Member Info for JonBell

That’s correct. The rest of the data at that time didn’t reach for the sky, however the unmet need certainly looked good. Orphan fast track. There were a couple of guys from the States who came on here as they were invested in Sierra. We were banging on about them not pursuing it after the so called gangbusting, and I felt they gave some level headed analysis of the info we had on Chk1.
We were probably in the 0.8p spectrum and wishing it to hit its peak of 1.odd p we got to on announcement of that original deal with pronai. Warthog and Utah were here, banging the drum of negativity :)
Only my opinion, rather than take ridicule at the jam tomorrow notion, embrace it and invest what you can afford, little by little, it’s what some did back in the 0.3-0.8p range when we were getting delays to 1801 because of more tweaking to overcome resistance of some sort. We stuck with it, and made money. Personally I’ve been there, almost 50% in the red, but the market does what the market does, if you believe they have a half decent set of products then get invested and stick it out.

Apart from the shenanigans with the CTA approval, I’ve not seen much wrong with how they have managed their molecules, but that’s why I’m invested.

Love peace and harmony

So we see Uber confidence in the meeting, 2 mentions of people wanting chk1 , and to be fair, how confident is John Reader? “ get it into trials , and then we will see” . I’m putting £500 in a month , until I feel it’s reached it’s level. This may well be a terrific 5 year investment.

Happy and healthy Christmas.

Love peace and harmony.

An observation.
Unless we are in a period whereby our directors cannot trade, the fact that SP hasn’t bought since the latest RNS can be a concern.

A kind of paradox.

Love peace and harmony.

Nice post.
Our chk1 , how I remember was that when the cancer cell is trying to replicate but can’t and it’s screaming for help, the chk1 gives it an almighty kick in the nuts. Looking at anogenial (.?) it looks like chk1 gives it a punch in the throat also.

Tyk2 , how I imagine it, is like trying to take down a guy who is the leader of a pack of nasty dirty hobbits’ but doing so when holding onto his friend to his left or right. Ours is the one that sits right on the leader.

I’m a mere gas engineer, so I think in simple terms, so may be completely wrong on the mechanics.

Love peace and harmony

Just remember we are in the Kali Yuga. Stuff like the worlds richest man spending gross amounts of money on an app certainly alludes to that, in the meantime our kids will be swimming in vast amounts of our excrement soon enough and have a major battle with getting access to fresh water and clean air.
On the Elon note too, what a twiz, he gets a picture of himself holding a basin( not a sink) as he walks into the twitter hq and says , let it sink in. There’s no words printable to describe.

Anyhow, come on Sir Tim, let’s have the details of the license agreement please.

Love peace and harmony.

As far as we know from the data, our chk1 has a possible fast route to p3 for anogenial(?) cancer.
Awaiting cta confirmation and start of trials, for our tyk1 . It was only a few months between chk1 cta and on license.
Looks like someone got caught out with a stop loss yesterday.

Anyway, each to their own. Sir Tim and co know what they’re doing.

Love peace and harmony.

Probably a couple or a few months away now from a licensing deal. Come on the Sar.

Love peace and harmony

In agreement with that hypothesis. Why bother changing the fact that Sir Tim is based mainly in England? Feels like loose ends are being tied up.

Love peace and harmony.

For a bit of fun.

Todd Snider,

Talking Seattle Grunge Rock Blues (live).

Hey hey my oh my..

Love peace and harmony.

Hey Aber, not a bad shout. That’s my figure in my mind. £2bn mcap perhaps once chk1 in anogenial fast track orphan status and maybe other indications. Then our treasured tyk2/jak1 once in clinical trials and maybe end of p1 trials and then a good readout of data. Then a buyout.

Intraday is only there to test our patience. We have been here from 0.3p so keep holding on to those nuggets.

All my opinion of course.

Love peace and harmony.

At 11:22 for 893 is mine. Come on the sar, Haway the lads.

Love peace and harmony

We have a big pharma now with full control of our chk1 and a bit of dollar behind them to fund whatever trials they find best. P2.

CTA coming soon.

And it’s great to hear from you horse1.

Love peace and harmony.

Is hard word to spell at this hour. However, lest not forget that Sir Tim without stating as much,said that you’d practically need to eat the stuff to get some sort of result in the MTD.

The consolidation does whiff of a possible off shoot or amalgamation to a larger pharmacy imo.

Never mind the January blues, or February, there has been no news released which is negative.

Keep tight hold of those shares, ignore intraday , look long term.

Love peace and harmony

Always interested in your opinion.

Love peace and harmony.

Looking a lot like Sierra at the moment. We mentioned share consolidation at a AGM prior and it was dismissed by the board as not being apt, however we are now going to progress with it.

Bought into Sierra back when some lady bought a shed load of shares, and they had the warning from the American market that unless they had a share value of $1 dollar or more , then they would be unlisted. Now showing as a 100% increase on the investment.

Now Sierra are loaded with tutes. Gilead one of them. Albeit eyes on momo and let’s hope they succeed. It was a total curve ball from them to buy a compound back for $3m dollars or thereabouts whilst, as we say, gangbustering chk1.

The MTD has been mentioned by Sir Tim as being a good problem to have. Then suddenly we are going for a capsule formulation, rather than an oral dose. We have proved we are better than current antiviral treatments for Covid.

We have, as mentioned many times on here, gleaned the material input of a few millionaires. Perhaps they are not as impatient as lower spectrum investors, like myself, ha!

Then we get shorted to death and finally Parker comes good, buying in at three pence and a bit. Uber confidence.

Apart from my own twitchy bum and impateince ,there seems to be no need to sell up . At least not until we have a licensing deal for tyk2 in autoimmune and cancer. June we have been told at the latest.

Got my pedallo ready.

Love peace and harmony.

We’ve been here a while now. Personally only since 2016. Patience can send you mad if you let it. Look where we are now though. Chk1 potentially with other molecules in p2 trials ( when we bought in this was preclinical), and now two tyk2 molecules almost ready for clinical trials.

Sareum business model is to on licence in preclinical and / or early p1. This is sure to happen, so yes, sometime in 2022. People scoffed Sareum back then, claiming jam next year and nowt now.

Fortunately there are just over 1.6m of these shares stuck in my sipp, at not a great cost, round about 9k, and a few hundred thousand in an isa. I took some jam from the isa and am prepared to get to the finish line now. So holding tight and awaiting a glorious outcome. Fingers crossed , retirement looms at 57 :)

Hope you manage to stay the course warthog4.

Love peace and harmony.

Covid news, and trials not to start till mid 22, it feels similar to an earlier period in Sareums history, when we were informed of no news coming forthwith and we saw the share price drop, all the way down to the low thirty’s. Shorting it was easy back then as the price was already low as was the volume. Maybe this time it will be different as the whole set up of Sareum has changed, for the better, and any news of a positive RNS prior to next year would send this share sky high.

My shares are tightly gripped in my hand and it’s glued to the A45.

Love peace and harmony.

Looks like not only a way of biomarking an individual to determine if they are likely to benefit from Tyk2, but also a way to transport and manufacture a crystalline form and determine it’s quality.

A gut feeling says to have that patent is better than not having it.

As per Dr.Parker, we are heading to clinic.

It’s just a waiting game.

Love peace and harmony.

Not in a million years NUFC.

Haway the lads!

See you in the championship next year :)

Love peace and harmony.

Tweet is from jan 2019…….

Love peace and harmony.