RE: Excellent safety profile10 Dec 2023 08:21
Phase 1a is only focussed on safety and tolerability and finding an MTD.
They haven't found an MTD (but have proved therapeutic levels of dox released), which speaks volumes.
As an extra bonus efficacy has also been observed, with a significant reduction in an STS patients tumour (who had run out of options and was end of life).
The data should be pretty good ....