Member Info for SYN00GOLD

Shorters working very aggressively.

Major situation developing in the USA. March/April current forecasts predicted to explode., and lets face it, the USA are a mess now !!!!!

https://www.bbc.co.uk/news/world-us-canada-55684878

Meanwhile recovery trial (Horby & Landray) has completely crashed and burned for the randomized trial of convalescent plasma >10,000 patients shows no benefit. Should have gone to Specsavers and held with SNG001 !! The other 2 variants are also starting to give the USA headaches.

https://www.wsj.com/articles/u-k-covid-19-variant-likely-to-become-dominant-u-s-strain-in-march-cdc-says-11610733600

SNG are going to need to massively up production when the Activ-2 trial shows patients showing signs of recovery. Brace yourselves :-)

Agree re-gift horse !
Just think about what Dr Marsden has stated a few times, that as of early 2021, plan is to upscale and manufacture 100, 000 treatments per month via Akron et al, and these will be priced at £2000/treatment. I believe he has already committed to agreements with which guarantees production slots etc etc. Therefore if initial manufacture is now already rolling out in the factories at this level, and as he was using 30 million approx. for this purpose - I am guessing that between now and end of June, Synairgen will have at the very minimum 600, 000 treatments on the shelf (however we do know that last year he was getting some manufactured, without knowing volumes).
This means that without any other outlay, we will have sales of £1.2 billion immediately done IF all goes well in P3. This in itself values an mcap at the very bare minimum of £6 per share without any forecast multiples as per norm.
Whatever happens, we can be certain that huge scale up is already being set up and who knows 'what else' in the background...…..multiple JVs ????
On these very simple calculations alone, we should brace ourselves for a massive uplift in SP, However, success rate @P3 stage for respiratory is considerably higher than most disease area i.e. oncology/CNS/CV

https://blogs.sciencemag.org/pipeline/archives/2019/05/09/the-latest-on-drug-failure-and-approval-rates

My research calculates the chance of success now is minimum 75% for natural biological.
https://www.acsh.org/news/2020/06/11/clinical-trial-success-rates-phase-and-therapeutic-area-14845

My view of success is approx. 90% from here based on current science Phase 2 result, ACE2 short form Nature publication
https://www.nature.com/articles/s41588-020-00759-x
and all the other stars aligning, ACTIV-2, FDA Fast Track status, home trial (which is now in all probability known), dire straits of infection/mutations...…
I believe Professor Sir SH knows that the results of the home trial are already validating what has been observed in P2 trials and that is why he is staking his reputation on outlets such as SKY tv etc. The man is not a fool.

This is going to explode IMHO quite soon. AND I think most LTH's secretly know it.

...............and I thought you starred in the wedding singer - that wasn't you pmjh ?

Major situation developing in the USA. March/April current forecasts predicted to explode., and lets face it, the USA are a mess now !!!!!

Meanwhile recovery trial (Horby & Landray) has completely crashed and burned for the randomized trial of convalescent plasma >10,000 patients shows no benefit. Should have gone to Specsavers and held with SNG001 !! The other 2 variants are also starting to give the USA headaches.

https://www.wsj.com/articles/u-k-covid-19-variant-likely-to-become-dominant-u-s-strain-in-march-cdc-says-11610733600

That would by luvvly jubbly..................this time next year Rodders !!!!!

Will do -)

Just out of boredom, COB today-£1.70p

RNS's gonna come thick and fast next week, prepare for rockets !!!!

Biden will spend 2 Trillion $$$$ to ty and combat virus and boosting economy. He can have SNG001 for a mere $5 billion if he acts fast :-)

Don't Woody :-)
My sphincter muscles still twitch from 9 or 10th November when we went from 1.79 to £1 in 30 minutes !!!!!
Even then however, I kept saying to myself, science is solid !!!!

Oxford - I wasn't using the normal EPS or price multiples applied to commercial stock prices, so a massively good base !!!

Oh Scinv, I took you out of the bin 2 days ago, but I feel let down, time for your re-entry bud.

If stupid could fly, you'd be a jet. I would try and insult you BUT, am afraid I won't do as well as nature did !!!!!

Hi All,
Just think about RM has stated a few times now that as of start of 2021 plan is to upscale and manufacture 100, 000 treatments per month via Akron et al, and these will be priced at £2000/treatment. I believe he has already committed to agreements with which guarantees production slots etc etc. Therefore if initial manufacture is now already rolling out in the factories at this level, and as he was using 30 million approx. for this purpose - I am guessing that between now and end of June, Synairgen will have at the very minimum 600, 000 treatments on the shelf (however we do know that last year he was getting some manufactured, without knowing volumes).
This means that without any other outlay, we will have sales of £1.2 billion immediately done IF all goes well in P3. This in itself values an mcap at ultimate ultimate bare minimum of £6 per share without any forecast multiples as per norm.
Whatever happens, we can be certain that huge scale up is already being set up and who knows 'what else' in the background...…..multiple JVs ????
On these very simple calculations alone, we should brace ourselves for a hugh uplift in SP, However, success rate @P3 stage for respiratory is considerably higher than most disease area i.e. oncology/CNS/CVhttps://blogs.sciencemag.org/pipeline/archives/2019/05/09/the-latest-on-drug-failure-and-approval-rates

My research calculates the chance of success now is minimum 75% for natural biological.
https://www.acsh.org/news/2020/06/11/clinical-trial-success-rates-phase-and-therapeutic-area-14845

My view of success is approx. 90% from here based on current science Phase 2 result, ACE2 short form Nature publication
https://www.nature.com/articles/s41588-020-00759-x
and all the other stars aligning, ACTIV-2, FDA Fast Track status, I will stop now as getting too excited and starting to lose my focus on scientific objectivity :-)

WARNING This is a ramp :-) Just because I'm feeling the need.....plagiarism thanks to 'abrooking' !!! :-)

May even do again on RNS for Activ-2 start

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I cannot replay enough times :-) Love it !!!! Its like see fireworks exploding in the night sky. Pure Gold

Well said Chris. I think the yanks are way ahead IMHO already. UK Gov are just watching from the sidelines and trying to milk any glory.

Hi BG - Just saw this.....

https://twitter.com/Synairgenplc/status/1349324534286065664

They are all coming out of the woodwork !

Just want to say massive thank-you for your detailed investigative work/analysis on behalf of all shareholders. I know that there are a number of others too (you all know who I mean) that have worked their *******s off to support analysis of SNG001 current status.
Most importantly, the news that I have seen on video with my own eyes and ears discussing adding nebulized IB1a to the trial in the USA, I truly believe will blow our pants off. Not maybe initially, BUT, once the message is grasped and comprehended, will take our drug into new dimensions re-commercial sales in USA. This is were the big $$$$$$ will be realised.
So thanks again pmjh, CW, bitethebull, Dafad, Trinity,Oak, Org, Doc, Ghia, Bella, Mr B (grumpy recently :-) TrekM, Vola, Matml, Zwart, TornadoT, Hold4R, PhilG, Tav, CityT, Spinnaker, WoodS1970, Nessab, Tim, MattW007, Nolupus, JoeyD et al) toooo many to ramble on !!!!

This is gonna be a once in a lifetime share. DO NOT SELL YOURSELVES SHORT :-)

As Buzz Marsden would say 'to infinity and beyond'.

Thanks for the updates TT - you have been brilliant on this forum. The range you quotes will be way north of this by end of Feb :-)

Keep up the great work.