Member Info for EmeraldCarrots

Over time. Sounds to me like clearing it will take months. In the mean time new pipelines and railways can be built to the sea off Oman.

AI Overview

Yes, the Parsortix system is used in the Immatics ACTengine IMA203 cancer drug trials.

According to information from London South East and related investor updates (Cellbxhealth), the Parsortix machine is used in 3 of Immatics' cancer drug trials, including the Phase 3 SUPRAME trial for the IMA203 anzu-cel therapy.

Details on the use of Parsortix in IMA203 trials:

Purpose: The system is used to capture and harvest viable, intact circulating tumor cells (CTCs) from the patient's blood (liquid biopsy).

Analysis: The harvested cells are likely used to evaluate the expression of the PRAME protein on the CTCs to determine patient eligibility for the T-cell therapy.

Application: It is used to support the development of Immatics' PRAME-directed, autologous T-cell therapies (ACTengine) for solid cancers, including melanoma.

The Parsortix system, developed by ANGLE PLC, is FDA-cleared and used to collect circulating tumor cells (CTCs) for analysis, which helps in identifying cancer targets and monitoring treatments.

Https://clinicaltrials.gov/search?term=ima203&viewType=Card

Newbieinvest.

Needs a huge turnaround this year in terms of doors being opened.

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As I have posted many times they seem to have two fantastic machines that would save any hospitals a load of money. One of the machines can help prevent babies in neonatal wards being rendered deaf by a bad reaction to the commonly used (and cheap) antibiotics. You would have thought a sales persons dream come true.

The other machine can check someone will respond in the expected way to the most commony used drug given after you have a stroke. Some people's genetics means they won't react to this drug that helps stop them haveing another stroke withinn 2 weeks (which is quite common).

So one machine helps prevent babies being made deaf and the other weed out the people who wont respond to the usually used stroke drug.

How on Earth can a sales team not make good progress with these???

Https://rotunda.ie/eistigi/

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This should be happening at the most major neonatal hospitals ALL OVER THE WORLD.

Now we are better financed this should take off. What parent would allow their baby to possibly be rendered deaf by the very antibiotics used for treatment when Gendrive's test could be done in less than half an hour, costing what...... £100 to hepl make sure the baby wont have a bad reaction and go deaf???? Other major neonatal hospitals ALL OVER THE WORLD need to start doing this test. It's firking obvious.

Https://rotunda.ie/eistigi/

Also sales staff that person will manage. From where I'm sitting it would be a fantastic opportunity for someone to make a huge impact and frankly get rich if they negotiate a decent bonus from sales. A truly fantastic opportunity for someone.

Also sales staff that person will manage. From where I'm sitting it would be a fantastic oppertunity for someone to make a huge impact and frankly get rich if they negotiate a decent bonus from sales. A truly fantastic oppertunity for someone.

Now GDR is more properly funded, with two World class machines, one hopes a strengthened sales team will now deliver the goods. Grom todays RNS:-

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People

The Board would like to recognise and thank our highly skilled and dedicated team, whose commitment and resilience have been instrumental in progressing the Company's strategy during a challenging period.

The Company's commercial team reduced from 11 to 4 people, primarily driven by funding constraints, which impacted staff retention and limited recruitment activity. While this has created short-term capacity challenges, the Company has remained focused on prioritising core activities and maintaining operational effectiveness.

The Board intends to rebuild capability in line with the Company's financial position and strategic priorities following the successful post-period fundraise.

Following the recent fundraise, Tom Lindsay has retired as Non-Executive Director, and we would like to express our sincere thanks for his valuable contribution and service to the Company.

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One assumes they will be recruiting fresh sales team people, right away.

All IMHO.

Stocksaint

The sales team have had more than enough time to get the Government health services in all the EU Countries at least evaluationg the MT-RNR1 by now. As we know this is the machine that is used to check, via just a cheek swab, if a new born baby might have a bad reaction to the usually used antibiotic and be rendered deaf! So the baby could be deaf and what cost to any countries health service from then until the person dies of old age? £ millions. I say YET AGAIN this is a sales persons dream come true. It seems obvious to me that the sales side at Genedrive has major issues that urgently need sorting out. I pray the half year report, due now, proves me wrong and sales have rocketed.

All IMHO.

Sales in the Half Year report Gino Miele and Russ Shaw need to do something to get things moving more on the sales side. Weeks, months and years go by and frankly progress is painfully slow. As far as I am concerned it is not good enough. How on Earth can you have the two fantastic macnines available, yet overall sales thus far are pathetic, campared to the market available. The MT-RNR1 has been conmmercially available for over 2 years. TWO YEARS!!! Frankly what do the sales side do all day? This is a machine that should "sell itself". Unless sales have more than doubled it is simply not good enough.

All IMHO.

ButterMyCrumpets.

"Nope, not expecting anything to be fair".

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I'm expecting:-

1. Increased uptake of both machines.

2. More contries in the EU evaluating the machines for possible Country wide implementation.

3. Mone Countires in the middle East ditto.

4. News on the FDA applications in the USA.

5. Strengthened sales team.

Fb2020.

From final results RNS dated 5th December 2025:-

Building on FY25 total income of c.£1m, the Group has visibility currently for around £0.9m of total income already in FY26, which is based around:

§ NICE Early Value Assessment (EVA) evidence generation completion and submission, which is expected to be a catalyst for wider UK implementation.

§ Scotland's phased national implementation of the Genedrive® MT-RNR1 ID Kit and the CYP2C19 point of care pilot (an assessment against laboratory testing pathways) both commenced in October 2025.

§ The Manchester University NHS Foundation Trust commencement of the 12-month Acute Coronary Syndrome and CYP2C19 rapid genotyping programme.

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One hopes we have even more more visibility now!

Would love to see someone overseeing sales to the EU. Someone with sales experience sellling medical machines in the EU, who proferably speaks two or 3 languages. Also someone for the Middle East (assuming it still exists!). Later this year someone based in the USA overseeing USA sales.

All IMHO.

LOL! Maybe so you had less time to sell after the shock!

27/03/2025 15:29 RNS Regulatory News Genedrive PLC Half-year Report

MM's showing big trades from 08:40 ish AM showing up now. And the bid is still 2.5p....... 4m seeminly bought at 2.7p ish. Oh dear.

Hold on to your hats?

SemaphorRed.

I'm not sure if you know what "pump and dump" means (where's the pump?) nor why a market maker would be wary of it, nor why if they were wary of it they'd provide a larger spread with many small trades.

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Pump = lots of regular very small buys (loads here are less than £100 per trade). Other see loads of buys and join in. Then the buyer gets to a certain level and dumps the lot (a few million shares........). This is my understanding of this.

IMHO...........

Clowns! Where is the half year report??