--DSM Patent Published8 Mar 2022 17:35
https://patents.google.com/patent/EP3917555A1/en?q=fruitflow&assignee=dsm&sort=new&clustered=true
DSM Bay Leave & Pollution patent published in December 2021 - FF mentioned
Abstract
The present invention relates to systemic detoxification and chronic inflammation by using extract fractions of Laurus nobilis, that lead to a decrease of anti-inflammatory markers in human lung cell lines and the activation of the Nrf2 pathway, which is a crucial element in intracellular detoxification pathways, decreases the expression of inflammatory cytokines. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.
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Fractions of a Laurus nobilis extract, enriched extract, or at least one compound selected from the group of Formula 1, 2, and 3, or and mixtures of at least two of these compounds of this invention may be combined with other active ingredients to make a composition which has beneficial results. Examples of further active ingredients include Vitamin E, water soluble tomato extract, resveratrol, Vitamin D, 25-hydroxy vitamin D3, hydroxytyrosol,
polyunsaturated fatty acids (PUFAs), Vitamin A and mixtures thereof. Thus, this invention also includes the following combination of ingredients:
Fractions of a Laurus nobilis extract, enriched extract, or at least one compound selected from the group of Formula 1, 2, and 3, or mixtures of at least two of these compounds and Vitamin E;
Fractions of a Laurus nobilis extract, enriched extract, or at least one compound selected from the group of Formula 1, 2, and 3, or mixtures of at least two of these compounds and water-soluble tomato extract (such as FRUITFLOW® available from DSM Nutritional Products, Switzerland);
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