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Is it not plausible that synairgen will have a ballpark figure regarding success in that say they have delivered 10 courses of treatment to a certain hospital to treat 10 patients .Subsequent follow up calls ( without unblinding and perfectly acceptable ??)to the hospital reveals that say of the 10 treated . So many improved substantially to no limitations ,so many improved slowly but did get better,so many advanced to more serious disease which required additional treatment ,sadly so many died .etc,etc ,
Then by statistical evaluation using what we know from P2 regarding efficacy ( 79 %, 3-1 marked improvement ,time to no limitations etc) and adjusting for "placebo effect " .Then contacting all hospitals concerned worldwide, would that not give them a Conservative evaluation as to how the trial has progressed ? Or does "Double blinding " include that Synairgen have absolutely no idea how many patients are selected in each hospital around the world and distribution of drug is totally third party ? Can anyone clarify please ?
I have already accepted a one for one share offer with Astra zeneka
Somebody at Az will be in serious trouble me thinks if some other pharma buys it after giving away their options on the drug when it was being primed for Asthma. They may well outbid everyone with a huge offer to save face .SNG001 will be infamous as the super drug Astra Zeneka gave away having paid for a great deal of its development .They may just have a "Brando " moment and indeed make us an offer we can't refuse .
That must be pretty hilarious for you ...........and poly ofcourse .
Really Ndn71 ????? How immature.
I bought in because Interferon sounds like messing with ladies bits .
Then why not buy in obscure/ odd numbers if they are so desperate to fly under the wire and remain incognito until legally forced to show their hand ?
I shall probably watch Jerry Lewis in the nutty professor instead .Rather watch an actor playing the incompetent quack than the real thing tbh .
Yep!!!!!
If there's going to be lots of people in a small pub we'd better inbox Richard to bring a shed load of SNG001.Me thinks it will be needed the way things are going. lol
Thought it was one of the jedwood twins at first sight but then noticed it was jwd. Still, it could be as they are both a couple of thick as fcuk daftys aswell.
Actic 2 P3 is scheduled for closure in Dec 22, not Sprinter ( early 22)
I think Homer Castro had a "DOH" moment and tried an 'off the cuff / get out of jail 'response by making the second statement regarding safety .I'd imagine all safety protocols were established and approved before efficacy was examined.
100,k treatments was a target set by synairgen long long before the Americans enroled us onto warp speed / activ 2 .
I couldnt give a cluck what he says tbh.
Is synairhen the generic formulation made with chicken ovaries? If so then I'm inclined to agree with you
Ofcourse there will be incurred costs to Synairgen for activ 2 .Drug and inhaler supply and all the safety and quality protocol administration and then repeated upon " seamless advancement to P3". I should imagine we have permanent company representation over in the States to make sure things run smoothly. Dont think it will run in to millions but there will be costs .Anyhow it shouldn't be ten million and wasn't it stated that the monthly cash burn was £2.5 million but that was before the extra recruitment but that is just salary .
Didn't Synairgen effectively save £10 million when the P3 trial was reduced from 910 patients to 610 ? And that it was acknowledged at the time that it cost in the region of £33000 a patient to test .That is where the £10 million saving came from ( 300 x £33000) .Ofcourse activ 2 will have incurred unforseen costs but that £10 mil was still a handsome bonus.
Speaking of SP, The MMs seem to be having a little botty burp and raising the price a tad .
IMHO it's the monthly MM games to stimulate trading but I sincerely would like to be way off mark .
IMHO vaccine passport is a con . Just back from spain to my house in Holland . I am double jabbed( free) and incurred no extra costs whatsoever either going or coming back( No test reqd. ) Uk travellers needed to trace, book and pay for an antigen test before going home and to have pre booked a pcr test for day 2 when home . Total rip off for UK travellers and even if you disagree with european policy , All tests are free and instantly available here in the Netherlands ..