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NY what matters is how much is hitting the tumour compared to a dose of normal dox. One way of increasing that is to give more frequent doses. Avacta will know the conversion rate because they are measuring pK of the leaving group. They have chosen not to communicate this to the people who own the company. I suspect potential new owners have seen it.
NY they haven't given 2x the dose of dox. They give ava6000 a % of which is converted to dox. The MOA is that concentrations are very high at site of conversion. See last set of Q and A which confirms it is notb100% conversion.
Probably worried about appearing to be boosting. Think they are going to need a bigger venue for next AGM.
Just seen bloke over on twitter collecting votes for no confidence motion
That's not a bad strategy but you would normally implement it before you spent a shed load of hard to come by cash on two overpriced Dx companies and then fail to leverage your own in-house IP
AS to board last week
Big science presentation at major event in April
Let's accelerate a book build before anyone sees this paradigm shift.
Whilst you are at it I've had ago at Dx for about 20 years and my last effort was truly awful. One day someone might get tested with an affimer they paid for. Until then would you mind reseting my options package.
Where is Mr 7 make it 8 questions when we need him?
Great made up word. Looks like it wasn't true.
Don't worry - again not true
Improve communications. I rest my case
EF do the honourable thing and just go. Hand back all your options and perks cause you haven't earned them. I really don't think we need to go through the whole appraisal, HR, performance appraisal thing do we.
Bump
Why would they buy shares when they award themselves massive option packages. They wouldn't risk their own money when they win massively if it comes off and lose nothing if it doesn't.
Who. How?
There are some large retail share holder groups. I'm happy to lend my vote to anyone who proposes that AS and EF leave Avacta.
Agree. I would also add Elliot F to the P45.
The pair of them have overseen award after award of share options that replace any where they failed to hit the target. This raise was well known before PIs were given the info and I suspect the same group of II were responsible for the sell off as soon as price was agreed in principle last week.
How do we get rid of them
Have cash ready - market can be slow to react whereas PIs can get in at start
Last I heard myles and the pom pom girls were all boasting about how they has a sneaky top up at £1.06.
Genuinely I hope it comes good for them (and me) but not sure why they think continually getting it wrong needs to be broadcasted all over social media. Perhaps tone down the certainty. Hopefully some new inputs for the magic calculator soon.
Suspect AS and EF have either seen sense or it was never going to happen. Little bit of history repeating.
If affyxell float are avacta in for swapping their % for cash ?
Avacta part own affyxell. Affyxell don't own the affimer IP. They have interest in very limited number of affimers.
Avacta could sell their share and raise money. Affyxell get on with proving concept. Avacta then sell more affimers but could lse out on both capital gain and revenue depending on deal for affyxell.
To me makes more sense than selling diagnostics if Dx strategy was sound.
100,000 buy sell incoming. Magic calculator is warming up
Can I check that someone will still daily post the 100,000 trade and ask is it a buy or a sell
So we have agreed our compromise statement.
We the people front of lse agree, in principle but not blindingly so, that, subject to verification, the Sp may (or may not) move to £1.87 but will be £1.37 before this point.
It's a magic number. Above this 46% of the lse board retire