Wow4 Jul 2019 16:10
As previously reported, Faron has also received a tumour imaging report of a patient with colorectal cancer, which indicates significant shrinkage of lung metastasis (classified as a partial response according to the RECIST classification). Positively, the patient has also shown a decrease in the tumour load marker CEA (carcinoembryonic antigen), which has normalized along with treatment. In addition, the patient shows an increase in circulating B-cells, which could indicate an antibody-mediated response against the tumour. This patient, whose tumour has been classified as microsatellite instability (MSI)-low, had previously been treated with six different anti-cancer drugs, which had all failed. MSI-low colorectal patients represent around 90% of all colorectal cancers and over one million annual cases globally.