the drift is down30 Mar 2017 10:33
I was looking back on the older RNS: 19th Sept: "......As previously reported, first-in-human studies for the Porcupine inhibitor, initially as a stand-alone therapy, are expected to commence early in 2017.......". In-human studies doesn't seem to have happened - I am sure that explains all as regards current price.
We hope it will come good in the end (as long as they don't run out of cash again!).