Member Info for JonBell

Deal is imminent. Afham3 earlier was pretty spot on imo. 2 tyk2 molecules. Otherwise srra have eyes on taking it to market themselves. (Chk1) Big buying opportunity this next month. Good news incoming. This has been a well informed board. Thankfully not full of tosh. Love peace and harmony.

£250 purchase. Wish I could afford to invest more, but they all add up. We’ve got something good incoming. Have a nice weekend all. Love peace and harmony.

Jak2 usually brings on bone brittleness. No news on tyk2 resistance .

Absolutely Ahfam3. There is evidence that Sareum have already received payments from CHK1 in their final results, with once the phase 2 has recruited the cohorts and first dosed them, another one to come. Albeit 27.5%. Sareum have evidence that tyk2 is outperforming a marketed molecule in pre clinical studies. We�ve got formulation issues with a molecule that cured cancer in 10/10 mice, and fully granted, it may not be resolved. Perhaps some nano particle technology to deliver our molecule to the heart of the cancer could help. Oral or IV. How someone recommending the post of an impatient investor in a business model that is doing what it says on the tin, and producing best in class molecules, patented via the SKIL platform, could show any new investor to research where you invest, before investing. I�m clearly biased and feel it�s all going to plan. Love peace and harmony.

We are approaching the end of the development of our candidates. This is the time when the little things that happen matter. �Middle of the year� said Sir Tim, that could be from now until August. Or longer. It can be a matter of elimination regarding using nano particles to whom we have asked for assistance regarding aurora. We know it�s not long after selection that a license is delivered and remember this is their business plan. My apologies for ramping about it last year and getting it clearly wrong. Now we have heard it from the horses mouth, there can only be one way this sp is going to go by end of the year. Can someone link any bad data on our tyk2? Have your stock ready that you want to sell when the license or buyout comes. There isnt many mundane RNS left. Love peace and harmony.

To be held........? That�s the dream. The reality is it is in Lazio. I hope it�s got a big back garden. Love peace and harmony.

The preclinical development candidate to which Sareum regains rights has showed particular promise against a range of haematological cancer models including AML and Acute Lymphoblastic Leukaemia (ALL) with good tolerance of the candidate drug at the predicted therapeutic dose, and no significant side effects being seen. From the RNS today , the fact no significant side effects being seen is very good. However a couple of paragraphs down from that they are telling us that mtd hasn�t been tested due to the formulation aspect. We knew this already. However it�s an issue that must be resolved if it�s going to go on and go into humans. They�ve been proactive. As an investor it�s about being patient. My own thoughts are that a couple of months after tyk2 selection a deal will be announced. Of course I have a dream that Sareum will be bought out. And of course I know jack. My average is now the same as the mid price, so I�m neither at a loss or profit. It was more of a formality RNS today. Sareum is on the square. Here�s hoping the Renault Clio lasts out till the licence RNS :) Love peace and harmony.

�2500 trade is my last one. Hoping it�s a good price and looking forward to patent, candidate selection and license news to come by end of the year. Good luck all. Love peace and harmony

Aye, however 747 adds to 9, the most powerful number. 737 on the other hand adds only to 8. May be something, may be nothing on this quiet day. Love peace and harmony.

Patent been granted, John has spent quite a bit of time trying to resolve this. I�m not sure but I thought there was a hearing of such April just gone. After which let�s see if it gets the Tyk2 licence deal shifted on a bit quicker. Updates before end of year. Not sure if we will see the likes of 0.6p again unless something like Aurora doesn�t get fixed. Each to their own, 0.8p is cheaper than the day the NHS trials were approved for Chk1. Love peace and harmony.

Nabbed myself another grands worth. Nice price. Good luck all. Love peace and harmony.

Forget the daily intraday. Pronai were caught out to be dubious by professing their lead molecule was not all they made out to be. They realised they needed a Chk1 inhibitor to help their molecule. Our Chk1 has a quirky side arm to help with dosage levels, hence current results showing that in monotherapy and also in other indications. They have the best Chk1 at this stage out there, so let them get on with it, as this is Sir Tim and Johns business model, to spend resources in building the best molecule with the patent guaranteed, and then licensing that molecule. Tyk2 thus far has only shown to be a successful molecule. Sir Tim and John both have PhD�s, are no muppets, they both worked on IRAK the forerunner of Tyk2, and have worked for majors were testing is all about numbers and finance. This is their baby, and sometime this year, I reckon their hard work will pay off with a licence for tyk2. They want their molecules to be licensed by companies prepared to give them the full love those two have, they don�t want them to stagnate behind other molecules or lack of finance to progress. Pronai fit like a glove in that respect. I�m hoping Parker stops putting his middle finger up his own arse whilst in the shower, dreaming of non brexit, and is actually in negotiation stage. With him I�m not so sure. Maybe that�s my bias. What I like about this company is that�s it�s not built on flannel. It�s on the square, and it�s an excellent investment opportunity. Any investment from a hundred quid per month to a lumper is worth it here. Is my thinking. A downside, for me personally is that I�m not sure aurora will cut the mustard. But I�d like to have egg on my chin about that. Good luck all, try not to get sunburnt tomorrow :) Good to see you are still around horse1. Love peace and harmony.

