Gordon Stein, CFO of CleanTech Lithium, explains why CTL acquired the 23 Laguna Verde licenses. Watch the video here.
denby .. I would like to think I am 100% wrong, but I really do not see it. If GSK get the un modified version of mRNA right on a combination vaccine with Covid -then medium term it possible to gain some revenue... There is now 35 vaccine approved, 9 in India made at its seat factorys with no quality control - as Astra found out
To many vaccines have just been waved through at will, those made in India by E Biological the Baylor Texas vaccine from P Hotez is another example of India being used as a experiment ground.. Clinical trial of 2500 people again shows how the regulatory process as been thrown in the air and bad vaccine enter the market.
The UK messing about with Toxic Paxlovid antivirals is beyond belief
Growing body of evidence validates Vir’s approach of targeting a highly conserved region of the spike protein –
– Together with recent pseudo- and live virus results, additional preclinical data reinforce sotrovimab retains in vitro neutralizing activity against all known variants of concern, including the highly divergent Omicron variant –
https://finance.yahoo.com/news/vir-biotechnology-announces-research-describing-134700486.html
Can not see GSK having any decent returns on vaccines now, the UK EU USA all signed up to Pfizer/ Moderna till 2023.
Other nations have better options for vaccines than the EU UK, USA- GSK Sanofi only chance that as is if Gavi use it.
GSK will make decent returns for the Monoclonal Antibody and a mRNA flu vaccine .
If Canada approves Medicago it will help-but that is low numbers of vaccinations
Sotorvimab.
While the UK shirks its responsibilities on providing the life saving treatments people need, the USA as used up this month’s stock of 100,000 doses. In my opinion its not expensive, it save on an ICU bed at $25,000 per day
It sent out 55,000 doses on December 17 and another 49,552 doses on December 27.
The USA will take delivery of a a further 325,000 doses on January 3 rd.
In my opinion its not expensive, it save on an ICU bed at $25,000 per day
Sotrovimab as no completion, it is the only treatment for Omicron and Delta Plus.
Evushiled failed against Omicron coming in at 32% and against Delta at 41% and Delta plus at 37%.
Regeneron had a Efficacy against Omicron of 38% , but fared better at 51% on Delta.
Eli Lilly bamlanivimab/ etesevimab
On Antivirals, we have serious issues, and how the UK as even placed orders or plans to use it is beyond Comprehenesion.
It trial was as bad as it vaccine trials, it was trialed in 2164 people, none hospitalizsed , none with underling health conditions.
Its actual FDA EUA was never voted on by the CDC or FDA, it was waived through by Rochelle walinksly the CDC Director .
What is 100% factually known on Laxlovid is it causes Hepatotoxicity is extraordinary high. i. It can not be used with warfarin, contraceptives, steroids,s tatins. 85 Cases of hepatitis, and jaundice have occurred in patients receiving it in the trial with ritonavir.
It key failure is not discussed in deatail.
Paxlovid as to be given within 48 hours of a positive covid test, that in the USA is a strategic Nightmare as they have no testing like the EU.
Worse is this simple fact, it is a 5 course treatment of tablets that cost $17.00 to make, and they are sold worldwide at $590.00.
It cannot be given twice, if a person as a reoccurrence of Covid in day 7 or day 30, they cannot have anymore.
A GP cannot prescribe if you read Pfizer actual filing to the FDA, it states a person must have a complete medical evaluation of the Vascular system, including the heart echocardiocram and Pulmonary Lung Fuction tests, both of those are in hospital settings s, they must also have a full Liver scan before taking it and complete blood word,
It offers no protection at all, like Mercks Monupalivir and Monupalivir is a Carcinogenic pill like Paxlovid .
Sotrovimab is unique, as it not only neutralizes Omicron and all variants, it offers full protection of 85% still after 10 months, it is better than any vaccine and dose not cause Myocarditisis like Pfizer or Moderna, it dose not cause Vaccine Thrombocytopenia like Astra Vaccine.
I am lost at the antics of Sajid Javed, he is 100% not fit for any purpose in the health sectors.
Unfortunately over 50,000 UK citizens have died that never needed to if the MRHRA and Health sectary rolled out Sotrovimab like Australia and UAE, JAPAN did in June and July.
Evushiled as no effect on Omicron, its less than 10% on Delta plus. GSK VIR have the only 3 monoclonal antibodys that work and proven in peer reviews
https://www.nature.com/articles/d41586-021-03825-4
People pushing Astra fail at the basics
Only 3 Monoclonal antibodys work on Omicrom, no Antiviral dose, so Pfizer and Merck are pushed out just because the vaccines fail.
Todate, Astra Fails miserably on Delta Plus and Omicron-same as Regeneron-Gilead -Lilliy
the UK is failing to order the 3 million doses it needs and has less than 50,000 .
GSK VIR have the only answer
https://www.nature.com/articles/d41586-021-03825-4
TO LATE, they used poor vaccines, then poor mAbs, even in the USA they used on on anyone who asked for it.
Astonishing how GSK is a UK company-and as the treatment that everyone should be given, like 20 other countrys use it.
Sajid Javed is in Pfizer pockets still from his days at Chase Manhattan
Dunnie, it will need at least 10 million doses to survive through till February just on vulnerable.
