Roundtable Discussion; The Future of Mineral Sands. Watch the video here.
The SCIB1 + CPi data that is about to be shared is very important in the journey towards the proposed Registration Trial. The last update was for 13 patients that had all reach the minimum of a 1st scan. The response rate was 11 out of 13. In the months that have past since then we could see that number close to 20 patients and the minimum target for a response is 14 ( 70% ).
The ORR is extremely important and anything 80% or above will be fantastic.
Additional to the late April Conference.
Immuno-Oncology Summit Europe 23rd & 24th April 2024.
Day 1 @ 14.45 Lindy Durrant
'Clinical Update on the DC Targeting Melanoma Vaccine, SCIB1 and Modi1 Vaccine Targeting Citrullination'
My presumption is that this will contain some new data, it doesn't say that it definitely will but 'Clinical Update' is a perfectly good clue for me.
@Green453
This weekends presentation is all about SCIB1 + CPi's, there is another conference at the end of April ( Immuno-Oncology Summit Europe ) where Scancell are to present updates on both the SCOPE Trial and the ModiFY Trial.
So if there is no mention of MODI1 on Sunday we will have to wait until the 23rd.
Unless there is an RNS update earlier.
And on the Friday 5th we will find out about our Late Breaking Abstract.
ABSTRACTS
The titles and text of all regular abstracts (submitted for the November 16, 2023 deadline) and the titles of the late-breaking and clinical trial abstracts (submitted for the January 8, 2024 deadline) are now available on the online itinerary planner.
âĄď¸The text of the late-breaking and clinical trial abstracts will be posted to the planner on Friday, April 5.âĄď¸
It does feel like there a lot of threads being pulled together. Year End in six weeks and that does focus managements attention towards what successes can be included in the year end report.
Can they get a deal over the line and bring in some cash, it always helps to have a big headline in the run up.
Anyway with the Easter break there are only four more trading days prior to the talk by LD in San Diego.
Todayâs announcement is the combination of years of research, testing AvidiMab in the Covidity Trial, the successful trial results from the SCOPE Trial and getting iSCIB+ approved for human testing.
Itâs just one RNS but if itâs just as good as SCIB1 itâs a huge step forward for many more cancer patients facing very serious illness.
The important thing is that iSCIB+ is now a real drug and fingers crossed it will prove to be another Brick in the Scancell wall of cancer treatments.
Correct, there are no promises other than achieving full recruitment in the SCIB1 Cohort.
My list is to point out how many irons are in the fire. Every item listed is capable of landing at any time.
Scancellâs Full Year is the end of April, you would expect that they will be working towards bringing at least one piece of major news into this years accounts.
Will we see any news prior to the anticipated pre-AACR Presentation on the 7th April ?
Here are some candidates that could materialise before the end of next week.
Obviously number one, GenMab to go ahead with a Phase 1 with our GlyMab Target.
GenMab agree a new deal for another GlyMab.
MHRA approve a move to allow Modi1 plus CPI to treat First Line Patients with Renal Cancer.
MHRA approve the addition of cancer target to the ModiFY Trial where the standard of care is a Duplet of Checkpoints.
The six month Evaluation as announced by RNS in July 2024 ( 8 months ago ), should be completed and close to a decision.
Remote but possible interest / deal for AbidiMab or the same for GlyMab.
All of the above could land just prior to Scancellâs Year End.
Iâm interested to know if there are any other left field possibilities.
Violindog
if the presentation is preceeded by an RNS Update on the 5th April I would expect many of us will be getting some shares tucked away in our 2024 ISA's accounts the following week.
The SP at 10.5p is undervalued so anything that suggest Scancell is moving closer to that Registration Trial meaning they can achieve a commercialised Immunobody drug in the future, will send the SP higher. The more real that possibility becomes the greater the probability of major pharma wanting to own it outright.
AvidiMab is as yet 'unproven'. We wait for the first validation from a third party.
We are waiting on GenMab.
We are waiting for iSCIB+
We are waiting for the ModiFY trial update.
We are waiting for another deal for GlyMAbs
And finally we are waiting for Lindy's presentation in two weeks time.
Such a lot to land in 2024.
@magnetmagnetism
Itâs not the shareprice itâs the Market Capitalisation which currently stands at ÂŁ95 million.
Scancell has been much higher in value but those peaks were not sustainable without major news underpinning the larger MarketCap.
What we do know is that our CEO is about to do a 10 minute presentation at the AACR Conference in San Diego on the 7th April.
Both the AACR heading for that presentation and the Scancell heading do suggest that we are about to receive a more up to date report on the SCOPE Trial.
Things like how many patients have now been enrolled, how many have had their initial âneedle freeâ injections, how many have reached 1st Scan and most importantly what the ORR currently stands at. Anything above 70% is on target, the excitement will be if it is still over 80%.
Due to how jittery the markets are I would think that there are many people watching Scancell and waiting for some solid news.
If that does happen early April the SP will respond.
Many of these deals arrive when there has already been a joint programme running.
This deal is a result of those two companies working closely together and Astra has fully appreciated what Fusion Pharma have created and the depth of the pipeline.
Once the SCOPE trial has reached the data threshold to begin the Registration Trial we should see a Partner emerge and that could lead to this kind of deal in 18 months to two years from now.
For balance that is just Immunobody we have three other Platforms.
Ray
AvidiMab bolted on to Checkpoints that would be a ÂŁ1 a share on its own.
If any of us is feeling down we should just contemplate that concept becoming reality. If that doesnât lift your spirits nothing would.
This has been said before, â we are on the cusp of Scancellâs first domino dropping and there could be many to follow â.