Member Info for GlenFidrich

Really not sure what there is to be negative about here. This amended agreement is, as per the RNS, "expected to clear (the) path to advancing clinical development of SRA737", precisely when many were questioning Sierra's motives and the lack of activity with regard to SRA737. Up until now, Sierra have been distinctly lukewarm on developing SRA737, preferring to focus on Momelotinib. Today represents a complete about-turn and sea-change in Sierra's approach which is surely good news. The decrease in the additional milestone payments represents an 11% discount only, and, as TM states, "we are confident that this amendment will expedite the advancement of the SRA737 programme in a timely manner". Sorry, but what's not to like? Or am I barking?

Are we allowed to blame the MMs for the ridiculous spread? 13.64% is really killing the buying.

What's up is the very same herd which managed to propel the SP above 3p have now stampeded out of the building, leaving the LTHs to lick their wounds. But I would guess most of us are still in profit (more or less). What we really need to be asking ourselves is are we investors or traders? If you're the latter, you'll probably do OK out of Sareum (if, that is, you can call the highs and lows - good luck with that). If you're an investor, and can see the true potential (which admittedly may or may not come to fruition), you're in Sareum for the long haul - for the licensing deal, for the buyout, for the life-changing return on your investment. These blips, whilst demoralizing, should not dampen our resolve. There is so much news to look forward to that I really don't think now is the time to throw in the towel, but each to their own, I guess.

The chat forum went down at around the same time as Pfizer's new vaccine announcement (around midday) - why wasn't the announcement made at 7:00am? People have been complaining of being unable to trade on various trading platforms thereafter (e.g. HL). Sareum's rerate in October was, imho, more to do with the patent allowance for SDC-1802 - nothing to do with Covid, in other words. Yet we tank 26%. Also, not sure of the correct volumes, but hardly huge numbers when we remember the number of shares in issue. Something is just not right here, or am I barking?

Ibrox, don't give up your day job.

Warty, profuse apologies if you took umbrage. It's just I thought you had sold out already, because why on earth would you remain invested in a company that was so obviously mismanaged? I did, indeed, question the commitment of some in Sareum, when they were issuing public statements with glaring errors within (must have been my OCD playing havoc again!). But I hung in there, and I'm mighty glad I did! A brief look back at your post history, and nearly every post is negative. For example, from 22/9: "Here we go again- gradual slide downwards until the next bit of "news" then a blip then a slide etc etc.
Now blatantly obvious TM and BoD are absolutely useless at anything but shaking test tubes and taking shareholders' money.
Even the most optimistic posters to this board, if asked to be honest with themselves, would admit that management of this company is absolutely appalling and getting us nowhere. Doubt if we will even be around this time next year on present showing. Jam tomorrow, but as we all know tomorrow never comes". The SP at the time was 0.755. It has subsequently risen to 3.09 (and pulled back, admittedly), yet you're still dissatisfied? And another post from you from 13/7 when the SP was 0.53: "We thought it would be a blood bath last year but they sweet talked their way out of it and we're no further on in terms of the much trumpeted increase in shareholder value, or anything else for that matter. A veil of torpor seems to have settled over Pampisford which seems destined to remain ad infinitum under the present BoD. BoD? Bunch of Dinosaurs". Would you care to retract these posts? But this was my point. Sometimes there's no pleasing people. I like to surround myself with positivity, but you're just unable to acknowledge the positives here, and seem intent to drag everyone down into your negativity. Best sell up, Warty, and find greener pastures, surely?

That wasn't me, I promise!

Hey Aber, thanks for your condescension ("don't quite think you get it"). On the contrary, I think it's you who doesn't quite get it. "They've had 15+ years to work out how to manage a company", blah, blah, blah. Do you think that drug discovery happens overnight? This from Sareum's website: "Sareum discovers and develops innovative drug candidates aimed at cancers and autoimmune diseases. Our drug development programmes aim to improve outcomes for patients with serious medical conditions and where current therapies are inadequate." So you think this can be achieved at the drop of a hat?!!! Grow up, and grow a pair! Our patience will be rewarded, but you know, of course, what to do if you're unhappy with progress... Moron!!

Holy crap, Hog Wart! Just over a month ago the SP was in the 0.70s. Today it's up over 160% and you're still complaining!! Give it a rest, for the love of God. Let the BoD get on with whatever it is they do (which, given the SP increase, can't be all bad), stop your sniping from the sidelines, and just chill!! One thing I've learned from my 50+ years is that you can't please everyone all of the time. But for Hog Wart, nobody can please him, any of the time! Jeez, I'm about ready to explode with this nonsense - my OCD is off the scale at the moment, so please just STOP!!!

