Member Info for Kaneonaim

No tyke couldn’t find anything that says they’re presenting there. I did find this though which is interesting considering we signed agreement in October with them to explore other indications for Gam

Laura Towart: Vivan Therapeutics Was Named 2025 London Life Science Company to Watch

Laura Towart, Founder & CEO at Vivan Therapeutics, member of 100 Influential Women in Oncology, shared a post on LinkedIn:

“It was an incredible honor for Vivan Therapeutics to be named a 2025 London Life Science Company to Watch by MedCity and London & Partners.

It was a great opportunity to reconnect with the community and meet new prospective investors and partners at the Bench to Business London Showcase yesterday at London Life Sciences Week! Thank you to the organizers for this fantastic opportunity to be featured. I especially liked the panel on ‘The Impact of AI on Biotech Investment: Adapt or Differentiate’. ”

Tweet on a Saturday

Year in Review 2025: Neuro-Oncology | Vumedi https://vumedi.com/video/year-in-review-2025-neuro-oncology/?t=59 via

@vumedi

@TuftsMCNeuro

https://www.vumedi.com/video/year-in-review-2025-neuro-oncology/?t=59

yes it is worrying. sarah rumler, medical college of wisconsin (responsible party) is listed so at least we know them.

the sad thing is that the select few insiders will know exactly what’s happening but us personal investors are literally treated like mushrooms. kept in the dark with ****e thrown on us every now and then.

it’s mind boggling why tb has just gone completely off the radar and couldn’t care less about normal personal investors.

He’s just using loopholes advised by his that are meant to be our company brokers. He has a hold over the company as he would claim nobody else would fund us. Hence the reason he is releasing as little information as and when it suits him to enable the company to still look undesirable. Which is what is most annoying as the ceos jobs is the complete opposite. If anyone remembers when we had a ceo David smith they would remember his interviews how he was the face of the company never shying away from giving information even when it wasn’t good(when we needed to reapply for stonechecker fda) he would always answer email questions just the complete opposite of how Trevor is running us into the ground.

No because he’s the ceo of braveheart or whatever he’s decided to call them now so he’s basically voting for himself

Yes agreed with him stepping down and employing a real ceo who would help promote the company for all shareholders this would probably rise 200 percent

Tyke

This is a journal entry

TRLS-03. GABRIEL (Gallium Maltolate for Better Outcomes in Relapsed/refractory Atypical Teratoid Rhabdoid Tumor and High-Grade Glioma): A Phase 1 Clinical Trial of Gallium Maltolate for the Treatment of Pediatric Patients with Relapsed or Refractory Pediatric High-Grade Glioma (including Diffuse Midline Glioma) and Atypical Teratoid Rhabdoid Tumor

Sarah Rumler , Mona Al-Gizawiy , Jesse Cramer , Jennifer Connelly , Kathleen Schmainda , Ke Yan , Shama Mirza , Christopher Chitambar

Abstract

Brain tumors are the top cause of cancer death in pediatric patients. Two with highest mortality are relapsed, or refractory, HGG (including DMG) or ATRT (rHGG/rATRT). Iron plays a key role in many tumors’ essential cellular processes. HGG cells have transport proteins that preferentially take up ferric iron [iron (III)] via transferrin receptors (TfRs) to drive cellular proliferation. Gallium is a metal in the same period as iron, and so similar to transferrin-bound iron (III) that it is taken into the cell via TfRs, acting as a “Trojan horse” to disrupt essential tumor processes, causing cell death. Gallium maltolate (GaM) is a compound stable in solution and orally bioavailable. As previously described, our work with pediatric HGG and ATRT cell lines showed, when compared to controls, decreased oxygen consumption and increased apoptosis with GaM treatment; animals with ATRT and HGG xenografts treated with oral GaM had significantly higher median overall survival, and these tumors grew at a significantly slower rate. The animals also had excellent maintenance of quality of life observing behaviors such as social activity and appetite. In our ongoing Phase 1 trial of oral GaM for adult patients with recurrent glioblastoma, GaM has been well-tolerated without significant side effects. Thus, we hypothesize GaM can be safely administered enterally to pediatric patients. This is a prospective, single-arm, open-label phase 1 study to determine safety, tolerance, and pharmacokinetic data of an enteral formulation of GaM in pediatric patients with rHGG or rATRT. Aims: i. Determine the maximum-­tolerated and recommended phase 2 dose of GaM, ii. Determine the safety/tolerability of GaM, iii. Describe anti-tumor effect, and iv. Obtain quality of life data. We believe GaM offers a new type of therapy with potential to improve dismal outcomes, while being less burdensome compared to most currently-used rHGG/rATRT regimens.

