Charles Jillings, CEO of Utilico, energized by strong economic momentum across Latin America. Watch the video here.
http://www.patientwing.com/study/386687?layout=default&studySiteId=3232995&showAdvancedDetails=true
More info, and the recruiting status only shows up on the copy and paste
Available locations
The Beatson West of Scotland Cancer Centre NHS Greater Glasgow Clyde
Not yet recruiting Glasgow, GBR G12 0YN
St James's University Hospital The Leeds Teaching Hospitals NHS Trust
Not yet recruiting Leeds, GBR LS9 7TF
The Christie NHS Foundation Trust
Not yet recruiting Manchester, GBR M20 4BX
The Freeman Hospital Newcastle upon Tyne NHS Foundation Trust
Not yet recruiting Newcastle upon Tyne, GBR NE7 7DN
Weston Park Cancer Centre Sheffield Teaching Hospitals NHS Foundation Trust
Not yet recruiting Sheffield, GBR S10 2SJ
Cracking find Losta. Goldiloc13 this is the 1st paragraph on the Royal Marsden page:
This open-label, First-into-Human (FIH) study will evaluate the safety, tolerability, pharmacokinetics (PK) and early efficacy of AVA6000, a FAP-activated pro-drug of doxorubicin, in patients with locally advanced and/or metastatic solid tumours. In Phase Ia, using a 3+3 design, escalating doses of AVA6000 will be administered to patients with a range of solid tumour types to determine the maximum tolerated dose (MTD) and/or recommended Phase II dose (RP2D). In Phase 1b, the selected RP2D dose will be assessed in one to three tumour types.
I read an article re PARP inhibitors a little while back but, altho they appear to be effective, they are deemed too expensive to be used long term, which is what the treatment requires. At £4000 per month that is £50,000pa so I don’t believe we need to be concerned that they might be a competitor to our own Pre|cision. I’ve posted a link to NICE.org so I hope this helps
https://www.nice.org.uk/guidance/ta381/documents/final-appraisal-determination-document
Pdub, I've just seen the news and I'm gutted for you. We've 'known' each other on this BB for over 5 years, with all its ups and downs, and together we've fought off many a troll (well, it was you mostly, but I did help a bit!) and we revelled in the ride up to 149p (altho unfortunately the next bit wasn't quite so enjoyable).
Anyway, I just want to say how shocked I am and to sincerely wish you and your family and GND the very best for the future. Stay strong mate!
@longrun, the news was that 50k patient swab samples were sent to the US for lab testing as we don't have enough lab capacity in the UK to run them all here. The results will be sent back to us for 'validaton'. And bigbench is right, the Govt, the NHS and the country do need our tests right now.
From RNS 6/4/20
General Meeting to be held at 10:00 a.m. on 23 April 2020.
Admission will become effective and trading in the New Ordinary Shares will commence on or around 8.00 a.m. on 24 April 2020.
https://finance.yahoo.com/news/bushveld-minerals-limited-lon-bmn-084501140.html?.tsrc=rss
Today we are going to look at Bushveld Minerals Limited (LON:BMN) to see whether it might be an attractive investment prospect. In particular, we'll consider its Return On Capital Employed (ROCE), as that can give us insight into how profitably the company is able to employ capital in its business.
First of all, we'll work out how to calculate ROCE. Next, we'll compare it to others in its industry. Then we'll determine how its current liabilities are affecting its ROCE.
What is Return On Capital Employed (ROCE)?
ROCE is a metric for evaluating how much pre-tax income (in percentage terms) a company earns on the capital invested in its business. In general, businesses with a higher ROCE are usually better quality. Ultimately, it is a useful but imperfect metric. Author Edwin Whiting says to be careful when comparing the ROCE of different businesses, since 'No two businesses are exactly alike.
How Do You Calculate Return On Capital Employed?
Analysts use this formula to calculate return on capital employed:
Return on Capital Employed = Earnings Before Interest and Tax (EBIT) ÷ (Total Assets - Current Liabilities)
Or for Bushveld Minerals:
0.41 = US$90m ÷ (US$245m - US$25m) (Based on the trailing twelve months to June 2019.)
Therefore, Bushveld Minerals has an ROCE of 41%.
Check out our latest analysis for Bushveld Minerals
Is Bushveld Minerals's ROCE Good?
When making comparisons between similar businesses, investors may find ROCE useful. Bushveld Minerals's ROCE appears to be substantially greater than the 13% average in the Metals and Mining industry. We would consider this a positive, as it suggests it is using capital more effectively than other similar companies. Putting aside its position relative to its industry for now, in absolute terms, Bushveld Minerals's ROCE is currently very good.
Current liabilities include invoices, such as supplier payments, short-term debt, or a tax bill, that need to be paid within 12 months. The ROCE equation subtracts current liabilities from capital employed, so a company with a lot of current liabilities appears to have less capital employed, and a higher ROCE than otherwise. To counteract this, we check if a company has high current liabilities, relative to its total assets.
Bushveld Minerals has current liabilities of US$25m and total assets of US$245m. Therefore its current liabilities are equivalent to approximately 10% of its total assets. The fairly low level of current liabilities won't have much impact on the already great ROCE.
http://www.miningweekly.com/article/mantashe-says-ministerial-determinations-needed-to-unlock-irp-2019-are-finalised-and-await-nersas-concurrence-2020-02-19/rep_id:3650
"Mantashe also announced an easing of limitations on licensing of generation for own use of above 1 MW, which he said would mainly be used to supplement power supply to commercial and industrial customers including the mines.
"Installed capacity above 1MW is unlimited. Since May 2019, Nersa has received 18 applications, totalling one 116 MW, in this category. Most of them are incomplete because they lack power purchase agreements, which is a requirement to show who the consumer of the power is and to indicate connection agreements for consumers still dependent on the national grid."
for those that were complete, Nersa would move the licence the plants within the prescribed licensing timeline of 120 days."
to allow the IPPs to ride to the rescue of Eskom and SA:
http://m.engineeringnews.co.za/article/wind-and-solar-bodies-urge-minister-to-publish-determinations-needed-to-kick-start-power-procurement-2020-01-28/rep_id:4433
https://www.fin24.com/Budget/moodys-changes-sa-outlook-to-negative-but-its-not-junk-yet-20191101
Another reprieve for SA