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I guess gold Flipflops cannot be Trumped or even Bidenned?

D'oh! Spelling and understanding long words bothers me.

Good for SNG but...

There is a possible danger of politicisation by the BBC and others.

Sir Paul Maxime Nurse FRS FMedSci HonFREng HonFBA MAE (born 25 January 1949), is an English geneticist, former President of the Royal Society and Chief Executive and Director of the Francis Crick Institute. He was awarded the 2001 Nobel Prize in Physiology or Medicine along with Leland Hartwell and Tim Hunt for their discoveries of protein molecules that control the division of cells in the cell cycle.

Good news .

I assume this is "nCoV: Developing CoV-bnMABs for therapy of highly pathogenic coronaviruses including SARS-CoV-2" on the NIHR "List of Nationally prioritised (COVID-19) studies: approved on 11 March,see NIHR website.

Why the delay? Please avoid conspiracy theories centred on disinfectant!

Sky had a sane Oxford Prof (in their team) making appropriately cautious caveats about safety and efficacy... however it did sound a bit like "it will all be over by Christmas".

Globally how many vaccine trials are there?

SGD27, thanks for interesting Lancet post.

I note“I like the Solidarity trial”, says Zhi Hong, chief executive officer of the biotech Brii BioSciences and former head of infectious disease research and development at GlaxoSmithKline. Although the trial is not double-blinded, that is acceptable in a pandemic, he says. "

Assuming in a few weeks, our trial has shown a generally safe and effective treatment. What next, in a pandemic?

I assume further trials to address further detailed research questions. I hope in parallel some widespread UK use, possibly under Recovery banner , without double blindedness?

I guess our BoD is happy not to have a daily press conference without possible politicisation?

Lp160606,
" the offering.

Is it a life saving treatment required to be administered at the point of which a patient deteriorates, put prior to a ventilator.

Or, a preventative once chest begins to tighten, and offer as a 10 course remedy do keep them out of a hospital bed altogether. "

Thought provoking. I guess possibly both although hopefully not for one patient. Also I guess "10" is an engineering estimate: a good thing. I hope that given the current reality the current trial answers the big questions and leaves the detailed engineering to front line medics. This is of course not ideal.

Maybe a cunning plan for our drug pricing this year, in particular for NHS pricing , might be based on courses of patient treatment whatever the number of "standard " doses, this year?

LiveLongnProsper

Thanks very much for your post and the work you must have put into it.

Doubtless we small Synairgen investors will survive tomorrow without an RNS but the quality of life for us all is important too.

The Health Secretary's comments about Recovery recruitment and the interferon -beta comments on their website surely invite a Synairgen RNS on Monday about our trial recruitment and relationship to Recovery?

francobrett,

Great that initial funding seems sorted.

I am , possibly naively, very optimistic that this will work: I have taken AZN Symbicort for a few years on a halved dosage in recent years. Hence my interest in dosage.

I vaguely recall a "standard" dosage mentioned for earlier clinical trials.

Do you, or anyone else, know if SNG advised "best guesses" / guidance about appropriate dosages for different categories of seriously ill patients be available in 8 weeks and a bit? I guess regulators will be very uneasy but patients may die as discussions about most efficacious policy is discussed.

KRSS

What is your best educated guess of the probability that the proposed transaction will be successfully completed by Christmas?

I assume that Retired Banker will be more pessimistic.

Other views of interest, my guess for this great event, is better than 50%.

Room

The TLW SP is clearly a very stochastic process. Given the current Covid-19 panics maybe some can get very worried about TLW debt and bank credit committees approving the updated RBL amount . Maybe senior bankers are particularly vulnerable to Covid-19 and Man flu??

I just have bought another 40k shares.

Given the 2020 and 2021 hedging and the very low cost of Ghana production c$10 , TLW will clearly survive very adverse scenarios even though current cashflow breakeven is $45: data sources today's RNS and presentation.

Shpunken,

In a scenario ,Russia v Saudi Arabia , oil war will be over by Christmas, given Covid -19 and associated man flu what is your Brent oil price range, (say 90%) forecast for Christmas 2020?

MisterPositive,

Thanks for your informative post: I had already doubled my holding at c16p.

Do you expect details of current oil price hedges and our current estimated costs of production with full year results?

I guess the warm summer weather will come here before a vaccine jab is approved.

I have never been clear WHY the ICHOR device increases the efficacy of SCIB1. Is there a simple explanation of when zapping patients is effective?

I am a small c£5k holding here and am thinking of increasing it: driven partly by relatively huge profits on gold shares AAZ, CEY and POG.

Given the looming ,if not actual , disaster on State aids in the Brexit trade talks. I was a bit, possibly irrationally, concerned about SNECMA and the "wicked" French : I am 65. However should one be more concerned about pure GE competition for Airbus engines?

How important is new Airbus engine business for RR ?

Thanks for any responses.

Rats

I know nothing of Keith Flaherty except through postings here...but isn't Scancell in the business of producing cancer research AND commercial activity? Thus how effective Keytruda + SCIB1 is for late stage melanoma patients may "just" be of adequate medical and scientific interest for an eminent Harvard professor.

"Does anyone seriously believe a man of his standing and dedication to curing cancer would remain committed to the SCIB1 trial out of...."

Maybe some, Bart Simpson like, shareholder should ask him and use the response for Scancell SP ramping??

Indeed Shedulike, maybe all POG LTH still alive will live quite happily ever after.

Shedulike

RetiredBanker says so? Like Lisa Smpson he is usually right about these sort of things! IMHO