The latest Investing Matters Podcast episode featuring Jeremy Skillington, CEO of Poolbeg Pharma has just been released. Listen here.
Worth watching this video from 12 mins
'BA.2 is taking over and does not have the same s-gene PCR target failure as BA.1.'
This new mutation of Omicron will have the same implications for Affidx LFT, therefore being able to detect it again? Quick upgrade to cover both variants and we're back in the race.
Things could get quite interesting!
https://youtu.be/n09uw2wzF1o
Elrics article is free for everyone btw.
Think its clear todays rise was a combo of being at the bottom of the chart with things turning very nicely, along with Oxford covid19 recruitment for the challenge studies. Effectively gives the green light for us?
https://smallcompanychampion.substack.com/p/open-orphan-plc-35a?r=kcv2o&utm_campaign=post&utm_medium=web
Looks like no Cathal, bit surprised but maybe for the best for now!
Agree. She did well last time putting him under some heat.
Might even see an appearance from your favourite person too!
They posted this last week:
Our #CEO & #Chairman will be presenting at the
@proactive_UK
#virtual #One2One #Event next Thursday 20 January 2022 at 6:30pm. We look forward to updating #investors on our Company #updates & what to look forward to in 2022.
"London will be back to normal this year and prices per sq meter will shoot up again."
Have you been to that part of London? If not, go! Its like a ghost town. I pass through there regularly.
Anyway I don't see space as an issue anyway, theres always SGS we can hit up if we need to. Otherwise I fully expect a merger/takeover to happen later this year after approvals have been given and then start spending money. Which given recent published documents by Gov etc, it seems very close now, simply a waiting game. To write human challenge studies into pretty much their future plans and guidance is a massive endorsement for Orph/Hvivo.
Pointless spending cash when theres no immediate need to.
I would also start reading where the Gov are allocating money to, IMO there is funding available to help with the pandemic preparedness which includes the 100 day vaccine plan (human challenge studies a key part of this), theres a plan in place and just trust the process.
Brilliant interview Elrico. Many thanks for doing it and sharing.
Bright future ahead, and personally feel that hes doing a great job given how young the company is and the speed things are progressing at.
Looks like testing will be here for quite some time! Clear the boat hasnt quite sailed yet, particularly with even more scrutiny on the tests against Omicron, and that they wont buy Chinese. We still have an open goal, just the net got a bit smaller with the delay with the antibody issue!
WASHINGTON (Reuters) -U.S. President Joe Biden is directing the U.S. government to procure an additional 500 million COVID-19 tests to help meet surging demand across the country amid the spread of the Omicron variant, a White House official told Reuters on Thursday.
The order comes on top of another 500 million tests that the White House pledged would be available to Americans in January.
"In addition to the 500 million tests that we are in the process of acquiring, today he is directing his team to procure 500 million more tests – to meet future demand," the official said, speaking on condition of anonymity.
Biden has come under criticism https://www.reuters.com/article/us-health-coronavirus-biden-analysis-idCAKBN2IZ0WD for not focusing more on testing earlier as part of his strategy for fighting the pandemic. A nationwide shortage of tests has plagued the response in recent weeks during the rampant spread of the highly contagious Omicron variant.
Biden plans to announce his order for the additional procurement later on Thursday.
The official said the tests would be free for American consumers and that the White House would share more details about their distribution at a later date. Details about the website that will have information on the first tranche of 500 million tests will be available on Friday, the official said.
"How is the oncology side of business going to be funded without a raise? And a big one."
Well if ava6k PK data is good and IF there are no side effects, that opens up a $150billion per annum industry. It opens the door to many new partnerships with royalty payments and milestone payments, that can fund it in itself.
But let's humour you and say a placing does happen, it would be on the back of the data readout which would be a premium fundraise at many times the current share price, so yes it will be a big one, a big share price by that time. Would do some research into premium fundraises and why they happen, and it's not to keep the lights on!
For me the investment pictures has changed but it's more of a binary play now than before. However the upside on good data is mind-blowing and the signs are currently very good, FDA IND, no bad effects notified to us so far etc.
On the paper itself
"In real-world antigen testing, the limit of detection was substantially lower than manufacturers have reported to the FDA based on laboratory validation
we defined infectious viral load as corresponding to Ct value <29 in this analysis."
Will be very interesting what Affidx/Meduflow gets on Omicron given <29 is very similar area to where we got our best data at 100/100 <28 I believe?
@Zoom0001, ever thought that it might be wise not to sell our capacity to the first bidder?
