Member Info for EmeraldCarrots

The MT-RNR1 is not used in loads more neonatal wards all over the World already. One would have thought most parents on Earth would want their baby tested using the MT-RNR1 to make sure the baby does not have a bad reaction to aminoglycoside antibiotics and possibly end up DEAF!! I find it quite ridiculous these machines are not already widely used.......... in the World. It has GOT TO HAPPEN!

All IMHO.

Key Aspects of Aminoglycosides:

Mechanism of Action: They bind to the 30S subunit of bacterial ribosomes, leading to misreading of mRNA and premature termination of protein synthesis.

Spectrum: Highly active against aerobic Gram-negative bacilli, such as Pseudomonas aeruginosa, and some Gram-positive bacteria, like

Staphylococci

Administration: Typically given intravenously or intramuscularly (drip or injection) due to poor absorption in the gut.

Key Examples: Gentamicin (commonly used), Tobramycin (often used in bronchiectasis), Amikacin, Streptomycin, and Neomycin.

Toxicity/Monitoring: Because they can cause permanent hearing loss or renal failure, patients are closely monitored with blood tests to ensure therapeutic levels are achieved without exceeding safe limits.

Precautions and Side Effects:

Ototoxicity: ****Can damage the eighth cranial nerve, leading to dizziness, vertigo, ringing in the ears (tinnitus), or hearing loss.****.

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Erm.......... this is NOT just babies. Using these Aminoglycoside antibiotics can lead to ****ringing in the ears (tinnitus), or hearing loss.****. So at the moment in UK hospitals, and indeed the World? this is a risk worth taking I presume??? Personally I think I would want the £100 test to avoid thius possible outcome!!!!!!!!!!!!!!!!

Is deemed a must have what part of the government can compel hospitals to use it?

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In the USA, there is no single entity that can directly force a private hospital to purchase a specific new medical device simply because it is deemed a "must-have." However, federal agencies can effectively compel adoption through regulatory requirements, standard-of-care definitions, and reimbursement mechanisms.

The primary parts of the government involved are:

1. The Centers for Medicare & Medicaid Services (CMS) - Economic Compulsion

CMS, under the Department of Health and Human Services (HHS), holds the most direct power to compel adoption.

Coverage and Reimbursement: If CMS decides a device is "reasonable and necessary" and provides high reimbursement (or creates a new billing code), hospitals are financially incentivized—or often forced—to adopt it to remain profitable and competitive.

Conditions of Participation (CoP): CMS can mandate that to receive Medicare/Medicaid funding, hospitals must follow certain protocols that may effectively require the use of a specific technology, such as updated electronic health record systems or approved diagnostic equipment.

2. The Food and Drug Administration (FDA) - Regulatory Authorization

The FDA regulates the safety and efficacy of medical devices, which is the first step toward a "must-have" status.

"De Novo" or PMA Approval: For novel, high-risk devices, the FDA’s Pre-Market Approval (PMA) process ensures the device is safe and effective.

Emergency Use Authorization (EUA): During a public health emergency, the FDA can issue an EUA, allowing for the rapid deployment of a device. While technically voluntary, the urgency makes it a "must-have" in practice.

Especially the MT-RNR1 one, which on approval should be the only portable fast device in the USA to test babies to see if they are vulnarable to aminoglycoside induced hearing loss (AIHL) due to the use of aminoglycoside antibiotics. Will ALL the neonatal wards in the USA need these machines?

They strengthen the sales side. To date I for one am not too impressed with the sales of either machine to date. They seem to be excellent machines that should be in great demand anywhere in the world............. As I have posted before I believe we need to find a sales Director experienced in selling medical machines to Countries in the EU. Ideally that person should be fluent in at least one other European language other than English. The title could be "European Union sales director" for example. Also later this year, when the FDA applications have been submitted we could do with similar for the USA although one language, English would suffice! I'm sure an experienced sales Director will see the enormous potential the Genedrive machines have.

https://genedrive.com/

All IMHO.

So about 2 weeks until the new one.

Correction.

Robert English 14.46%:-

https://www.lse.co.uk/rns/GDR/holdings-in-company-7o2yto326cac7lx.html

David Nugent 24.65%:-

https://www.lse.co.uk/rns/GDR/holdings-in-company-9b3ip2j7ahrvtz9.html

David Medlock 3.33%:-

https://www.lse.co.uk/rns/GDR/holdings-in-company-hxnfeox6wrw0ccm.html

==========

Total:- 42.44%.

Do we know anything more about this Man?

More please!.

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The Red Sea. If it's a matter of money maybe the rest of the World should chip in. Why this was not done decades ago is a mystery.

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Even if it cheaper or easier by tanker more pipelines could be available if needed. Why has this not happened decades ago??????????????? Maybe Trump should talk to the Saudis and get them working on this!!

The Red Sea. If it's a matter of money maybe the rest of the World should chip in. Why this was not done decades ago is a mystery.

The RNS called "Genedrive PLC Scotland NHS “test of change” pilot programme" dates 18/12/2025 @ 7:00am.

One would hope that there has been a lot of progress over that near 3 month time period!

https://www.lse.co.uk/rns/GDR/scotland-nhs-8220test-of-change8221-pilot-programme-tvkxvazb4r79kyf.html

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Good.

But what about the Iranian economy? Country now must be sealed off and decending into chaos.

IMHO.

Built pipelines to negate this bottle neck problem that has been a major issue for decades. Why has this problem NOT been negated decades ago? What a joke.

During the placing etc. Waiting..........

Voting rights. See yesterdays RNS.

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