RE: Ventilator Pneumonia9 Apr 2020 20:07
“Randomized, Double-Blind, Multicenter Phase II Study to Evaluate Efficacy and Safety of Intravenous Iclaprim versus Vancomycin in the Treatment of Hospital-Acquired, Ventilator-Associated, or Health-Care-Associated Pneumonia Suspected or Confirmed Caused by Gram-positive Pathogens.”
This poster presented data on outcomes related to treatment with iclaprim compared to vancomycin, a standard of care treatment for Hospital-acquired bacterial pneumonia (HABP), ventilator-associated pneumonia (VAP) and healthcare-associated pneumonia (HCAP).
Patients who received a low dose of iclaprim, a high dose of iclaprim, and vancomycin had a clinical cure rate of 73.9%, 62.5%, and 52.2%, respectively. Under the same treatment regime patients had a Day 28 mortality rate of 8.7%, 12.5%, and 21.7%, respectively.
These data show that iclaprim had high clinical cure rates and relatively low mortality rates among patients with HABP, VAP, and HCAP.
https://www.motifbio.com/news/announces-results-of-two-posters-on-iclaprim-at-id-week-2015/