A.I. Are ctc's caught by parsortix ideal for analysis?12 Jun 2025 15:39
"AI Overview
Yes, circulating tumor cells (CTCs) captured by the Parsortix system are considered well-suited for analysis. The Parsortix system is known for its ability to isolate and harvest CTCs with preserved morphology and high purity, making them ideal for downstream analyses like DNA, RNA, and protein analysis, and even for culturing.
Here's why Parsortix-captured CTCs are valuable for analysis:
High purity:
CTCs harvested by Parsortix are of higher purity compared to other methods, meaning fewer blood cells are present in the sample, leading to cleaner analysis.
Preserved morphology:
A significant advantage of Parsortix is that it preserves the morphology of the captured CTCs, allowing for visual inspection and analysis.
Antibody-independent:
Parsortix does not rely on antibodies for capture, allowing for the detection of all sub-populations of CTCs, including those that may not express standard epithelial markers, like EpCAM.
Downstream analysis capabilities:
The Parsortix system allows for the isolation of live, viable CTCs, enabling a wide range of downstream analyses, including culturing and molecular profiling.
Ease of use:
The Parsortix system is relatively easy to use, making it a viable option for routine cytopathology laboratories.
Superior harvest rates:
Studies have shown that Parsortix harvests CTCs in a greater proportion of patients compared to other methods, including antibody-based systems.
Ideal for clinical trials:
The Parsortix system's ability to harvest and analyze CTCs makes it well-suited for use in clinical trials and clinical management, according to one article. "
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