Member Info for xviolet

i meant to say 3.3 paid!

3.3p
now off to work.
good luck all.

blueandwhite said...

"The market makers have scared you into doing exactly what they wanted."

Great post blueandwhite. If this is orchestrated then it seems to have 2 intentions: 1. make us sell. 2. persuade us not to buy. So we get out of the way so someone else can move in? Good luck all.

PH has been blamed. Alternately the appt of PH could have prompted someone else to make their move. And brought them out of the shadows. If there is a pattern in the buys and sells - and even in the postings here - to suggest an attack of some kind. (I've been watching Sandbaggers again - maybe 2nd best ever TV spy series).

They're all very miserable on the SAR bb. Amazing how much it has gone down. I'm suddenly very glad I never invest very much. I can't imagine it is the choicest investment on the block at the moment. But I've liked all the medical papers I've read about their science and inhibitors etc...I might even buy a bit more if it keeps sinking...still each to their own!

nice post potnak.

in the face of the unknown - and for me there's a lot of unknown here...sheer stubbornness does fine.
and getting on with other stuff in life and just not looking at the market for a few weeks. or longer.

oh sorry the post didn't disappear. I just couldn't find it. shouldn't be doing the day job and looking at this at the same time. so turning off now. but will buy a few in my lunch break.

Did Num4's post just disappear? The one where it was alleged this sp action was an attempt to make room for an incoming investor/fund-rase - the disappearance of the post....does that tell us anything...I think the missing post alleged this sp action is an attempt to make room for an incoming investor/fund-raise. I guess buy the odd dip and wait for the RNS/TR-1.

proving difficult to get rid off?
I think some posters on Friday were reporting no problem selling. And there was a one million buy on Friday (one million shares, that is).

I think Mafuta's posts have been very helpful. The drop is so close to the PH news that its hard to believe there isn't a connection. Perhaps there isn't but for the short-term - or until some facts emerge, I am assuming the drop is orchestrated. I bought some last week and I am happy to hold them for several years, but I appreciate that many long term holders will see things differently. Everyone has their own budget, their own time-line and their own strategy.

Thanks for that. I bought SAR hoping to be able to take some profits and bury the rest in the pf for the future - however it may have a lot further to fall. I think thats likely but I still bought at 4.25ish because of fomo!

I think 737 to Sierra was their one license deal to date. Sierra have done some trials (including succesful in-human trials) but nothing much seems to be happening atm. But maybe it will all take years and years.

Re: DC-1801 (autoimmune diseases and severe Covid-19)
first clinical studies scheduled for mid '22.

so yes. maybe a long wait.

yeah yeah its a side play. yeah its a long long way off. but maybe the heat is being turned up on treatments. and I know merck and pfizer will get there first....but still....its a long, long game. see ya in 2022!

https://www.nbcnews.com/politics/white-house/unvaccinated-biden-bets-billions-covid-treatments-another-surge-threatens-n1284093

biden buying pills.
synairgen's turn may well come in such a climate.

https://www.nbcnews.com/politics/white-house/unvaccinated-biden-bets-billions-covid-treatments-another-surge-threatens-n1284093

Bought a load this AM. Sub 4.5p seemed like a good price. No idea if this is going to sink to the lower depths or if the current drop is highly suspect, coming so soon after Peel Hunt's appt as their broker. I have been reading about their science...there are some safety issues, some great promises...and I need to read more. This article was good, I thought, for background. And suggests one of Sareum's molecules may have a better safety profile than one of Pfizers (recently semi-mothballed).

https://lifescivc.com/2021/03/selective-allosteric-tyk2-inhibitors/

"Sareum is advancing internal programmes focused on distinct dual tyrosine kinase 2 (TYK2) / Janus kinase 1 (JAK1) inhibitors through preclinical development as therapies for autoimmune diseases, including the 'cytokine storm' immune system overreaction to Covid-19 and other viral infections, (SDC-1801) and cancer immunotherapy (SDC-1802)."

thats the side play. stuck in there. looking good. for a side play.
makes me feel optimistic.

Thank you. That was very articulate and elegant writing. You should do a book!

BOJO2020

Great. I'd be very interested to hear your opinion. I've just started reading about TYK1/JAK inhibitors and Sareum - by the time I understand the science I'll probably be dead and buried. But we soldier on. :)

Either on miserable downwards trend or sp tweaked downwards by Peel Hunt (their new broker) prior to fund-raise or ii incoming (thats a guess btw). But seems cheap compared to recent highs.

So yeah...SAR may have always have had the edge.

" Pfizer calls its PF-06826647 compound a ‘TYK2 inhibitor,’ but as we look at the data, it is not selective, as it clearly hits other JAKs along with TYK2"

https://lifescivc.com/2021/03/selective-allosteric-tyk2-inhibitors/