RE: Welcome tweet from Lancet Respiratory Med4 Feb 2021 18:18
Again entirely thanks to Matterhorn, this is the conclusion :-
“In conclusion, SNG001, a treatment already studied and shown to be well tolerated in patients with asthma and COPD, seems to also be well tolerated in patients admitted to hospital with COVID-19, with a range of clinical outcomes displaying a beneficial pattern of response to SNG001 therapy. These encouraging data provide a strong rationale for larger, international studies in the context of the ongoing clinical burden of COVID-19. In addition to a phase 3 trial of SNG001 in patients admitted to hospital with COVID-19 requiring no more than supplementary oxygen, it might be appropriate to also assess the safety and efficacy of SNG001 in ventilated, critically ill patients with COVID-19 who have evidence of active viral infection in the lungs. In view of the broad antiviral effects of interferon-ß, the results of this pilot trial suggest that the efficacy of SNG001 should also be assessed in the hospital setting against other seasonal respiratory viruses, which cause considerable morbidity and mortality every year, including cases of SARS-CoV-2 co-infection, which could overwhelm health-care systems during the coming months in the northern hemisphere.“