Member Info for Num4

Instead of a full blown licence for SDC-1801 we may get a shared ownership and costs through the PI trial. Would certainly be a good outcome, shared risk for any licensor, shows belief in our product. Probably the right thing to do for shareholder value.

Hey Thoth,
I would have agreed that it was a big gamble a few years ago, but these last few months it doesn't seem to be - we are in effect following the big money from the HNWI and trusting the proven success of the BOD with these in demand compounds.
Doesn't feel.like a gamble at the minute. Biggest risk is we run out of Wotsits.

Ah they have reported the closing spread. Nice work MM.

James what L2 you using? Advfn has the spread at 7.4 - 7.70 at time of trade of16:16:18, 29seconds later it was 7.6 - 7.8.

Cobra, there is a few more, all delayed, not looking into it that much, we all.know what is coming.

Just noticed the 7.5p buy for 500k shares. Another Stella it is! A few more in there at 7.6 and 7.5 for similar amounts, all delayed publication according to advfn. The tide has turned for next week..

I was certainly the same Citizen, alerts setup on chk1, tyk2, sar-20347, sar-20351, CCT244747, IL6, sar-t29, aurora+flt3 to name a few.
I found the best articles not on the technical but on Tim speaking freely, whether it be video, audio or text, take away the awkwardness and you've got a genius, now being proven. There is a pdf somewhere of him and Robert Plenge having different views on tyk2, this was a great insight into his integrity, soon it will be Robert Who...

I've stopped the research into Sareum and their compounds, bit of a milestones after so many years, I think the compounds will now speak for themselves in clinical trials. Whilst I appreciate all the links, especially Citizen who has certainly taken the baton on, I've just stopped reading them - no offence Citizen.
No research article can change the path we are on with these compounds, IL6 receptor, TYK2 inhibition, JAK-STAT pathway it's all relevent and you'll find information forever more - do we need anymore validation, back in the day we would scramble for this stuff as it was that new in the world of autoimmune treatments it justified spending ~£3-7k tor a million shares. Nowadays I'm quite content that I can sit back and watch this unfold without any further research.
Even when Sareum don't exist as a company I can still follow these compounds through their development and make further investment decisions, as we all can, even if your just getting in now. 2 of the most intelligent people you would ever meet have designed drugs over an 8year period, you've got an opportunity to piggyback on that success - the HNWI's have done so and this is an opportunity you won't get again. I'm a firm believer in, you get out what you put in, but this has gone to a different level now albeit your only a good investor after you've closed a positive position. 7p, cheap as chips. Good weekend to all.

Thoth, you'll need to share to insight into charting when this is all.said and done, I fancy a go at trading for a very part time living. Yes, I'm building up to that book you've previously mentioned. Quite busy this year as you know and now in the middle.of an extension, funny that the roof will.be complete tomorrow, just as the Sareum roof gets blown off.

Silver, I took the rough with the smooth and should be over there alot more next year. It's in Agia Napa.

Thanks Jon! It's nailed on with these investors now.in play, they're just getting started.

Disagree, subjective. Most long termers are well there with a cherry on top. We just realised they are offering a much bigger portion.

Regarding buying property abroad, I also bought in Cyprus back in 2007, slightly different views than Silver who sounded like he got sold on empty promises. I think you need to treat it like any investment, hang in there, hold on to it, it will increase in value and you have more options available to you. Take the rough with the smooth and enjoy it as much as you can. Like shares don't sell when it's at a low. I now rent mine out on Airbnb, and managed to get over every year since, even last year.
Don't get sold, DYOR, remember why you bought it in the first place.

Unless the loop hole for the 5mill funding criteria can include warrants not yet issued. It is, after all funding just sitting there.

Everytime they drop the SP like this morning I panic and think to start selling..NAHTTTTTT...

Yes the legal costing had crossed my mind, I think you can agree that this is not the normal way to raise funds. Normally we have a once a year, discounted placing. We are seeing 3 premium placings with HNWI's over a short time.
It's great shareholder value and Tim looks to have grasped the AIM market, we knew it was in him but he's been too busy on the science.
In the past I've always hoped that this was the last placing, now I'm looking forward to more premium placings by the investors.

The chart for Sareum historically is a slow drop over time based on no news being released and then putting all information in the results. This has annoyed the lth in the past.
For the HNWI's to invest they would certainly not be happy with this slow trickle down and I'm sure they could see that pattern previously.
The presentations by Sareum show what news is coming and we've had it confirmed a few times now it's Q3.
The latest million pound drop was a curious one, what exactly is that money for, is it going out as quick as it's coming in.. I hope all is revealed very soon, the AGILE trial is taking longer than anticipated but it could all come as 1 RNS, first patient dosed in trial with partner announced.
We certainly have something here and the new high net worth investors give huge confidence in holding for a while longer.

For a person with severe COVID-19 who requires oxygen, I would definitely give dexamethasone. In someone who has rapidly worsening oxygen requirement and has blood tests that show increased inflammation, I would combine dexamethasone with either an IL-6 blocker or a JAK inhibitor,” he said, adding that no one knows which would be the best option.

“A head-to-head trial would be extraordinarily informative,” Dr. Gandhi said.

https://www.gastroendonews.com/Web-Only/Article/07-21/JAK-Inhibitors-IL-6-Blockers-for-COVID-19/64061

It has been CST-1 for a while, long before our SDC-1801 was successful in lab studies.

https://www.nature.com/articles/d41586-021-01839-6

More support for tyk2 inhibition across a range of autoimmune conditions.

No hope was correct Ahfam, 2p was a pipedream and 5p was a milestone for slicing for many. Those days have gone and it's purely based on COVID imo. Whilst a "side play" it has almost become the play of dreams. We could have revenues before autoimmune hits a trial. The pressure is well and truly off for this investment, I just hope Tim and John are still working from home and wrapped in bubble wrap.
Busy AGM this year that's for sure with MG1 parked at the front entrance.