USA CDC is collapsing - Pfizer Vaccine FAILED.Pfizer Pill FAILED, next up a mAb that as already been shown in a trial of 300 people to not even neutralize Alpha, Beta, Delta
AS no effect on Omicron after 2 months- get ready you will all need a 1 a month dose of this crap, as that is all the UK is using
https://www.medrxiv.org/content/10.1101/2021.12.20.21267966v2
dunnie, as long as Pfizer can make $30 billion from a pill , the thick British will buy it.
https://twitter.com/Doctor_I_am_The/status/1473990089034412034
denby.
That I would have a issue with in may aspects.
The UK as brought 500,000 Regeneron Monoclonal antibody, that cost is $2,600 per dose and as no effect on Delta plus (AY.1 -AY.2) It as no effect on Omicron (B.1.1.529). Florida actually ceased use of Regeneron on Monday-like most other states.
Astra Zeneca EVUSHELD (AZD7442) had a Efficacy of 51% on Delta Plus AY.1 AY.2 and 32% on Omicron (B.1.1.529)
Giving Pfizer antiviral pill which as no substantive data on Delta-Delta Plus and is diminished completely on omicron without showing above 0.65% on pre clinical data- means the UK are throwing away $670 - for a course of tablets that are taken over 5 days . Pfizer clinical trial data is actually on 2164 people, take away the placebo and its 1082 in one trial
Sotrovimab from GSK underwent 5 clinical trails in 5 countries . On one trial it was halted early due to its results, that led to the United Arab Emeriates taking delivery andusing in 6000 people in a trial of there own..Data in link below https://www.mediaoffice.abudhabi/en/health/uae-announces-2-week-treatment-results-for-covid19-medicine-sotrovimab/
The UK as failed at the very basic level and when you thought it could get no worse under Hand**** - it did with Sajid Javed who buys anything with the stars and stripes flag on it, even Donald Trump Mugs
riskingit
UAE 50,000 May
Singapore 50,000 June
Australia 30,000 July
Brazil 20,000 July
Canada 15,000 July
Italy 10,000 July
EU 220,000 , they procured them in June
USA 300,000 , they obtained them in September
UK 100,000 they put order in December , as they brought the Pfizer vaccine failure and ordered Pfizer pills..Odd, UK Company that worked on Sotrovimab for 22 months so far and the UK Conservatives , only buy US vaccines and monoclonal antibody that fail.
Must be difficult to imagine how a UK Company has the answers and UK people do not get it, while other countrys do.
Glaxo Share is approx 30% a
Fidepax1
Pfizer Antiviral pill as no comparison at all. First that pill can only be given once in 3 months. Its a 5 day course and only treats symptoms, it as no prevention or protection at all.
Sotrovimab gives protection and treats the illness, it loses no efficacy at all. Its EV is still marinated at 80% after 10 months, no vaccine can match this.. It naturalizes every variant, not one variant as stood up again Sotrovimab.
Pfizer anti V Pill costs $670 and it does not work on Omicron and as a EV of 54% on Delta+
Merck pill..Today France rejected it after requesting more data and it was 30% effective on the original variant and less than 10% on others. France canceled its orders of Mercks pill..
Cost of a ICU bed in the UK NHS is over £25,000 per day
The mAbs primary purpose is to treat people who can not have vaccines, that means over 1 million in the UK.
The UK only brought 100,000,.
Pfizer and Merck Antiviral fail against delta and Omicron. You can only have 1 course of the antiviral pill at a cost of $640 per course that is 5 days. Once the course is finished, you can contract it again 3 days later and you can not have the Antiviral pill again for 4 months- you can only have a maximum of 3 courses full stop.
Once give the GSK VIR mAbs as no escape, its efficacy as not been effected at all after 10 months.
Astra mAb failed against Omicron, it only 51% efficacy in testing, it was only 63% against Delta an dlost its efficacy after 2 months .
GSK VIR mAb will possibly come in a GSK Vaccine
Dunnie.
I do not understand the phrase should work. https://twitter.com/ScottGottliebMD/status/1471996258051137541
All data as proven its effective against every Variant -even Omicron.
No patient as to be Vulnerable in EU or USA to receive it..Looks like living in France is better-as you do not need an underlying illness.
You do not have to test positive-its Efficacy as not dropped in 9 months .
It can be given to anyone, the UK NHS may restrict its use, but it will be the treatment of choice.
Antiviral drugs only last for the period taken- if you contract covid after taking a course of antiviral drugs from Merk or Pfizer, you need a further course - and the limit is one course every year..
GSK Monoclonal Antibody- shows it retained it's Efficacy after 9 months against every variant and not dropped by even 0.5% .
Vir GSK are making it now as an alternative to Vaccines - where people catch Covid 19 after having 3 vaccinations
Glaxo magic
https://www.washingtonpost.com/health/2021/12/16/monoclonal-antibody-sotrovimab/
What proactive fail to disclose
Key sentences
AstraZeneca announced Thursday that its long-acting monoclonal antibody, which was recently authorized as a treatment to prevent illness, was likely to retain protection against omicron. It is a ****tail, "and a preprint study had suggested that omicron could escape the individual components of the ****tail"
https://www.washingtonpost.com/health/2021/12/16/monoclonal-antibody-sotrovimab/