Roundtable Discussion; The Future of Mineral Sands. Watch the video here.
TrekMadone
My , age nearly 67 reaction. watching via Sky was genuine sympathy, even for the ever , I feel over, optimistic PM .
Sadly we are back to the excellent Save the NHS and Save Lives mantra.
As you suggest "the bed crisis" looming may be somewhat alleviated with creative uses by clinicians of better treatment options such as SNG. While short of the home trial ideal maybe some effective patient and clinician/ nurse solution could be found for the least ill but hospitalised patients involving SNG or other appropriate treatment.
For the record, I hold 15K shares and made oodles of money from them since they were bought before the unsurprising trial results.
The great and the good should be both at the same time.
Maybe the UK public , inevitably political, debate should be better informed about treatments such as SNG? The arguable overfocus in public debate/ media coverage on lockdowns , case numbers and vaccines which goes back to the early days of the pandemic and the care home tragedies have avoided strategy evolution to include improved treatments in the face of looming severe national economic problems
Does anyone know where the Swedes are today?
"The Q&A did not offer the confidence we expected and although they promised a final investment decision it seemed they required a few things coming together which still may happen but also may not."
As a small (250k shares) investor here for the first time this morning, i thought that in the circumstances the Q&A was appropriate and competent. In particular the tax issues/problems. Q4 targets may or may not be met I have shares in SDX and longstanding but dated LNG interests.
Can anyone make an educated guess, in the absence of a miraculously effective vaccine, about where the UK Government is on the NHS use of treatments, such as SNG001, to mitigate risks and deaths from Covid 19 this winter?....and next?
As a pragmatic , legally naive, European Brit, I cannot help wondering whether this is the sort of very welcome state aid that would break state aid rules if there were to be any: "it has secured funding from Innovate UK, the UK's Innovation Agency, through the 'UK Research and Innovation (UKRI) Ideas to Address COVID-19' funding strand".
CofE,
What is a suitable fate for those responsible for a Pox Hub related leak?
I agree with RetiredBanker about the 5p gamble on POG (and IRC): I still hold 225K which is a large value holding for me.
A key point is that the POX hub has been is and will doubtless continue to be a huge success.
However I feel in need of a Dummy's guide to boardroom politics in Russia. Are the battles largely centred on (control of) the Pox hub? From a PI perspective what are the pros and cons of the two factions?
I guess gold Flipflops cannot be Trumped or even Bidenned?
Good for SNG but...
There is a possible danger of politicisation by the BBC and others.
Sir Paul Maxime Nurse FRS FMedSci HonFREng HonFBA MAE (born 25 January 1949), is an English geneticist, former President of the Royal Society and Chief Executive and Director of the Francis Crick Institute. He was awarded the 2001 Nobel Prize in Physiology or Medicine along with Leland Hartwell and Tim Hunt for their discoveries of protein molecules that control the division of cells in the cell cycle.
Good news .
I assume this is "nCoV: Developing CoV-bnMABs for therapy of highly pathogenic coronaviruses including SARS-CoV-2" on the NIHR "List of Nationally prioritised (COVID-19) studies: approved on 11 March,see NIHR website.
Why the delay? Please avoid conspiracy theories centred on disinfectant!
Sky had a sane Oxford Prof (in their team) making appropriately cautious caveats about safety and efficacy... however it did sound a bit like "it will all be over by Christmas".
Globally how many vaccine trials are there?
SGD27, thanks for interesting Lancet post.
I note“I like the Solidarity trial”, says Zhi Hong, chief executive officer of the biotech Brii BioSciences and former head of infectious disease research and development at GlaxoSmithKline. Although the trial is not double-blinded, that is acceptable in a pandemic, he says. "
Assuming in a few weeks, our trial has shown a generally safe and effective treatment. What next, in a pandemic?
I assume further trials to address further detailed research questions. I hope in parallel some widespread UK use, possibly under Recovery banner , without double blindedness?
I guess our BoD is happy not to have a daily press conference without possible politicisation?
Lp160606,
" the offering.
Is it a life saving treatment required to be administered at the point of which a patient deteriorates, put prior to a ventilator.
Or, a preventative once chest begins to tighten, and offer as a 10 course remedy do keep them out of a hospital bed altogether. "
Thought provoking. I guess possibly both although hopefully not for one patient. Also I guess "10" is an engineering estimate: a good thing. I hope that given the current reality the current trial answers the big questions and leaves the detailed engineering to front line medics. This is of course not ideal.
Maybe a cunning plan for our drug pricing this year, in particular for NHS pricing , might be based on courses of patient treatment whatever the number of "standard " doses, this year?
LiveLongnProsper
Thanks very much for your post and the work you must have put into it.
Doubtless we small Synairgen investors will survive tomorrow without an RNS but the quality of life for us all is important too.
The Health Secretary's comments about Recovery recruitment and the interferon -beta comments on their website surely invite a Synairgen RNS on Monday about our trial recruitment and relationship to Recovery?
francobrett,
Great that initial funding seems sorted.
I am , possibly naively, very optimistic that this will work: I have taken AZN Symbicort for a few years on a halved dosage in recent years. Hence my interest in dosage.
I vaguely recall a "standard" dosage mentioned for earlier clinical trials.
Do you, or anyone else, know if SNG advised "best guesses" / guidance about appropriate dosages for different categories of seriously ill patients be available in 8 weeks and a bit? I guess regulators will be very uneasy but patients may die as discussions about most efficacious policy is discussed.