It’s not the same because the article goes on to mention this

In our ongoing Phase 1 trial of oral GaM for adult patients with recurrent glioblastoma, GaM has been well-tolerated without significant side effects. Thus, we hypothesize GaM can be safely administered enterally to pediatric patients. This is a prospective, single-arm, open-label phase 1 study to determine safety, tolerance, and pharmacokinetic data of an enteral formulation of GaM in pediatric patients with rHGG or rATRT.

So it’s a separate trial imo it’s just I’m not sure they’ve announced it. Unless it’s got nothing to do with Ibai other than the people organising it and the drug being used?

Have I missed an announcement of a phase 1 paediatric trial? Called Gabriel or have they not announced it yet? It says

GABRIEL (Gallium Maltolate for Better Outcomes in Relapsed/refractory Atypical Teratoid Rhabdoid Tumor and High-Grade Glioma): A Phase 1 Clinical Trial of Gallium Maltolate for the Treatment of Pediatric Patients with Relapsed or Refractory Pediatric High-Grade Glioma (including Diffuse Midline Glioma) and Atypical Teratoid Rhabdoid Tumor Open Access

Sarah Rumler , Mona Al-Gizawiy , Jesse Cramer , Jennifer Connelly , Kathleen Schmainda , Ke Yan , Shama Mirza , Christopher Chitambar

In our ongoing Phase 1 trial of oral GaM for adult patients with recurrent glioblastoma, GaM has been well-tolerated without significant side effects. Thus, we hypothesize GaM can be safely administered enterally to pediatric patients. This is a prospective, single-arm, open-label phase 1 study to determine safety, tolerance, and pharmacokinetic data of an enteral formulation of GaM in pediatric patients with rHGG or rATRT.

https://academic.oup.com/neuro-onc-peds/article/1/Supplement_1/wuaf001.100/8231139

Remember they have already told the market numerous times the results are good the problem will be if it’s the same untrustworthy board of directors that will try to take this forward if so the share price will stay the same or drop further when people realise the 5/10 x isn’t happening.

The only thing that will turn this around is is new bod who want every shareholder to increase value not just the select insiders.

Also aren’t we rapidly approaching our annual placements time that normally happens around now. In my opinion it’s how bad will it be this time. I’m guessing 0.0075

He became a director. He became an insider. He was shown what the plan is. The one that no regular shareholders get to see. He resigned….. that in its self says a lot . One day it will switch and you’ll understand this is a major scam like a lot of small cap companies it’s just difficult to see at the moment because you’re still in the denial stage!! All in my opinion

This will probably never see 1p again the next announcement will probably be them changing the nominal value to 0.0075 like they have notified then you’ll get the trail results with some pump interviews all for the placing flippers to flip there 0.0075 placing shares then when they’ve finished it’ll be dropped that they’ve done a huge placing taking shares in issue to over a billion but tb and family will still hold 30 percent . This is in my opinion what’s going to happen into the new year

Tb should hang his head in shame. This guy recently lost his wife and has done more pr than the stupid old fool has all year. How embarrassing that no official interview or statement from tb or any other directors of Ibai or whatever they’re deciding to call themselves. £100k a year for what???? Scumbag!!

Looking forward to see next how tb can destroy value further here with either a placing or cln. My money is on a placing at 0.0075

*hasnt

It wouldn’t be the first time a tb controlled entity has declared on time. I vaguely remember FAB not declaring selling some for a while after they had

Tyke what I have learned recently from the rns’s submitted for roughly 2 years now is they raise more questions than they deliver.

They haven’t mentioned what this updated products projected income is because it doesn’t have any, something that will be proven in a few months with the updated financials. If they have signed any new contracts they would have rnsed it.

The only certain thing approaching here is a cash raise and the only question is how will it be presented. A filthy discounted placing or a cln at a stupidly low price

In my personal opinion this is a scam designed to keep gullible long term holders thinking the pot of gold is just around the corner but in reality it’s not even close.

Do your research people and see what the board have been promising and what they have delivered to date. The only person here making money is the CEO whilst doing absolutely nothing no pr no interviews nothing.

Didn’t take him long to get fed up here did it.

Is that you presenting Max?

Probably getting his nappy changed and being fed through a feeding tube on day release from his care home twice a week to check his companies share prices

Hi everyone a bit off topic and I’m aware everyone is skint here lol

But my nephew had rare testicular cancer and is running a 5k with his mum and sister for Great Ormond Street Hospital and looking for sponsorship his goal is £500 and he’s already at £230 so any help is appreciated

https://race.gosh.org/fundraisers/Jasonsrace