Member Info for panman

You're almost correct on the push back statement but it reads like you don't have all the facts. The last time prostrate testing was looked at it was decided no as they only had the PSA test and with its unreliability issues they didn't want Dr's promoting it unless and until their patients knew its limitations. Even the MRI has limits hence the follow up biopsies.

The consensus now is that PSA can be followed up by PSE (if not given at the same time?) so changing the reliability of the early stage testing hence the new look at testing and push for same.

Didn't disagree just updated and should also note from yesterdays push that these tests aren't presently for "diverse range of ages and ethnic groups." they're for age 45+ at the mo, concentrating on black men generally and white men with family history of prostrate cancer. That appears to be the angle they're using to get them taken up and proven by the NHS and they're claiming that will be very low cost.

Re this opinion which seems quite sensible at first glance..

"NHS is a long way from ordering any their PSE tests due to factual requirements for the tests to be proven via genuine clinical trials involving 000s of people across a diverse range of ages and ethnic groups. Those trials have to be monitored and validated and that takes a long time."

In yesterday report they brought up the Transform Study and thought it a great idea but at the same time the authors encouraged the NHS to pilot evidence based answers such as reflex testing themselves to push them forwards. They thought Transform good for directing the pathway forward but that evidence-based steps can save lives now which opens the door to acceleration of the PSE test etc.

Nice chart. Tungstens through the roof.

Well that's quite promising for todays ECR then as now they've bought a production kit and gold's booming even harder. Are you expecting a return to 4.4p Zebbo? That'd be nice.

Advfn posters believe the same so whether placing or not sentiment will lead to selling into spikes still imo. For myself will wait and see.

Hope you're not trying to play the victim here new that would be awfully boring of you. I said I was offended by your insult not your general reply.

Did note though that even you believe they'll have a placing before the end of Q4 whereas they stated they were working on funds running out by Q4 so already you believe they'll last another three months which is a result of sorts if so.

Thats the trouble isn't it Newuncle its just your opinionated opinion. You may be right but if they've downsized and had growing private sales here through BUPA etc and in the USA with the insurance co's picking up the tab as previously reported perhaps things aren't so dire anymore.

Take great offence by the way at your pathetic keep telling others comment as what I posted was NAI DYOR to make it plain I wasn't sure.

Reading through the interims they don't say they'll need a placing they state they have to right size the business else they'll run out of their cash runway by q4.

"Having been in this business for six months now, I can safely say it is a good business with excellent technology assets and with real and lasting sales potential, but it is carrying a potentially crippling overhead. As a result, based on the Directors' assessment, with the organisation and premises it has today, the current cash is only forecast to extend until Q4 2025.

Therefore, the immediate plan is to 'right-size' the business, reduce the fixed overhead and pivot our emphasis more towards growing the PSE test sales in the USA, whilst maintaining our core technology competency in the UK. With a re-alignment of costs and an influx of funds either through non-dilutive deals and/or a timely capital injection, the Directors believe the business can thrive and create sustainable and increasing shareholder value."

Its now 2 weeks into Q4 and no placing? We know sales are growing monthly they reported that in the interims with June beng their best month yet so with growing sales and right sizing how sure are we they've comee close to needing a placing?

I'm not so sure, reckon the bears'll be convinced obviously but for myself having sold a few a bit higher have bought some back on the offchance they've started to turn things around by now. NAI. DYOR.

Not thousands of machines-30 machines at an average cost of £1M so a slight error on my part there imo. Apologies.

Costs for MRI given as £199 though they'd have to buy thousands of machines to cope at prices from £300K to several million UKP's and biopsies are given at £495 and £725 for more complicated biopsies so £250 for a far less intrusive experience comes out well imho.

https://www.prostate-cancer-research.org.uk/wp-content/uploads/2025/10/Prostate-Cancer-Screening-The-Impact-on-the-NHS-Report.pdf

I have OBD's offering given as one of three and its the most sensitive secondary test after a positive PSA test. Its the one strongly recommended which is pretty good imho.

They allow £250 for the secondary test in the report so considerably cheaper for the NHS than for private..

"Recent advances in diagnostic technologies offer the potential to improve the accuracy and efficiency of prostate

cancer screening while reducing unnecessary interventions. These innovations span improvements in new and

improved PSA-based blood testing (reflex testing), AI-supported imaging and integrated diagnostic workflows.

