Member Info for crumbs

:) Hopefully a whole convoy of buses ... but yeah whatever is coming we are now a week closer to it .... if it doesn't come I expect sp to drift down some more but if it does come it'll be 10p and beyond

What I do not get is if you were a holder why would you have any kind of problem with the arrival of the Diggles and their Vulpes fund? Just don't get it... we went from 4p to over 9p great for traders and beyond that we have serious investors on board with their skin very much in the game and seemingly willing to put more in ... plus many say the science is beyond them including the Diggles but they sent in an expert to go through the science to visit the labs and out of over 20 potential investments they were seriously looking at they chose scancell.... its all very much like turning the positive of being in last 10 of grand challenge into a negative... just how? why?....

Not sure why you think that?.... however it is indeed possible Vulpes will take their holding up to 25% at some point if needed and the sp could be anything and of course there could be others wanting in or to increase their holdings plus it really could be an OO next time too... but that next time will not be coming this year I think you can agree on that...

Vulpes typically take a 15-25% stake in the companies they invest in... they have 16% now in scancell I do not think the price is as much an issue for them as the % pf holding... and obviously, they could take that 16% up to 25% if needed .

The smarty ladder sounds like fun.... Scancell have CALC HYG and OXT all longterm ii investors as you will know I do not see that Vulpes will be any different apart from they will possibly take a more proactive role and indeed support scancell through its future progress if that means further funds... They like many of us LTH understand the potential of scancell... if you saw my earlier post, Lindy's science cured a young 9-year-old girl back in the 1990's who now has a 9-year-old daughter of her own... Our SCIB1 mono swimmer chart talks for itself... and moditope well Lindy has seen nothing like it... but it needs to go into trial and we are now all set up for that ... exciting times ahead I think and it is up to each individual if they want to be a shareholder for it :)

Bit dramatic... lol

Vulpes have their own paid scientific advisor who spent a long time researching the science of scancell including visits to the Notts labs and meeting Lindy and team scancell science... obviously they will be wanting the timelines to flow just as much as all investors do but It sounds like they have invested for all the right reasons and that is because they have faith in the science... this is not VAL or SAR

Yes it takes some of the fear factor out of this risky investment which I think is why the sp did not sink to 5p and below on the announcement of the Diggles buying in but indeed went on up to challenge 10p and I reckon on more positive newsflow it would have broken 10p and probably still will... when it comes! lol ... we have gone back to frustration over timelines again... but for me, it means I'm back to nibbling :)

Off the top of my head, Moderna are into mRNA much like BioNtech and have as BioNtech managed somehow to raise huge amounts of money again off top of my head -over $2 billion to fund... well not much in way of clinical results....

Nice little anecdote there about Lindy's early success ... very happy to know those two have gone on to have full lives.. why has no one pushed Lindys work into more clinical trials I do not know!!!

Treated at 9 and now has a nine year old :)

https://www.dailymail.co.uk/health/article-1278836/Holy-Grail-cancer-vaccine-blasts-tumours-weeks-hailed-huge-leap-fighting-disease.html

And the last bit :)

'During the question time, it emerged that
the own research results that surprised her most over the years are that they
The CD4-positive cells are so potent (see
vimentin studies above). In conclusion, Durrant looks brightly at immunotherapy
future development. She estimates that
even the cancers that today are classified as
immunologically "cold" successfully
will be able to be treated with immunotherapy.'

'
Durrant began his lecture on that
present the researcher behind his honorary lecture, Jan Waldenström. He is
best known for being 1944
first to describe and thus be able to name the disease Waldenström's macroglobulinemia.
She went on to tell
a couple of patients with advanced osteosarcoma who have been cured of treatment
with the anti-idiotic antibody of
the glycoprotein CD55. One of them was nine
years when she was treated and now has herself
one 9-year-old daughter, while the other, who
was also treated at a young age, nowadays is
oncologist.'

Google translate knows Swedish :)

'This year's lecture to Jan Waldenström's memory was held by Lindy Durrant,
professor of cancer immunotherapy at
University of Nottingham. She is a pre-clinician, but she runs many
years of translational research and combines preclinical and clinical studies
with potential cancer vaccines and
antibodies in various cancers. She
is a pioneer in the research field by using anti-idiot type
antibodies such as cancer vaccines. On
The track record also states that she has developed
a unique strategy to generate monoclonal antibodies against glycolipids,
at the same time as her research group developed a DNA vaccine platform
which stimulates T cells to effectively kill cancer cells. Beyond that, she is
founder and chief strategist for the company Scancell.'

page 32 :

http://onkologi.org/wp-content/uploads/2019/05/cancerlakaren_2_2019_ua.pdf

So it is possible the first patient/s have been dosed ... though we should this being scancell err on the side of timeline caution lol ... knowlesi is right it will not be logistically simple to get running ... again the Ichor element I reckon will be the biggest issue... new devices to be shipped over and put into participating clinics and staff trained to use them... They will also have had to dig the long since mande SCIB1 out of the fridge from behind the Philadelphia and run tests on it to see if it is still stable and useable and then on into the clinics that the Ichors will be at... still that is what they are all paid for :) .. I really hope the modi1 trial is already in advanced planning stages seeing as the one timeline there of tox testing comes to end by end of this year... we all know that these delays are what have brought the sp upwards momentum to a stuttering retreat from bridging 10p and know that longer it goes on more likely it is the Diggles will be tapped up again with no clinical data attached.

I think there are a few... but probably all covering same trials... I'm sure original trial was on that site though

Yeah, they will be on to it like a flash... once it shows up lol

Well, that is why I put a '?' because I'm not 100% sure I know the last trial was and I presume it is the protocol .... So I was expecting to see it come up as a recruiting or about to recruit trial and get to see what clinics etc.. but nothing so far which considering it was to start as of now I find strange... Still, like yourself hopeful next week we get something :)

There is no SCIB1 pembro combo showing on clinical trials registry yet though... I'd have thought it would?

It could be SCIB 1 has been in the fridge so long no one can now find it....we l can sympathize with that one