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March 29, 2016 7:30 am
Chi-Med taps Nasdaq for $100m to help break innovation drought
Andrew Ward, Pharmaceuticals Correspondent
A $100m Nasdaq flotation has given a fresh impetus to efforts by Hutchison China MediTech to produce the first drug to originate from China for decades.
Christian Hogg, Chi-Med chief executive, said the initial public offering, which was completed last week, would support work on two cancer drugs being developed in partnership with AstraZeneca and Eli Lilly as well as several others at earlier stages.
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The company, which is 65 per cent-controlled by Li Ka-shing’s CK Hutchison group, is the second Chinese drug developer to list in New York this year after Beigene raised $158m last month.
China has not produced a new medicine for the global market since artemisinin for malaria in the 1970s — a breakthrough for which chemist Tu Youyou was awarded a Nobel Prize last year.
Mr Hogg said Chi-Med could end this innovation drought if clinical data due this year from a trial of savolitinib — a kidney cancer therapy co-developed with AstraZeneca of the UK — was good enough to file for approval with US regulators.
“The Chinese biotech industry is evolving and we are starting to see companies come through,” said Mr Hogg, a Briton who has run the Hong Kong-based company for a decade. “We are in China but we are developing for the global market.”
Another drug called fruquintinib for colorectal cancer, co-developed with Eli Lilly, is also in late-stage development and five others are in earlier stage clinical trials.
One of the most promising — a treatment called HMPL-523 for blood cancers and rheumatoid arthritis — is a potential rival for blockbuster drugs including AbbVie’s Humira and Imbruvica.
Chi-Med’s New York IPO adds to the listing it has had on London’s junior Aim bourse for the past 10 years. Mr Hogg said UK institutional investors would remain the “foundation” of the company but he admitted to frustrations with Aim.
“The main reason for the Nasdaq listing is to get in front of specialist biotech investors who can value the Nasdaq listing is to get in front of specialist biotech investors who can value the company properly,” he said. “The issue with Aim is liquidity. Nobody trades shares. As a result, there’s no analyst coverage. When you have a big investor base they need to be able to read analyst research.”
Chi-Med raised $101.25m through the sale of 7.5m American Depositary Shares at $13.50 each. The IPO was oversubscribed but priced at a discount to the London share price, reflecting the difficult market conditions which have sharply slowed the flow of IPOs this year.
Dozens of European life science companies have listed on Nasdaq ov