Reflex testing refers to an automatic follow-up blood test that is performed when a man’s initial PSA result

exceeds a defined threshold. Using additional biomarkers, these tests help detect clinically significant cancers,

reducing unnecessary MRI scans and biopsies.

One such development is the Stockholm3 test, a blood-based diagnostic that goes beyond the standard PSA

measurement. It combines plasma protein biomarkers, genetic markers and clinical data – including age, family

history and prior biopsy history – into a risk-prediction algorithm. Intended for use in individuals with a PSA level

of at least 1.5 ng/mL, Stockholm3 provides a score indicating the likelihood of prostate cancer, with a sensitivity

of 92% and specificity of 33%.33 The test has shown promise in reducing the number of unnecessary MRI scans

and biopsies by more accurately identifying men at higher risk of clinically significant disease.34

Another innovation is the EpiSwitch PSE test, which is administered alongside the PSA test. It analyses five

epigenetic biomarkers and integrates these data with the PSA result to improve diagnostic specificity.

The manufacturer reports an overall sensitivity of 94% and a specificity of 97%, suggesting strong potential

to reduce false positives and minimise the need for further diagnostic procedures in low-risk cases.35

A third promising blood test is Proclarix, which measures a panel of protein biomarkers alongside a software

algorithm that incorporates the patient’s age to generate a personalised risk score. The test has demonstrated

a 95% negative predictive value, meaning that it can reliably rule out clinically significant prostate cancer in

low-risk cases. In retrospective clinical studies, Proclarix achieved a 90% sensitivity and a specificity of 43%,

significantly outperforming the PSA test.36

Didn't get that from the accts LOTM got it from the 28th Jan RNS where they were still claiming they exercised the option already..

"Howard White, Executive Director of HUI and shareholder and director of Ohrid Organics Ltd, commented: "With the addition of a new trading contract, Ohrid Organics DOO is seeing a notable boost in profits, enabling the company to repay its obligations to HUI. In the near term, it is projected that improved harvest yields will drive revenues up by one-third."

Why was Howards co. paying back its "obligations to HUI" if HUI now owned 49% of the co? Thought they only had to be repaid if the option wasn't exercised. Could see they were doing one thing and saying another so sold. Been waiting on their excuse for not "fully exercising" their option to claim their half of the profitable and growing co. ever since and yesterday that excuse came so releasing my outburst.

Will leave holders to it again now and hope they do make a success in the ME or at least have enough positive sounding newsflow to let current holders out at a profit.

OBD's PSE test is in the report. It's listed as one of three further tests and is the only one strongly recommended due to its very high specificity rates.

This'll likely be the push Rushi et al will make as they attempt to sell it today (imho)

PSA test alone only gives 32% accuracy -ie only 32% of positive results actually have prostrate cancer that why its suggested non symptomatic positives have a 2nd test before biopsy or MRI so saving the NHS much needed funds.

https://www.94percent.com

Articles ok imo. Its always been a case of first it's the cheap PSA test then for men who show positive on that one with no obvious symptoms then its the PSE test to prevent the cost of unnecessary and very expensive biopsies and MRI's.

PSE will be part of the process not all of it.

Doesn't Rishi represent OBD?

TTrue dat. Not only will it be major funds incoming but could well be enough revenue security for banks to lend to them.

OO paid HUI back in Jan SC. Seemed no reason at the time as HUI once again was claiming to have exercised the option. Believe they've been stringing investors along ever since whilst they find an excuse to do this.

All of OO's newsflow is extremely positive do you really think Howard was going to honour his word and let HUI investors have 49% for £600K odd (55M Hui shares)?

Personally doubt the Middle East .clients have said anything. They're just trying stave off an investor revolt. Probably work for them but still makes one want to puke when they dribble on about how the EU has scammed them.

Thanks for the reply Talkingsense. Like the idea of there possibly being a mine there too. Was thinking all that alluvial has to have a source somewhere close. Just no ones drilled properly I guess?

Hopefully their $1M will turn up soon then as that should be a boon for drilling.

Are these planning to search for the source of this alluvial gold? See they've mentioned gold in hard rock as well as gravel wonder if an actual mine is likely to be on the cards one day?