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What is done is done: there is political risk here.

However POX has indeed transformed the core business with further gains are to come . Maybe this is an appropriate end for IRC guarantees?

Many of us LTH would have lived with giving the IRC stake away in the darkest days.

What does Retired Banker think?

Why? Maybe SNG001 made it to the DC radar??

Prion25 Sunday2215,

D'oh! I think evidence based academic debate on the Peter English view would be very worthwhile.

As an investor here for a year and in Scancell for a decade , I cant help feeling that relatively pure/basic research into the immune system should be well funded by a UK research council.

D'OH ! I have never understood the magnitude of Synairgen's major share price movements and have only read a handful of today's posts but ..... Why for a home trial of patients, not yet requiring any oxygen, is the speed of recovery to say no breathlessness (i.e some quality of life/recovery measure) for placebo and our treatment not reported for the home trialists ?

Really impressive and confidence building interview...

but I was surprised there was no reference at all to the tax position. What is the current position with tax authorities? Apologies if I have missed some news.

D'oh, I have just read this post from the New York Times.

Am I alone, excepting Bart Simpson, in thinking that today's price volatility is due to more than old New York news?

There were media reports from Chinese sources in March of a more transmissable variant of two. I vaguely recall that at the time UK media "experts" dismissing those reportas with variants occur all the time.

Since March I assume the WHO and UK experts and advisory committees have been on the look out for for what has just been reported in London and SE England. I guess some hospitals will now be overwhelmed notwithstanding treatment improvements .

I guess with the new US A president and his team USA triallists will be more supportive of the home use option to keep patients out of hospital.

I am a small (c£3k) holder here.

I assume new information is not available to persuade more bondholders. : who are they ? Aside from a quick resolution of the tax issue, I guess "Kansas City" bondholders from an earlier age have to be offered something, is that likely to be free equity options?

pm jh,

Do you think a junior health minister should be asked about this , next week?

D'oh,

Press report 17/10/20.
"Currently, the drug dexamethasone is still the only therapeutic shown to be effective against the novel coronavirus for severe patients, the chief of the World Health Organization said Friday.

Currently, the drug dexamethasone is still the only therapeutic shown to be effective against the novel coronavirus for severe patients, the chief of the World Health Organization said Friday.

WHO Director-General Tedros Ghebreyesus addressed journalists at a twice-weekly webinar from Geneva on the fight against the pandemic.

He revealed interim results from the WHO's Solidarity Therapeutics Trial "

No discussion of effectiveness measures, dexamethasone side effects or treatment of less severe patients which may also become a major NHS concern.

TrekMadone

My , age nearly 67 reaction. watching via Sky was genuine sympathy, even for the ever , I feel over, optimistic PM .

Sadly we are back to the excellent Save the NHS and Save Lives mantra.

As you suggest "the bed crisis" looming may be somewhat alleviated with creative uses by clinicians of better treatment options such as SNG. While short of the home trial ideal maybe some effective patient and clinician/ nurse solution could be found for the least ill but hospitalised patients involving SNG or other appropriate treatment.

For the record, I hold 15K shares and made oodles of money from them since they were bought before the unsurprising trial results.

Is it practical, in all the current and near term prospective circumstances to plan for interim analysis of available results from a SNG Phase III trial by Christmas or 1 Jan?

The great and the good should be both at the same time.

Maybe the UK public , inevitably political, debate should be better informed about treatments such as SNG? The arguable overfocus in public debate/ media coverage on lockdowns , case numbers and vaccines which goes back to the early days of the pandemic and the care home tragedies have avoided strategy evolution to include improved treatments in the face of looming severe national economic problems

Does anyone know where the Swedes are today?

"The Q&A did not offer the confidence we expected and although they promised a final investment decision it seemed they required a few things coming together which still may happen but also may not."

As a small (250k shares) investor here for the first time this morning, i thought that in the circumstances the Q&A was appropriate and competent. In particular the tax issues/problems. Q4 targets may or may not be met I have shares in SDX and longstanding but dated LNG interests.

Can widely respected humanised mice catch Covid-19?

Can anyone make an educated guess, in the absence of a miraculously effective vaccine, about where the UK Government is on the NHS use of treatments, such as SNG001, to mitigate risks and deaths from Covid 19 this winter?....and next?

As a pragmatic , legally naive, European Brit, I cannot help wondering whether this is the sort of very welcome state aid that would break state aid rules if there were to be any: "it has secured funding from Innovate UK, the UK's Innovation Agency, through the 'UK Research and Innovation (UKRI) Ideas to Address COVID-19' funding strand".

CofE,

What is a suitable fate for those responsible for a Pox Hub related leak?

Synairgen (SNG) SP was up 500% on Monday on news of wonderfully reported 100 patient Phase II trial results: almost flat since. I guess there is almost no SP substitute for demonstrating efficacy .

I agree with RetiredBanker about the 5p gamble on POG (and IRC): I still hold 225K which is a large value holding for me.

A key point is that the POX hub has been is and will doubtless continue to be a huge success.

However I feel in need of a Dummy's guide to boardroom politics in Russia. Are the battles largely centred on (control of) the Pox hub? From a PI perspective what are the pros and cons of the two factions?