CRS13 Feb 2024 16:27
Faron’s investigational intravenous (IV) interferon beta-1a therapy, Traumakine, is being developed in collaboration with the Fred Hutchinson Cancer Research Center in Seattle, Washington, for the development of neurotoxicity related to cytokine release syndrome associated with CAR-T therapy.
Just wondering how big is Faron seeing their potential market? Poolbeg Pharma is seeing a nice market opportunity in CRS.
“12 February 2024 - Poolbeg Pharma (AIM: POLB, OTCQB: POLBF, 'Poolbeg' or the 'Company'), a biopharmaceutical company focused on the development and commercialisation of innovative medicines targeting diseases with a high unmet medical need, today announces that independent research[i] [ii] conducted on behalf of Poolbeg confirms a >$10 billion market opportunity for POLB 001 in Cancer Immunotherapy-Induced CRS as an orally delivered preventative therapy. Cancer immunotherapies have been approved in rare and orphan blood cancers and so the Company can see potential for POLB 001 in one or more of these cancer types. POLB 001 in cancer immunotherapy-induced CRS will be developed alongside Poolbeg's existing portfolio of assets including its influenza programme; its AI drug discovery programmes; and oral delivery of GLP-1 for obesity and other metabolic diseases….
…The size and attractiveness of this market has encouraged the Company, as the field of cancer immunotherapies, including CAR-T and BsAb, is burgeoning and is expected to grow to US$100bn - US$140bn[iii] by 2030. CRS occurs in the majority of CAR-T and BsAb treatments frequently impacting >70%[iv] of patients and cannot be predicted. All grades of CRS can lead to extended hospital stays, causing an estimated US$5.5bn[v] of hospitalisation costs to healthcare systems, and further indirect costs through patient treatment and follow up.”