Bridges, well spotted, but the article makes mention of ProNAi Therapeutics which is the old name of our friend Sierra Oncology (changed in January 2017 I believe), so not sure how up-to-date it is. Anyone?

OK, 40m shares, but still only a little over 1% of the shares in issue. I might be concerned if the SP fell 10% on 400m shares traded, but my point is large % falls on thinnish volume somehow just doesn't add up, but it might just be me.

Without news, the SP will continue to drift I guess, so not a bad strategy Utah. I always go back to volume on drops like yesterday. 20 million shares traded and we're down 10%? Seriously? Also, try doing dummy sells on days like yesterday. One would think it would be NT to sell if everyone is running for the exit. But, oh no, I can sell no problem (slightly above the bid) which suggests accumulation on the cheap by whomever (also, look at the spreads). I think we've all seen this sort of drop before on many occasions, and it often presages a significant move up imo. We shall see. Good luck one and all.

Many of us will still be in profit at 1p, so f u. Enough said on that particular thread.

Ben, I remember buying into BP in the early 1990s ('91 or possibly '92) at a price of 223p. I sold out a year or so later at 323p, making exactly 1 pound a share (I had bought 3,000 shares - I was young and thought I was the next WB!). The reason I mention this is that (despite what has happened since) we appear to be near a 30 year low. This is screaming "buy me!!", even if only for the dividend (forget the capital gain). My entry point will be 1.80p (should it happen). But that will be the absolute bottom, surely??

The grant announced yesterday was for a very specific amount (174,000 pounds) which suggests to me that Tim and John had costed their time and research required to explore the potential efficacy of SDC-1801 very precisely, and, what's more, very fairly. In other words, I think they didn't want to exploit the current situation by inflating their costs or asking for more than is needed, which I think further underlines the decency of these two men in whom we have so much invested. Remember, Covid-19 is something of a sideshow where Sareum is concerned (albeit, a pressing one), there being so much news in the pipeline on other fronts. Time to chill, and keep the faith.

Well, today has been interesting, to say the least. It was definitely a case of "buy the rumour, sell the news". But was the news so very bad? From the RNS: "Sareum Holdings plc (AIM: SAR)... is pleased to announce that its application for approximately £174,000 grant award (the "Grant") by UK Research & Innovation ("UKRI") to investigate the therapeutic potential of SDC-1801, its selective, small molecule TYK2/JAK1 kinase inhibitor, in severe phase Covid-19, has been conditionally approved." Great, I hear you say! The only problem was that word around the campfire was that the grant would be in the zillions! The fact is Sareum (perhaps in its usual understated way, or perhaps because there is a reason for the specific amount, who knows) only applied for that which it has been conditionally awarded. Yet the herd/day traders/MMs decided this was awful news and the price dropped 45%? What if Sareum already have a partner to further their investigations? What if further funding is forthcoming? What if news drops re: SRA737, SDC1801/1802, Aurora Flt+3? Like many others who have held for years, nothing concerns me about today's price action - we've seen it all before, and have become maybe somewhat de-sensitized to all the fun and games! I'm still bullish and holding firm. What about you?

2 squids?? In the next couple of weeks?? Whilst I wouldn't complain(!), the ramping crew have most certainly arrived!

So, there are a few posters telling people how foolish it would be to sell your shares now. I don't necessarily disagree, BUT. I was in OXS (Oxus Gold) a while back. I was up 160%, sitting pretty. But I was waiting for the big RNS (supposedly, according to the more well-informed posters, a slam dunk that they (Oxus) had won their arbitration case vs Uzbekistan) and so, naturally, I held out for the decision. The decision (which was announced on Christmas Eve, if I remember correctly) went against Oxus, and I ended up losing everything. All I am saying is, if you're in profit, there is NOTHING wrong with banking that profit. Despite everything, I choose to hang on in there, but please don't berate those who sell in the black. Good for them and good luck everyone else left in the game.

That was Thoth2's calculation of potential value of SAR's molecules to an interested buyer, I believe, although RMM has highlighted other deals that would suggest a much higher figure, and all this before Covid-19 reared its head.

Jeez, we're on the brink here and people are talking about "chancers" and "ne'erdowells" being in charge! I've certainly had my issues with regards to poor communications (particularly in the realm of simple proof-reading errors, which tend to send my OCD into a frenzy!), but to suggest that TM and JR are somehow disingenuous is ridiculous. They're science geeks, first and foremost. I actually suspect that money is the last thing that motivates them. It's the holy grail of finding a cure for cancer that they obsess over, and thus communicating with mere mortals such as us is a tad tiresome. All I'm saying, my fellow Sareumites, is have patience, keep the faith, and allow the geeks to do their thing (in their own time)! Rant over, and out.