) 3/4 inhibitor and therefore has both bronchodilator and anti-inflammatory effects, which are essential to the improvement of patients with COPD and asthma.
Verona Pharma is also building a broader portfolio of RPL554-containing products to maximise its benefit to patients and its value. This includes the very significant markets for COPD and asthma maintenance therapy. In addition, the Company is exploring the potential of the drug in different diseases, such as cystic fibrosis, where it is in pre-clinical testing and has received a Venture and Innovation Award from the UK Cystic Fibrosis Trust.
About ATS International Conference
The ATS International Conference is the home of pulmonary, critical care, and sleep professionals, from those in the earliest stages of their careers to people with research or strides in clinical care, which has gained them international recognition. Each year, nearly 14,000 of these professionals choose to attend, present, and learn about the latest advances, meet with colleagues from around the world, and strike new collaborations. It is truly where today’s science meets tomorrow’s care.
The International Conference is also multidisciplinary. Clinicians and researchers in many other fields attend the conference, thereby enriching conversations that lead to insights that ultimately improve patient care. Among the many other specialties represented in sessions at the International Conference are:
Allergy/Immunology, Behavioural Science, Cardiology, Environmental and Occupational Health, Infectious Disease, Paediatric, Pulmonary, Critical Care and Sleep
Equally important, the ATS International Conference gathers the entire health care team in one place to share ideas across these medical and scientific disciplines. It is the ideal place for nurses, respiratory therapists, and hospitalists to discuss their experiences, challenges, and research so that all can learn about the latest advances in understanding pulmonary disease, critical illness, and sleep disorders. And of course, the International Conference is truly international: 40 percent of attendees arrive from laboratories and patient care centres beyond the United States.
Further information on the conference can be accessed via the following weblink: http://conference.thoracic.org/
For further information, please contact:
| Verona Pharma plc | Tel: +44 (0) 20 7863 3300 |
| Jan-Anders Karlsson, CEO | |
| N+1 Singer | Tel: +44 (0)20 7496 3000 |
| Aubrey Powell / Jen Boorer | |
| FTI Consulting | Tel: +44 (0)20 3727 1000 |
| Simon Conway / Stephanie Cuthbert/ Natalie Garland-Collins |