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Phase II Biomarker Data for SNG001 to be presented
Fri, 27th Sep 2019 07:00
RNS Number : 8778N
Synairgen plc
27 September 2019
RNS REACH
Press release
Synairgen plc
('Synairgen' or the 'Company')
Synairgen to Present Phase II Biomarker Data for SNG001 at the European Respiratory Society International Congress
Southampton, UK - 27 September 2019: Synairgen (LSE: SNG), the respiratory drug discovery and development company, is presenting biomarker data from the first part of its ongoing Phase II trial of its wholly-owned antiviral therapy inhaled interferon beta (IFN-beta) in patients suffering from chronic obstructive pulmonary disease (COPD), at the European Respiratory Society (ERS) International Congress being held in Madrid 28 September - 2 October 2019.
Exacerbations of COPD are associated with disease progression and are a major cause of the healthcare burden associated with this common disease. A significant proportion of exacerbations are caused by respiratory viruses, such as those that cause the common cold and flu, when infections spread to the lungs.
Synairgen's two-part Phase II trial, called SG015, has been designed to assess Synairgen's inhaled IFN-beta in COPD patients when they have a cold or flu infection. The data being presented are from Part 1 of the study, in which patients were treated with inhaled IFN-beta when they did not have a cold or flu infection. Analysis of samples from the lung shows that treatment with IFN-beta boosted the lungs' antiviral defences, increasing Synairgen's confidence in the likelihood of a positive outcome in Part 2 of the study in which inhaled IFN-beta is being assessed when patients do have a confirmed respiratory virus infection.
The data will be presented by Synairgen's Chief Scientific Officer, Dr Phillip Monk, at the Congress on Sunday 29 September in the session entitled "COPD clinical trials: new molecules and novel insights" (8.30 to 10.30 am Room 6F).
Professor Tom Wilkinson, leading international lung disease specialist and Chief Investigator for the SG015 study, commented: "Respiratory