AVACTA's LFT23 Sep 2020 13:54
uses the same affimers as in the Avacta ELISA test:
Using the same Affimer reagents that are incorporated into its rapid coronavirus saliva test being developed with Cytiva, Avacta has developed in-house a high performance ELISA laboratory test to detect the SARS-CoV-2 virus. Avacta will make the ELISA test available as a kit so that researchers globally can use it in their own laboratories to support research into the coronavirus.
which is 500 times more sensitive than the competition:
https://avacta.com/alastair-smith-gives-more-detail-on-the-sars-cov-2-elisa-laboratory-test/
IT WORKS!!! the issue is manufacturing capacity:
Avacta, in partnership with Cytiva, is developing a rapid test strip for use with patient saliva that aims to provide a result in a few minutes, indicating whether the patient is currently infected with the SARS-CoV-2 coronavirus. The test has the potential to be used for frequent mass testing of the population to promptly identify infectious individuals so that they can be isolated and treated, thereby reducing the spread of infection.
Abingdon Health provides innovative rapid testing solutions to a global client base and has Europe's largest lateral flow test contract manufacturing capacity. Abingdon Health's two sites in York and Doncaster, UK are able to produce millions of rapid tests per month.
Authorities around the world are now looking to carry-out frequent mass testing to identify the most infectious people promptly in order to reduce infection rates and combat the coronavirus pandemic. That requires a highly specific test to minimize false positives which would otherwise overwhelm healthcare systems. The Affimer reagents that we have generated are very specific to SARS-CoV-2 antigen and we are confident of meeting and exceeding the clinical performance requirements for identifying the most infectious people.
Manufacturing capacity is therefore the key challenge that has to be met in achieving widespread roll-out of Avacta's saliva-based rapid antigen test. We therefore continue to actively seek additional manufacturing partners globally to be able to provide the volume of tests that will be required in the UK and elsewhere. I look forward to updating the market on progress in that regard, and will keep the market informed on the key next steps of clinical validation and regulatory approval.
I for one am very very confident that Avacta will pull this off. Currently its out of their hands for clinical validation and manufacturing.