Theres global demand and pressure for tests, articles are coming out saying some are paying 25% extra just to secure supply compared to prices last week. Theres bidding wars out there, but in order for us to be in the driver seat with negotiations, we need a stockpile of tests and the future capacity to go with it.
Biden promised 500m tests and his administration said last week that deals would be finalised at the end of next week (so this week). Say we have been stockpiling for 1.5m now, we could have nearly 50m tests ready to ship straight away if going on the assumption of 1m tests a day and that they give us EUA (have looked into the requirements, and see no obstacle at all for this). Along with Medusa saying USA coming soon the dots start to connect.
I would want them to hold back and let each country that wants our supply enter a bidding war so we get the best margin.
Fantastic find Spbhoy.
I was on the website a few hours ago and it said "sold out" as the test wasn't available yet.
Very interesting that it now says it's possible to add it to the cart and
Pickup available at The Annex, Glasshouse
Usually ready in 2 hours
Things are definitely moving along!
Appreciate it and Merry Christmas to you.
One last one before Xmas! Is it us? Could we have a small slice of the pie? I certainly believe so giving what was found yesterday regarding EUA for covid tests which can be approved in a matter of hours or days. Now we have EU HUA, this is the real catalyst to going even further. The US wouldn't want all our capacity going to EU when they can approve us.. would they?
1m capacity a day, charge over £10 for a test, few £ profit a test, utterly transforms the company
President Biden acknowledged his administration has struggled to meet demand for Covid-19 tests in an interview with ABC News Wednesday, telling David Muir, “Nothing’s been good enough.”
Biden said he expects the rapid tests his administration have ordered “will start going out in the beginning of January, because they're being produced now,” and confirmed that he, and members of his family, would test before celebrating Christmas together in person this weekend.
Looks like we might be hearing something about the USA very soon! EUA?
https://mobile.twitter.com/Joe_Hond/status/1474124044077314055
And currently there is very high demand for the goods
https://mobile.twitter.com/Turkstocks/status/1474117815594536961
The AffiDX® SARS-CoV-2 antigen lateral flow self-test will be marketed by Medusa under the brand name "MeduFlow".
Here we go.
Capacity and orders next up, APAC approval, capacity and external capacity next up too. Dose escalation due along with ava3996. Merry Christmas all!
Timster, all the main guys, Myles, Littlegunner, Poirot have all vouched for me that it's real and even confirmed from the company it was pre marketing material. Unbelievable that you still maintain its a Photoshop. You won't be able to find a single post of mine thats fake, and those in the telegram group will vouch for me too. Believe what you wish, but you'll soon find out how wrong you are, and I doubt you'll even apologize for throwing such accusations around either.
Very likely it was a worked buy given the price action today. Would have been nearly impossible to offload anywhere near that amount so high.
Also BN who knows his stuff said the following:
"im being to be that guy that says for every seller there has to be a buyer on the otherside. Given the price action i would say its a buy, MM had to buy up the market to get the fill, the VWAP (Volume weighted Average Price) prior to the deal going up was 3.8 mio ave 22.24p"
Possible short closing out? Looking at Jupiter. They had 0.84% on their last reported update. So thats around 2m shares, this was just shy of that.
RSP was looking solid all day really, so if it wasnt a short, this would be worked over a few days.
The 73k trade was the daily spreadbet btw Mustang, always the 17:06/07 trades.
Just processed at 114p, time being 17:13.
Massive trade!
This from the Sunday Times: The chancellor has been warned that previous assumptions about the coronavirus may have to be torn up after the emergence of the highly transmissible Omicron variant, which appears to be more resistant to vaccines.
The latest crisis has led the Treasury to draw up plans to fund a booster programme in which adults will be given a jab every three to six months, possibly indefinitely, if dangerous mutations continue to appear.
Information shared with the Treasury suggests that Covid is going to be a “much more dominant feature of our lives than we had thought”, which has triggered a reappraisal of its spending.
“The scientists all said, ‘Vaccines are going to mean you are home and dry, so spend billions on vaccines’, which is what we have done,” a Treasury source said. “But if that has changed and this is basically life, the view is that every three to six months another one of these comes along and we are all going backwards.”
The source added: “If the assumptions have all changed, which it looks like they have, you quite quickly get to £4 billion or £5 billion per year, and that is just on vaccinations and boosters.”
100% of IG client accounts with open positions in this market expect the price to rise
0% of IG client accounts with open positions in this market expect the price to fall
251 – 500 IG client accounts have open positions in this market
https://www.ig.com/uk/marketanalysis/ig-shares/avacta-group-plc-AVCT-UK