SCC79 Annual Scientific Meeting & Showcase13 Dec 2025 15:44
Please join Alba Cico, PhD. on Tuesday, December 16 during Session E: Emerging Technologies to discuss From Gut to Skin: A postbiotic approach to improve skin condition and holistic well-being.
Session E, titled "From Gut to Skin: A postbiotic approach to improve skin condition and holistic well-being," a presentation by Alba Cico, Ph.D. (Sederma), at the SCC79 Annual Scientific Meeting & Showcase. Sederma is a part of Croda Beauty.
Key Concepts from the Session
The presentation focused on leveraging the understanding of the "gut-skin axis" and postbiotics as an emerging technology in cosmetic science.
The Gut-Skin Axis: This is a complex, bidirectional communication network between the gut and the skin, which modulates systemic immunity, inflammation, and metabolism, ultimately affecting skin health.
Postbiotics: These are bioactive compounds produced by beneficial bacteria during fermentation. Unlike live probiotics, postbiotics consist of non-viable microbial cells or their metabolites, which minimizes safety concerns related to live bacteria while still offering functional benefits.
Benefits for Skin: Postbiotics have shown promise in reducing inflammation, strengthening the skin barrier, boosting hydration, and supporting the growth of beneficial skin microbes. They can be considered a novel alternative therapy for immune-related skin conditions.
Holistic Well-being: The session highlighted a holistic approach, linking gut health (via postbiotics) to overall skin condition and even mental wellness through the brain(s)-skin connection.
Zenakine™ Innovation: The session specifically discussed Sederma's postbiotic innovation called Zenakine™, derived from precision fermentation of Lactobacillus rhamnosus GG. Zenakine™ is designed to boost NAD+ synthesis and upregulate longevity genes to revitalize mitochondrial activity and restore metabolic balance in the skin, addressing the impact of stress and aging on skin health.
Emerging Technologies Discussed
The session showcased how emerging technologies in the field are enabling these advancements:
Precision Fermentation: The use of precision fermentation to develop specific, stable, and effective postbiotic ingredients like Zenakine™.
Advanced Sequencing and Bioinformatics: While not explicitly detailed as part of the talk, the broader field relies on advances in high-throughput sequencing and bioinformatics to understand the complex gut and skin microbiomes and how they interact.
Biotechnology and Neurocosmetics: The application of biotechnology to create ingredients that work through neurocosmetic pathways (communication between the brain and skin) to improve well-being and skin appearance.
This approach suggests significant potential for developing innovative, comprehensive dermatological treatment strategies and next-generation skincare products.
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