Member Info for miavoce

Trish's next scan is in 12 weeks - tumour should be virtually gone by then if reduction continues at same pace.

This is exactly in line with what I expected. The tumour shrank approx 35% in the first 10 weeks to start of Nov (1st dose was mid August) so shrinkage is approx 3.5% per week. It has now shrunk a further 15% (of original tumour size) in the 4 weeks since last scan.

Thanks so much for thinking of me xx

I tried to update yesterday but as you say, the site was down so I couldn't.

More great news, just incredible. My tumour has reduced by another 15% so it is now 55% smaller than before the treatment started.

The oncologist is absolutely delighted especially as this vaccine is his baby. Everyone in the clinic was buzzing about it yesterday, I suppose it is a massive breakthrough for cancer treatment and it gives hope to many for the future.

I have a 12 week gap vefore the next vaccine and scan now but fir today I am floating on air.

To think that this time last year I was sent to the oncologist for palliative treatment having been told by my surgeon that things didn't look good.

I'm feeling incredibly lucky that the planets aligned and placed me in the right place at the right time. Long may this feeling continue.

Thanks again for thinking of me, so much appreciated, hope you are well yourself xxx

If I recall correctly from the recording - LD mentioned at the AGM that they had checked with the Nomad about the patient posting on the Macmillan site and the Nomad said it was OK.

The Macmillan site downtime was flagged by another poster a couple fo days ago. Expected to be back online 7pm.

ere you go Riga

https://community.macmillan.org.uk/cancer_types/head-neck-cancer-forum/f/updates/248889/immunotherapy---cancer-vaccine-trial#pifragment-13906=3

44 mins ago from patient 1

Morning, I see my consultant on Monday so I'm hoping he has the results then. Fingers crossed

Trish x

You see to have set the SP alight !

Fair point BS

I feel it is fairly certain now that patient 1 has been asked to hold off from sharing the results of her latest scan. She seems to be an open and forthcoming person so the fact that the hasn't yet shared her results despite her earlier response to Welly Walker would indicate that she has indeed been asked to hold off. Lets hope it isn't too long before SCLP make an official announcement (I would expect that the other 2 patients in cohort 2 have now had their first scan as patient 1 had hers a months ago.

16 trading tays till Christmas. One one of those days we will get the Modi1 immunogenicity and safety update plus no doubt they will update on patient responses. Assuming that is goo the SP will be strongly up from there. In the meantime the usual drifting around will occur.

Thanks Chester18, would be good to get an update by year end on Scib1, lets hope they can stick to that timetable.

I don't remember Scancell saying we would get a SCIB1 update by year end, when was this mentioned ? I do remember them saying (more than once) that we would get an update on Modi1 immunogenicity and safety before year end (they repeated this at the AGM). I expect we will get an update on the progress of the patients at the same time and maybe they have asked patient 1 to hold off on sharing her scan results until Scancell themselves have done their update (to give the Scancell update maximum impact).

£8-£12 imples a market cap of £6.5bn - £12bn.

If modi1 proves to be highly successful then it could generate future sales of £10+bn per annum. Add in Modi 2 and Modi3 and future potential sales could be £40bn+ giving an annual profit of maybe £20bn - £30bn, which would give a future market cap on a (pe of 20) of £400bn - £600bn.

Of course Scancell won't get to a point where it is making that kind of income because one of the big pharma's will come along an licence the Modi products or platform well before then - the question is 'what would they need to pay for it ?'.

Well to 'buy' a potential future annual profit of 20bn to 30bn they would need to pay big money - may billions in upfront and milestone payments, plus they would need to pay a decent royalty (say 15%).

With the above in mind I can easily see where a £8 - £12 SP could come from in the next couple of years.

ADVFN : 'Hold my beer...'

chilpill1, Lindy said they would probably just miss the end of this year for the Covidity results so they will be published in Jan.

Might just be me lofas, but I have no idea what you last post means - can you enlighten me :-)

Accelerating Modi 2 or 3 would be a good use for some of that money.

Proce holding up despite selling. Must be a decent sized buy being worked in the background ?

Hi chester18, I'm looking forward to you being pleasantly surprised :-)

chester18 - if we keep getting good news on Modi1 i.e. news indicating that it is working, I believe we will quickly move into the £1bm mkt cap bracket (maybe by end 1Q 2023). If it works Modi1 will become one of the most valuable drugs ever, and the Moditope platform will be worth many billions. IMO there will quickly be a bidding war between the biggest Pharma's....

Maybe this sounds fanciful, but if Modi1 does what it says on the tin it is highly probable.