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Director Dealing

16 Feb 2026 07:00

4basebio Plc - Director Dealing

4basebio Plc - Director Dealing

PR Newswire

LONDON, United Kingdom, February 16

16 February 2026

4basebio PLC

("4basebio" or the "Company")

Director Dealing

Cambridge, UK, 16 February 2026  – 4basebio PLC (AIM: 4BB), an innovation driven biotechnology company enabling and accelerating development of advanced therapy medicinal products (ATMPs) through its high performant GMP-grade synthetic DNA products, announces that on 13 February 2026 it was informed that Dr. Amy Walker, Chief Executive Officer of the Company made the following purchase in ordinary shares in the capital of the Company through the market.

Further details are set out in the Notification of Dealing Form below.

Director / PCA Number of Ordinary Shares Acquired Purchase Price (Aggregated) (p) Shareholding Following Acquisition Shareholding Following Acquisition as a Percentage of Issued Share Capital
Dr. Amy Walker 2,650 586.08 46,666 0.30%

The 2,650 shares purchased represent approximately 0.02 per cent. of the Company's issued share capital.

The issued share capital of the Company comprises 15,538,518 ordinary shares.

This announcement contains inside information for the purposes of Article 7 of EU Regulation 596/2014 as amended by regulation 11 of the Market Abuse (Amendment) (EU Exit) Regulations 2019/310.

For further enquiries, please contact:

4basebio PLC +44 (0)12 2396 7943
Dr Amy Walker, CEO
Cairn Financial Advisers LLP (Nominated Adviser ) +44 (0)20 7213 0880
Jo Turner / Sandy Jamieson / Ed Downes
Cavendish Capital Markets Limited (Joint Broker) +44 (0)20 7220 0500
Geoff Nash / Nigel Birks
RBC Capital Markets (Joint Broker) +44 (0)20 7653 4000

Kathryn Deegan / Matthew Coakes

ICR Healthcare (Media and Investor Relations)

Mary-Jane Elliott / Jessica Hodgson

+44 (0)203 707 5700

Notes to Editors

About 4basebio

4basebio (AIM: 4BB) is an innovation driven life biotechnology company focused on accelerating the development of advanced therapy medicinal products (ATMPs) through its high-performance synthetic DNA products and non-viral, cell targeting nucleic acid delivery platform. The Company’s objective is to become a market leader in the manufacture and supply of high-quality synthetic DNA products for research, therapeutic and pharmacological use as well as development of target specific non-viral vectors for the efficient delivery of payloads in patients.

Forward-looking statements

This announcement may contain certain statements about the future outlook for 4basebio. Although the directors believe their expectations are based on reasonable assumptions, any statements about future outlook may be influenced by factors that could cause actual outcomes and results to be materially different.

Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them

1 Details of the persons discharging managerial responsibilities / person closely associated
a) Name Dr. Amy Walker
2 Reason for the notification
a) Position/Status Chief Executive Officer
b) Initial notification/ Amendment Initial notification
3 Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a) Name 4basebio plc
b) LEI 213800E2DX9EAIUNCB30
4 Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a) Description of the financial instrument, type of instrument Identification code Ordinary Shares ISIN: GB00BMCLYF79
b) Nature of the transaction Acquisition of ordinary shares
c) Price(s) and volume(s)
Price(s) Volume(s)
586.08p 2,650
d) Aggregated information - Aggregated volume - Aggregated Price 2,650 586.08p
e) Date of transaction 13 February 2026
f) Place of transaction London Stock Exchange


Date   Source Headline
22nd May 20269:10 amPRNDirector Dealing
20th May 20267:02 amPRNFinal Results and Notice of AGM
20th May 20267:00 amPRN4basebio Signs Clinical Supply Agreement to Support Phase II Clinical Trial
14th May 20267:00 amPRNAppointment of Chief Financial Officer and Board Changes
11th May 20267:00 amPRN4basebio Launches Enzymatic ssDNA Platform
31st Mar 20267:00 amPRNLease of Manufacturing Facility
12th Mar 20267:00 amPRNAppointment of COO
3rd Mar 20267:00 amPRNAppointment of CCO
16th Feb 20267:00 amPRNDirector Dealing
11th Feb 20263:58 pmPRNDirector Dealing
10th Feb 20267:00 amPRNLeadership Changes
27th Oct 20257:00 amPRNSynthetic opDNA® utilised in Phase I/II US clinical trials
10th Oct 202511:30 amPRNResult of Extraordinary General Meeting
30th Sep 20254:20 pmPRNDirector Dealing
29th Sep 20257:00 amPRNHalf-year Report
22nd Jul 20257:00 amPRNEmployee Long Term Incentive Plan and Issue of Equity
8th Jul 202510:30 amPRNDirector Appointment, Board Change
3rd Jul 20257:00 amPRNHolding(s) in Company
3rd Jul 20257:00 amPRNHolding(s) in Company
2nd Jul 20257:00 amPRNHolding(s) in Company
2nd Jul 20257:00 amPRNHolding(s) in Company
27th Jun 20256:05 pmPRNResult of AGM
25th Jun 20257:00 amPRNExercise of Options
17th Jun 20257:00 amPRNHolding(s) in Company
17th Jun 20257:00 amPRNHolding(s) in Company
27th May 20257:00 amPRNFinal Results and Notice of AGM
4th Apr 202512:00 pmPRNDirector Dealing
2nd Apr 20257:00 amPRN4basebio Receives GMP Licence for its UK DNA Manufacturing Facility
25th Mar 202510:15 amPRNHolding(s) in Company
14th Mar 20257:00 amPRNRBC Capital Markets initiates research coverage
7th Mar 20257:00 amPRNEmployee Long Term Incentive Plan and Issue of Equity
3rd Mar 20254:37 pmPRNDirector's Dealing
8th Jan 20257:00 amPRNAppointment of Chief Commercial Officer
17th Dec 20247:00 amPRNDirectorate Change
29th Nov 202412:30 pmPRNDirector's Dealing
19th Nov 20242:15 pmPRNDirector's Dealing
15th Nov 20245:31 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20245:30 pmPRNHolding(s) in Company
15th Nov 20247:00 amPRNHolding(s) in Company
14th Nov 20247:00 amPRNAppointment of Joint Corporate Broker
12th Nov 20247:00 amPRNCompletion of Strategic Investment

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