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“This led to 18x more dox in the tumor than the standard dox.”
I suspect IIs, the market, big pharma are currently waiting for this headline, and the underlying data. Hopefully interim numbers and data will be released on/after the science day, but, as a secondary outcome, we may have to wait until the study has been completed/findings published.
If efficacy can match that seen in mice; 18x more dox with lower levels of cardiotoxicity, it would be monumental.
This might be p1/p1b study but dox’s mechanism of action is well understood. Essentially, AVA6000 is a platform for delivering more dox with less risk of side effects so efficacy would mostly be answered at p1/p1b, p2 would probably just scale up and look at typical dox/cancer outcomes. When the trial reports in summer/autumn, IIs and big pharma should get all they need.
Yet another ‘mistake’ in a litany of mistakes. Farcical at best.
Argo has to go down as one of the worst managed publicly listed companies in history. Mistake after mistake, poor decision after poor decision, false statement after false statement.
I’m glad I sold my position around 40p, at a significant loss. I feel sorry for all those that were hoodwinked by PW, and may have lost life-changing sums of money.
“To reduce further cascading negative effects of FTX, Binance is forming an industry recovery fund, to help projects who are otherwise strong, but in a liquidity crisis. More details to come soon. In the meantime, please contact Binance Labs if you think you qualify.”
“…otherwise strong, but in a liquidity crisis.”
“…otherwise strong…”
That rules Argo out.
FTX was a top 5 exchange by daily volume; there will be implications for other coins/tokens/currencies.
I can see a significant fallout; some smaller exchanges will topple, other coins/tokens/currencies will be come worthless, lots of unmet obligations, lots of liquidity crunches.
I suppose we’ll start to find out within the next week or so, but I think the crypto sector still has some distance to drop yet.
Hopefully, people will start to shun sh*tcoins and altcoins, and look to Bitcoin as the only crypto worth investing in.
Also, I hope the huge amounts of leverage are flushed from the system and that it remains low - whilst leverage led to BTC’s massive growth in value during 2021, it also led to the following rug-pull.
Regulation of the exchanges is pretty much nailed on after this; which I think will be a positive outcome for Bitcoin.
Tether is getting hammered. If it drops much further and is viewed to have lost its dollar peg, it’ll likely collapse.
Collapse of USDT would be huge - it could be the death knell for crypto. To all invested in the crypto sector, keep an eye on USDT.
I’m not convinced $14k is the bottom - everybody is talking about it as some golden entry point.
Every man and his dog will pile in on leverage at $14k, just perpetuating the problem of the sector being massively over leveraged. Subsequently, whales will just continue to do what they’ve been doing for the past 2 years by taking the price in the opposite direction to where the average retail investor thinks it's going to go in order to accumulate more bitcoin.
The sector is in a mess.
I noticed he retweeted a theory about how this meltdown came about:
https://mobile.twitter.com/LucasNuzzi/status/1590122590206824448
Interesting. If true, the ramifications could be huge. It points to potential fraud, and obscene greed and ruthlessness.
I think heavy regulation is much more likely after this.
I know the whole ‘Bitcoin is dead’ joke, but I get a sense of foreboding - SBF and CZ could well have mortally wounded the entire crypto sector today.
Do we have any indication when the DFS has been pushed back to?
Are we likely to be looking at closer to 3 months or 6 months later than the initially planned Dec 22 date? Or could it be longer? I’d imagine that waiting too long wouldn’t be in NCM’s best interests due to Telfer running out of ore.
I’m looking forward to Argo Blockchain the movie.
- Benny Hill theme tune
- Life of Brian meets All The President’s Men meets Mr Bean The Movie
- Rowan Atkinson reprising a Mr Bean-type role as Peter Wall and Alex Appleton
- Christian Bale reprising a Big Short Michael Burry-type role, as Chaebol, but with less stress/margin calls
- Courtroom drama element yet to be scripted
You do know there’s a strategic investor doing their DD on a 20% stake in Argo right?
Thought I’d let you know as you hadn’t posted on this board before the previous 2 days’ pump and I’m sure you know very little about the company.
I think Alex brought Argo to its knees - as he’s responsible for the company’s finances. PW certainly failed in his strategic decision making, but I suspect many of his decisions were heavily influenced by finances/Alex. Additionally, the NASDAQ listing debacle falls squarely at his feet.
I think Seb, responsible for strategy and investment decisions, also offered very little. BTC obviously caught many people out, but no selling BTC, no hedging, and riskily funding growth through debt is amateurish at best.
I think that generally sums up Argo; a bunch of amateurs/bitcoin enthusiasts who found themselves running a sizeable bitcoin mining company and, through poor decisions, managed to bring it to its knees. I don’t think this assessment is exclusive to Argo either; I get a similar impression from several other major bitcoin miners.
The current situation stinks to high heaven. Last week’s RNS was a monumental ‘mistake’. It surpasses all the other awful strategic decisions taken over the past 18 months by some margin.
It’ll be interesting to see where ARB and the board end up after this debacle is over.
Surely the deal with the strategic investor has collapsed at this point. Current SP is -~50% of the agreed price!
The investor will be asking for more shares, which I don’t think is possible, as PW doesn’t have the authority to issue any more in addition to those agreed in the sale.
I can see ARB being bought on the cheap by one of the big publicly-listed miners.