Wtf cat out of the bag24 Mar 2020 21:03
To date, early data from this double-blind, placebo-controlled trial have demonstrated that the antiviral responses in the lung (assessed using sputum biomarkers) are similar to those observed in the asthma trial, where we saw clinical benefit in lung function.
Dr Richard Marsden, CEO of Synairgen told Thailand Medical News, "We have worked intensively with the relevant authorities and collaborators to enable SNG001 to be assessed in Covid-19 patients. SNG001 has been well tolerated in clinical trials in over 200 respiratory patients to date and has accelerated lung function recovery in two Phase II asthma trials in patients with a cold or flu infection. A successful outcome from this trial in Covid-19 patients would be a major breakthrough in the fight against this coronavirus pandemic."
Dr Stephen Holgate, Medical Research Council (MRC) Professor of Immunopharmacology, said, "The reduced innate immune response that exists in the lung of those at most risk of serious Covid-19 disease such as older people and those with pre-existing lung disease makes such patients ideal candidates to receive inhaled SNG001 to replace their interferon deficiency. This is especially so because SARS-CoV-2, along with MERS-CoV and SARS-CoV, is equipped to evade this first line of viral defence. In the absence of a suitable vaccine, increasing the host's own immunity to enhance protection and virus elimination would seem a logical therapeutic approach."
Dr Tom Wilkinson, Professor of Respiratory Medicine at the University of Southampton and Trial Chief Investigator, further added, "We are facing an unprecedented health challenge with Covid-19 which desperately requires the rapid development of new therapeutic strategies. There are a limited number of candidate new treatments available and so it is vital we can rapidly generate high quality evidence on the role of these in Covid-19 patients. The UK research delivery and regulatory teams have worked incredibly effectively to enable this world leading trial to achieve approvals so rapidly which has enabled our motivated and highly expert team of researchers to get this vital study running straight away."
For more details, please view: https://www.synairgen.com/ (please do not overwhelm them with calls or product enquiries. The drug is in experimental stages and not meant for sale to individuals or even medical entities or companies, only government to government deals involving trials will be entertained at this stage.)
For constant updates on Covid-19 Drug Research updates, please keep on logging on to Thailand Medical News
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