Member Info for OAPK20

Either say what your mystery project is or people will just think it’s just an attempt at propping up the share price by someone who says they have contact with the company.

Keep em keen though

“There is no suggestion anything like this has happened with Ciz”

RNS Number : 8524I

Cizzle Biotechnology Holdings PLC

10 August 2023

“The next steps are to finalise standard production and operating protocols and to commence clinical trials that should lead to an accredited Laboratory Developed (LDT) test for launch initially in the USA”

RNS Number : 2304I

Cizzle Biotechnology Holdings PLC

26 March 2024

“ The Directors believe that the new antibodies from this development programme should extend the range and proprietary rights that the Company has for detecting the CIZ1B Biomarker.”

“ Key anticipated milestones will be the production of a final antibody to accredited quality standards, other design and testing work, IP protection and progressing regulatory matters. ”

Must’ve been a lucky find. But then the LinkedIn posts appeared after the information of the US company was fed in to Telegram.

How many “PI’s” searched for new companies in Texas as part of their reading about CIZ. Such an obvious search is it?

I didn’t until it was posted here for the outsiders.

Who was fed that and by whom? That just coincided with a nice rise in SP before the Placing announcement nicely.

Whoever “found” that info didn’t find it the day company was registered or if they did sat on it.

So remember when you’re looking at any new share to trade or invest in to search the database in Texas for any new company registrations DYOR. Unless you’re an insider lucky enough be invited to partake in placings. (Not many PIs have that type of funding available)

Widglide. I’m sorry.

Hope it works out for you. I was lucky at my entry point. Derisked now but this is in the hands of the Placees and pumpers now to get a decent flip price until the next placing if it gets to that point.

A lot of angry PI’s reducing (< 4%) See how angry they get. Placees at 2p are going to have to pump hard to get above water.

Al is going to have to go on the Ramptastic interview circuit and ramp his self silly or those Placees might not be as generous at the next cap in hand round (IF it gets to that point)

CDT is up

Good luck. Hope you're pumping to your twitter followers too. Get this flying.

Did you take part in the placing ?

Would be a shame to pump a placing then pump it into another FAB. Hopefully others remember

Pump harder Chris. Placees still underwater. Pump pump pump pump

Admission will become effective and that dealings in the New Shares on the Main Market of the London Stock Exchange will commence on or around 11 April 2024.

Company will need to help the pumpers with RNS messaging now so they can all bail at 2p or above.

Wonder if they’ll pump it high enough for Warrant conversion 😁

Look who’s back.

Pump Pump Pump

Good luck

Derisked NT to sell now. Placees trying to exit too at breakeven. Needs volume and the company needs to gain investor trust amongst the PI community. Too many locked in at the last big spike and now new holders shafted on the latest rise.

There's only Insiders and Outsiders. Us outsiders are the mushrooms - Kept in the dark fed on dung.

Be on the mobile Tech waiting to be told what to say

VV it’s on Directors talk. If it’s pre recorded then questions need to be answered because that platform was brought “inside” if it was t done live

Cheers just saw it was the Heading

I didn’t ? Maybe redirect that Jace

Pre recorded or live ? Released 16 mins after RNS so questions to answer ?

https://www.***************************/cizzle-biotechnology-to-raise-0.62m-for-scale-up-of-key-antibodies-and-reagents-video/4121149042

Said all along they weren't selling CDT shares at a huge loss. (Given the placing has occurred they, as in CIZ might get desperate)Those that inferred it constantly know though.

Placing is a proper slap in the dish. Typical micro cap behaviour. E3 Fund couldn't have been keen to provide the £500,000 drawdown (which was fixed at 2.1p for those suggesting it could have been less). Company said they would need at least £1million so more pain to come.

1. Why NEW antibodies ?

"The Directors believe that the new antibodies from this development programme should extend the range and proprietary rights that the Company has for detecting the CIZ1B Biomarker."

This was interims 28/09/223 - ""We have now expanded our range of specific monoclonal antibodies for CIZ1B and as recently reported we are now deploying these on a high throughput laboratory platform provided by Bio-Techne, a $12 billion market capitalised life science and biomedical research group. Bio-Techne have worked closely with Prof Coverley's research team at the University of York and, having completed a successful evaluation programme, we are now able us to accelerate our clinical trials programme, initially in the USA."

So why new antibodies? Why a new Supplier ? Are they an improvement, an addition for detecting additional cancers or have CIZ and the team found the previous monoclonal antibodies to be inadequate?

Previous cost for Monoclonal Antibody & Reagent production - £30,000

Clinical samples - £25,000

Kit development and Clinical trials - £230,000.

So is it increased costs "to enter the scale-up and manufacturing phase for the main components of the Company's proposed commercial test for CIZ1B."

That is the majority of the placing swallowed up. Minimum £285,000 - £350,000 (or even more)

2.Patent - previous costs £10,000 - So how much more to pay ? Is it a fresh application ? My view remains Patent grant is a long way off. (13month at least by USPTO or hopefully sooner for the current Application Number 18/188,958) Minimum further expenditure possibly £10,000 - £15,000. Or more ?

3. York Lab support costs - Prev expenditure £50,000 - So maybe another £50,000 - £60,000

4. Development of LDT Certified Tests - £25,000 - 2 YEARS AGO - How much still needs to be spent ? Another £25,000 - £35,000. Even more ?

5. Marketing and overheads - prev expenditure £20,000 - How much are they paying Mr BB and paying to set up the US co in Texas - Minimum £20,000 - £50,000 possibly more ?

6. Salaries - £20,000 - has that stayed the same or is there higher expenditure since 2022 ?

7. Additional research - Prev expenditure £40,000 - So how much has been spent researching the "NEW" antibodies ? Minimum £40,000 - £100,000 possibly (since 2022) ?

All in all does it really sound now like CIZ have a test ready for clinical trials or are they still developing a LDT test that actually works ?

Finally the post on another platform about insider in

Green doesn’t CorePath buy the “ingredients” from CIZ then do the rest with CIZ taking 15%?

Neilin is surprisingly quiet after his recent 900,000 purchase. Must be on the mobile to Al.

Let’s see how quickly the clinical trials actually start.