Member Info for RegulatorUK

"The mere fact they are choosing to make an announcement to market on Monday and not Friday indicates news will be positive."

That's not what the RNS says. The suspension is until the announcement is made or until the opening of the Australian exchange on 10 May (which is Monday) - which ever is earlier. The opening of the ASX in Sydney is 9 hours *ahead* of London exchange. If news were be announced to the London Exchange on Monday morning at 7.00 a.m. they'd potentially miss the ASX business hours.

I'd expect news to be announced to the London Exchange tomorrow.

"But why allow LSE to continue?"

Different exchanges have different rules.

The RNS is clear that the halt is "pending the release of an announcement by the Company in relation to further findings on ArtemiCTM".

It means one of two things: either very positive news (e.g. approval by Health Canada or another regulator) or very poor news (e.g. rejection by Health Canada or poor test results).

Simple fact is, we won't know until the announcement is made. If people are going to sell, that may be a gamble they regret...

Binned it. Don't have the time to waste reading that sort of bo11ock5.

"The GP/Dentists Distributor news was positive."

Numed are tiny... Numed Healthcare was dormant as at April 2020 (according to Companies House).

They're up against established multi-million (and in some cases multi-billion) pound companies with established supply chains.

Green binned. Total ********.

I think we're getting some amuse bouche before the entree and main course...

1.05 and falling...

"This update was how it was over a month ago.
Those orders could drop any minute now!"

Eh? The 30 April 2021 was last Friday... not a month ago.

"The Company is pleased to announce that it has entered into a distribution agreement with Numed Holdings Limited (www.numed.co.uk), who will supply the P2F mask into GP, dental and veterinary surgeries, opticians and care homes across the UK and Ireland."

Numed Holdings is a minnow in a very large pond. It's main healthcare company was dormant for a number of years.

" I'm sure you'd feel happier if your GP or Dentist or your grandma's care worker had an anti-viral mask (Covid, Flu etc etc) on - rather than one produced to the cheapest possible price?"

They may be targeting those sectors - doesn't mean they'll make substantial sales into them. GPs and dentists will be subject to similar IPC requirements as hospital clinicians, which makes a 7 hour mask somewhat redundant. Whoever's currently managing the marketing (and I am somewhat hesitant to use the word) 'strategy' clearly doesn't have a clue about the sector.

Hopefully an experienced CEO - if they can get one - will give this floundering BoD some proper direction and focus their attention on the markets where this mask, and subsequent products, will have best penetration.

"RegUK and the fact it's by FIND gives it so much more credibility"

Absolutely! This is now the second (IIRC) independent validation of the Mologic test.

I note in his recent presentation, the Almighty Alistair indirectly floated the proposition that his test may not be part of the sovereign test programme. Not many Avactolytes appears to have spotted that...

"m invested in both shares Regulator, but have to correct you on that point. Avacta sample size was 200, not 100.
98 positive and 102 negative samples."

My bad - 3 1/2 times bigger. And if I recall correctly, this is the second independent validation of the Mologic test...

They're rudderless, with no CEO, and hopeless, with no real strategy.

I leave my holding as is for now, as it's money I can afford to lose, but I expect the price to drop sharply and any recovery will be a long time coming. Lets hope they can get someone in as CEO who is competent and capable - we need it.

Bunsenburner's been sniffing the gas a little too much...

"Good to see them playing the game. 665 sample size, nice. Best in class, lovely."

Nearly 7 times the sample size of a certain other test...

"Lol why would that be? Surely they would want the qudos BEFORE the elections as a vote winner?"

The pre-election protocols mean that they should not announce anything nationally that might influence voters locally. I understand that Whitehall are being quite strict this time round, due to the behaviour of the Tories in the 2019 elections.

"I will concede that to you Regulator. But there are the test readers and the tests themselves which are new devices that need to be developed"

Again, I think you misunderstand (or perhaps don't wish to understand) the process...

"They are not using ActiPix for the Covid test. As per the September RNS"

I think you misunderstand what the September RNS is talking about. I refer you to the RNS of 6 June 2020:

"Concept

The test involves the deployment of a DNA aptamer - a short, single-stranded DNA molecule that adopts a shape that is complementary to that of the virus surface protein. By coating a test surface with millions of copies of the aptamer molecule, Paraytec's CAPTURE module can trap Covid-19 virus particles from a swab sample, as they flow over the test surface. Trapped viruses are then instantaneously coated with the SIGNAL GENERATION module, a synthetic chimeric protein, that both recognises the viral surface as well as being highly fluorescent. The resultant fluorescent signal is measured by the DETECTION module using a version of Paraytec's patented Actipix area imaging technology configured for fluorescence detection.

Technical Summary

In order to avoid using live Coronavirus in the lab during proof of concept, an artificial version of the virus is used, the surface of which mimics the Covid-19 virus, by displaying the precise protein (SPIKE) on it that the virus uses to gain access to human cells. The CAPTURE module comprises a fluidics system in which a specialised surface is coated with the COVID-19 DNA aptamer. Virus particles are trapped on the surface by the DNA aptamer. In order to detect trapped virus, Paraytec's SIGNAL GENERATION module uses a synthetic bi-functional protein, that both recognises the virus as well as emitting light. This enables trapped viruses to be visualised by a version of Paraytec's ActiPix system that detects UV and visible light as well as fluorescence. The CAPTURE/SIGNAL GENERATION modules, in the presence of the virus SPIKE coat protein, generates a specific light signature, which may be detected by ActiPix.

...
WP3 Construction of SIGNAL GENERATION module

In order to detect trapped virus, a synthetic bi-functional protein is used, that both recognises the virus as well as emitting light. This enables trapped viruses to be visualised by a version of Paraytec's ActiPix system that detects UV and visible light as well as fluorescence.

...
WP5 Configuration of ActiPix for fluorescence signal DETECTION

Adapt the currently available ActiPix system with appropriate fluorescence excitation and emission filters. Build system with flow-through cuvette and test designs for a disposable cartridge.

..."

The simple fact the device (the ActiPix system) already exists and is being used in a number of scientific settings. These are not new devices - what has been developed is their ability to be used for diagnostic purposes in the context of Covid and other diseases. CE marking may therefore be a relatively short and straight-forward process.

However, I think Paraytec have been clear that this will be done in conjunction with a third party.

Is the six months roll out going to be an issue? No. What has been proven is that this technology can be used for diagnostic purposes - and that opens up a whole new series of markets.