News Release August 5, 2016 Carna Biosciences, Inc. Kohichiro Yoshino, President & CEO (Code:4572, Jasdaq Glowth) http://www.carnabio.com/english/ Carna Biosciences Announces Termination of Collaboration with Johnson & Johnson Innovation Carna Bioscience announced today that Janssen Biotech, Inc. is terminating the license agreement for one of Carna Bioscience�s small molecule protein kinase inhibitors for strategic reasons. Carna Bioscience had granted to Janssen an exclusive, worldwide license for the development and commercialization of the molecule in June, 2015. Upon termination of the agreement effective August 23rd, 2016, Janssen Biotech, Inc. will return all rights to develop and commercialize the molecule to Carna Bioscience. Carna Bioscience believes that the molecule remains promising and is actively seeking a new partner to develop and commercialize the molecule. The termination of the agreement will not materially affect Carna Biosciences�s 2016 financial results. Tyk2 went in preclinical studies July 23rd 2016, it may be nothing, but hopefully it is, and Jansen are awaiting for all relevant data from the studies before making a decision. The more Chk1 keeps performing, and fingers crossed, tyk2 shows promise at being best in class in the studies,then rather than a 300-400 million license deal for tyk2, it opens more premise for a takeover of a similar value so they get the 27.5% for Chk1 as well as the SKIL platform. Keep going with the no news, the only one we want to hear is the license deal and or takeover. Love peace and harmony.

Zzzzzzzzzz. 0.75p incoming.

Krone, you�re a good source of information ref the Agm minutes. Only my opinion, I doubt a licence agreement will be released in the interims. Regarding tyk2 it�s also in the hands of the acadeamia world also, there�s a strong feeling that tyk2 is being examined to the hilt. Processes have been gleaned from Chk1 whereby we know that molecule has a side arm that helps with efficacy. John is tweaking the tyk2 according to the journal �cell� to help with the resistance of the molecule. Fortunately we are not dealing with salespeople and their who what when how ******, here we have 2 knowledgable guys with a genuine ambition and an understanding on how to beat something that will kill 1/2 of males. Got to say I envy a few of the posters on here who hold a lot more shares than I do. However, each to their own, my own thinking is no news is good news and I will keep increasing my holding until the tyk2 licence is announced. Love peace and harmony.

The main event will be the tyk2 deal. If Chk1 continues as good as preclinical studies showed in p1&2 it�s an added bonus. With both, a Mcap of �100m is a realistic price and a tradeable one, upon news release of the tyk2 deal. Keep holding on, impatience is a form of anger. There�s nothing to be angry about here, surely, when you look at the likes of ukog declaring 7- something bpd after talk of national interest. It�s mostly slaver to move the herd. Ego, impatience and sarcasm can define the difference between an investor and a gambler. This company appears to be built upon truth and honour. They let the results speak for themselves. Love peace and harmony.

I was sometimes there at Maiden Castle as we knew it then. Keegan used to use the newsagents on Durham road in bowburn, where I�d been one of the three paperboys. Ken and Liz were mad Nufc fans, the Walker family who had it before them were staunch mackems. Ian walker last I heard was chairman of Durham city F.C. I caught my very first fish a rainbow trout at the back end of maiden castle. I got to say, Peter Beardsley was top class, I�d watch him play in the 5 a sides during training and he was genius. Thanks for the memorry lutonews. Come on SAR.

Only my thoughts, Some people on here getting excited about a delayed interim. The real excitement starts when tyk2 licence is announced. Alongside very positive Chk1 news. Tyk2 deal; surely 400m is feasible. If the herd buy in when that�s announced, with previous Chk1 news, then it�s boom time. Love peace and harmony.

Cheers Wayne. Similar to myself, I work in revenue protection at the front line. The majority of the work is dealing with Romanians who bypass Gas or electric meters, and they leave them in a seriously dangerous state. What I find is that foreigners love Britain but hate the British. I voted out also, my daughter attends a school were she is one of four English white children in her class out of thirty. We live in a prt of Birmingham were Muslims have been selectively grooming English white girls for ten years or so, in spite of reports to the police. One girl has recently disappeared from the estate. That�s two now I know of. I voted to leave because I don�t want Britain to become a Muslim State.

When they release the RNS, whatever day of the week that may be, you're going to make big or lose small. Love peace and harmony.