Member Info for inanaco

On Scancells website ... Knowlesi is not mentioned

strange how he knows so much

"" Some of us have flagged the unlikeliness of a BionTech deal previously""

when in reality Scancell has commented that the delay was caused by a regulatory process .....

whats interesting if they did not have anything .... why did they need a regulatory process ?

more proof Vaccine plus PD-1 ....

https://seekingalpha.com/pr/17686671-inovio-demonstrates-80-percent-6-month-progression-free-survival-phase-2-glioblastoma

9 neo antigen trials would suggest personal vaccines ........ different class ..
they will potentially compete with
Moditope TCR ...
which does not need Pd-1 ...

if that map Bermuda, is correct we are sitting on the Gold mine ... "only 15 vaccines" ............ any other combo in trial if approved could also potentially have vaccine's added .
The Key to vaccines ......
"avidity"
ATB ..

I think folks don't quite understand that developing the TCR is a huge technical benefit for building a vaccine and using that vaccine, because its allowing extreme analysis of patients blood and the capabilities of the CD4 ..

i would suggest they will be measuring suppressor cells .. i assume they will establish base lines that need to be breached to allow vaccine dominance

LBC on now ... Trump is doing a phone in ...

Crumbs Scancell combo ...

Combine a patient in the first instance with a vaccine .... what a trial that is ...

Swinson’s eurosceptic side – mysteriously neglected of late – was also on display, as she noted: “For too long, power in the EU has been concentrated among those who are appointed, not elected. The structures of the EU have often proved cumbersome to say the least, at times even making this House look modern and streamlined by comparison.”

its a "headline Grabber" to get the Liberals on the front page ... thats all Crumbs

jo swinson ....
https://brexitcentral.com/the-hypocritical-lib-dems-want-to-ignore-the-result-of-the-brexit-referendum-they-demanded-a-decade-ago/

which is why his speech was amusing ...

In the 1975 European Communities referendum put forward by the Labour Party in the United Kingdom, Corbyn opposed Britain's membership of the EEC.[200] Corbyn also opposed the ratification of the Maastricht Treaty in 1993, saying: "... the whole basis of the Maastricht treaty is the establishment of a European central bank which is staffed by bankers, independent of national Governments and national economic policies, and whose sole policy is the maintenance of price stability[.] That will undermine any social objective that any Labour Government in the United Kingdom—or any other Government—would wish to carry out. ..

crumbs Corbyn ...

https://twitter.com/i/status/1189875416259006465

except he Voted all his political life with the Anti EU wing of the Conservative on leaving Europe ...

check his voting record he voted against The Maastricht Treaty..............

BoJo did not sign the letter .... Parliament did .

Crumbs for Jo Swinson ?

i was on the floor when i read that ..... reason why the SP is subdued .... The Jezza Campaign has started ...
what a disaster if they get elected .. even Bermuda might swear

car crash interview .... https://twitter.com/i/status/1189857638160293888

Just want to refresh memories from earlier RNS regarding enolase .......... and the reason why Efficacy is of such importance to the valuations ...................

""""""The pre-clinical development of Modi-1, the lead candidate from our Moditiope® platform technology is continuing to progress and the peptide components have now been modified to include an additional enolase peptide. This improvement has meant that the product is expected to be effective in up to 95% of patients with triple negative breast and ovarian cancers. """""""

"""effective in up to 95% of patients """

keytruda at best 30%

This patent involved
[A] - KARIN LUNDBERG ET AL, "Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase", ARTHRITIS & RHEUMATISM, WILEY INTERSCIENCE, US, vol. 58, no. 10, doi:10.1002/ART.23936, ISSN 0004-3591, (20081001), pages 3009 - 3019, (20080929), XP002660176 [A] 3,4 * the whole document *

(Karolinska Institutet)

its the enolase patent

The present invention relates to modified citrullinated enolase peptides that can be used as targets for cancer immunotherapy. These peptides can be used as vaccines or as targets for monoclonal antibody (mAb) therapy. Such vaccines or mAbs may be used in the treatment of cancer.