Member Info for CauldStream7

Jonah58

Of all the posts today yours is the most interesting. Thank you for the insight into the possible efficacy of BioAMB and its market potential.
At last we have a transparent picture of what is involved in preparing for the PK Study and what looks like a definite timeline for it. We have been spared the vague and misleading pronouncements of Tim McC who did not let on that the commencement of the Study could take 4 months. Maybe the Board has insisted in much fuller disclosure of what is going on not just with Lupuzor but also with the other products in the pipeline.
The prospects are looking much better for IMM and its shareholders.
I pity poor Lambo who has now returned to his gloom-filled warnings of the CLN repayment - how many times can he repeat himself? I hope he sells his IMM shares and transfers his attention elsewhere.

Nolupus:

Tim has been telling us that Sol, the cancer preventant sun cream, has been making good progress more than once over a period of several months. If this is good progress means I hate to think what poor progress would mean.
The mystery suitors who might bring this to market and pay Incanthera big bucks are unknown to us. I would be surprised if one of them is Avion. More likely they are already big players in the sun cream market.

Pokerchips:

Thanks for your interesting post on Tim McC.
Have you considered that he may have become a mere figurehead? Maybe Avion is not keeping him up to date on the PK Study. Perhaps they have told him that it is a waste of his and their time for him to visit the US. Perhaps some of their directors plan instead to visit the Ureka labs in Bordeaux to see for themselves what they are doing there and if it might prove interesting for Avion to take a financial interest . Perhaps they would like to speak to a real scientist like Prof Sylviane Muller who is said to be working on a Phase 2/3 trial of P140 for treating CIDP which could fit the Avion product portfolio.
I think you should ask Lisa for information of what is really going on. Perhaps she can give you a few pointers.
Finally, I definitely agree with you that in this new transparency age of IMM we are due an update. The lack of one is a cause of considerable concern in the light of the assurances that Tim gave in his Proactive interview in early October. It would convey more credibility if it came from Tim Franklin rather that Tim McC.

MysticMike
I don't think this delay has anything to do with Tim and whether he cares about his shareholders.
More likely it is to do with Avion's strategy for handling the Phase 3 Lupuzor trial which they want to discuss in Europe with IMM's leading scientists like Prof. Sylviane Muller. They may also wish to discuss other products in the IMM/Ureka pipeline such as the use of peptide140 (known as Lupuzor for the treatment of Lupus) for various diseases of the immune system such as CIDP.
We are likely to hear the results of this meeting, I guess, before the end of this year. We have no way of telling whether good news or bad will come from this meeting. I incline to be optimistic because I find it hard to believe that Avion's bosses will come to Europe solely to kick Tim and Co in the pants. They could do so much more cheaply by Zoom or email.

Mystic Mike:

History seldom repeats itself. I hold no great hopes for a positive RNS from IMM before the end of this month but I do have hopes that we shall hear something before Christmas. Surely there will be news of the PK trial and about Ureka research activities by then. Is that too much to hope for?

Lambo222.

You are a manic-depressive. On Tuesday you were talking about an "epic" rise to 170p after a couple of substantial buys.
Now you seem to be on the 5p track. Nuts!
No doubt the actuality will be somewhere in the middle after we get an update on the Avion/IMM front. If it's good we can maybe look forward to the price edging upwards but the degree of the increase will depend on the detail of the RNS.

Some meaningful large buys today.
Perhaps someone has heard that Avion are sending a team to Europe to meet the IMM team within a few weeks instead of Tim going to the USA.

Pokerchips/Lambo222

Cheer up you two miseries! You don't know the news if you don't know the latest news. DYOR, as they say.
You never know, better days may lie ahead.

CAR3Y

Read my post more carefully.
I said that I had - on Lambo's advice - emailed Lisa who is on the IMM BOD and is responsible for investor relations.
Ask her about Tim's trip to the USA.
And I suggest that Lambo follows his own advice and emails Lisa for the latest info instead of relying on Tim's interview of over a month ago.

Lambo222.

Thanks for your advice to email Lisa.
I did.
The news from her is diametrically opposite to your picture of Tim in America.
I suggest that everyone who wants to know the truth should email Lisa as I did.

Lambo222:

What makes you so sure that the CEO is visiting Avion this week? I thought that in his interview on Proactive last month all he said was that he would visit Avion "next month" ie November. So he could delay his visit until the last day/week of this month depending on when there is anything to report on the progress of the PK Study.

Nolupus
Cod-cryptic as ever.

Nolupus:

I noted your comment "so much deramping puts me in a buying mode".
I was disinclined to take you seriously until these late buys today of 250K and 150K. Congratulations on your boldness!

ILS.
"Takeover or something" - you must be joking.
The amounts of money involved are miniscule and sells still outstrip buys in the past 2 days.

Pokerchips:

Thanks, PC, for the pat on the head and the advice to wait for Big Daddy to tell us that all will be well!

Pokerchips:

Thanks for your comments this afternoon. They have clarified some of the financial and investment issues that have been troubling me.
I would feel more assured if the confident tone adopted by Tim McC in his two recent Proactive interviews were supported by concrete evidence of progress in both the PK Lupuzor study and the research programmes being conducted by IMM's subsidiary in France.
In both of these interviews (17 August and 4 October) he says confidently that the market will be updated on the progress of the PK study but neither in these interviews nor in RNS notifications has there been any detail provided on progress. Eg: has recruitment of the 24 healthy male volunteers started? How many volunteers have been recruited? Over how long a period will they receive doses of Lupuzor? How much longer will it be to achieve completion of the PK study?
How will success be measured?
Tim McC said the study would take 8 weeks but to allow 12 weeks for "wriggle room". Unfortunately, none of us know when the study officially started so none has a clue as to when it will finish.
I'm afraid it stinks but it is unfortunately so typical of what we have had to endure since the failure of the first Lupuzor Phase 3 trial in May 2018.

Pokerchips:
Thanks for your analysis of the current financial situation of IMM.
If you are correct, the cash outlay for Admin and R and D in H2 of 2021 will be £2-.0 - 2.2m while the cash in hand is £1.6m, leaving a cash shortfall of £0.4- 0.6 mill. at year end.
3 ways in which this can be covered: Cut costs; borrow; raise more equity. Or sell the company/declare bankruptcy.
A non-cash gain via eg an increase in the valuation of Incanthera shares will not suffice.
Is this correct?

Pokerchips:
Thanks for your analysis of the current financial situation of IMM.
If you are correct, the cash outlay for Admin and R and D in H2 of 2021 will be £2-.0 - 2.2m while the cash in hand is £1.6m, leaving a cash shortfall of £0.4- 0.6 mill. at year end.
3 ways in which this can be covered: Cut costs; borrow; raise more equity. Or sell the company/declare bankruptcy.
A non-cash gain via eg an increase in the valuation of Incanthera shares will not suffice.
Is this correct?

Dallo.
I missed Tim's remark in his latest Proactive interview about a possible surprise from left field that would please investors when I listened first time around. But after your alert I listened once more and sure enough he slipped it in very quietly about 30 secs from the end of the interview. I wonder what he was alluding to. I'm not holding my breath having been let down so often before. Still, worth waiting a little longer to see if anything to our benefit pops up.

Pokerchips:
Thanks for the info on Sol. I note the date of the announcement - 27 Sept 2021 - so very current news. These negotiations proceed very slowly.
By the way, Tim McC said being CEO of IMM would be a full time job. Has he therefore given up his Chairmanship of Incanthera?