Member Info for bald_eagle

"I've had a reply from Antoinette at FUM so will keep going with my query"
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What did she say?.....what was your question?

Which is more likely between now & September, 12p or 20p?

Given that there is the possibility that FUM have some sort of fund raising announced in September. By then they may/should have an idea of the FDA trial and how much money they will need. To delay the FDA trial is an option but it's not really a good option because the US market is so important...it would also be putting most of their 'eggs' in the EMA basket, which could take longer than expected.

I suppose there could be another concerted effort by daytraders to drive the SP higher...but it would be risky for them because FUM have a habit of clutching defeat from the jaws of victory. And a fundraising is one such hazard that is almost inevitable at some point (IMO).

PS slightly irrational comments from some usually sensible people that negative or positive comments on a discussion board can move the SP up or down. Although obviously everyone hangs on the words of 'the Eagle' much like I am the UK version of Warren Buffet. The Eagle has spoken...watch the SP fall like a stone.

I never look at 'sure things' promoted by people who pop up from nowhere. It seems like everyone else on here is of the same opinion. So why do people do it....generosity of spirit? Unlikely

Or perhaps..FUM has had some sort of day trading 'event' and he wants to coral the troops - a bit more free ammunition- on another attack/target. Look at the chart...2 years stuck on 30p and by pure coincidence he/she pops up here with a 'sure thing'. Amanda has fallen in love, with the Yesman!! The Joker isn't going to take being the jilted lover lying down!

On next weeks episode of 'Fantasy Island frolics' Amanda has Yesman's love child and the 'Joker' marries a goat.

DrS, you don't know me from Adam. But like everyone here I wish you all the best in your future endeavours. In times like these we are all being forced to make impossible choices but ultimately we have to do what has to be done, to keep our families together.

I sense you have a positive attitude to life and it will provide good foundations for whatever you do.

BagoChips, you've just described a gimmick. Sure the 'gimmick' might attract some people in search of a quick buck. But one cannot base a profitable long term business on a gimmick...the product has to do what is promised 'on the tin'.
People might buy it once 'for a laugh' but if it don't deliver then they won't touch it again....like pyramid schemes by the time the average investor realises that the business is founded on a gimmick the 'clever' people will be long gone (clever = people in the know).

PS I'm not saying that FUM products are gimmicks...but there are signs and there is a risk.

- CSD500 disappeared after much hype.
- PET500 disappeared without trace
- MED2002/2005 after much hype were found to be pointless

And the base formulation of Dermasys (MED3000 former placebo) isn't patented yet. They recently applied for the patent...but it's currently 'patent pending'.

All the patents they have on MED2002/MED2005 & CSD500 & PET500 are mostly worthless...no matter what FUM say on their website.

The patents are on the 'formulation' for each product. If they discontinue the product then the patent is pointless. SO the most they can honestly say about Dermasys is that the name is trademarked and patent is pending on MED3000.

But we don't really know how MED3000 actually works (there is some evapouration/cooling theory), but we don't know if the 'mode of action' is patentable. The patent application for MED3000 is for the formulation....the base Dermasys formulation (without any active ingredient).

Don't tell me that MED3000 is also a cure for baldness...sign me up for 300 gallons of the stuff. Stiff, thick lustrous hair...my sort of Fantasy island.

The Eagle can dream!!

Money was forecast to last until Q2 2021 (according to ANgela). The cost of the FDA trIAl may not be too much...because the 'least burdensome' approach may allow for a very limited trIAl. But it will require money and that moves the prospect of some form of fundraising nearer than Q2 2021. So the question is can FUM secure additional funds from another source and if they cannot when will the fundraising (share placing I presume) take place...sooner or later. Delaying into next year is bound to weigh heavy on the SP for the next 6-12 months, because investors know that a fund raising is coming down the tracks. They will presumably also need the funds fairly soon to get the trIAL started...unless they delay it until the EMA have spoken.

We may get an answer in September...I expect FUM are in contact with their big institutional investors right now. 4 weeks or so isn't long to wait.

It's T R I A L

Yesman, it's TRIAL....trial...T_R_I_A_L...trIAl...trial!!

And 3m what's? You could mean £3 million....but I suppose it could be a suggestion to boil asparagus for 3 minutes when trail biking in the Pyrenees.

The FM57 results also seem a little odd. One would expect that as ED severity increases the effectiveness of the treatment would reduce...this wasn't seen in the FM57 trial. The strongest response was observed in Severe ED sufferers and the weakest was in the moderate group. Very strange.

Of course because we don't have the results for a 'real' placebo to compare against it does leave unanswered questions. Perhaps this is what the additional FDA trial will answer.

PS Ken James did attempt to do a desktop study comparing the placebo effect in other ED studies (see webcast from 1st April 2020, at approx 20 mins) and comparing it to the FM57 trial...however those used oral placebo's (which may or may not be a relevant comparision). There is nothing like having a sexy nurse rub on a gel to enervate the glands!!

PPS https://futuramedical.com/investor-centre/videos-and-webcasts/webcasts/

Did I not say that big pharma would have experts who would go through FUM's data with a fine toothcomb when negotiating potential deals with Mr Barder and find weaknesses in the FUM story...and what do we have, our very own 'expert' who in a matter of a day of part time analysis has identified potential 'problems' with the MED3000 data. If the King of the Ithacanese can do it during coffee breaks then imagine what a team of hard nosed forensic scientific experts could do full time. Slightly scary. But Mr Barder is the master dealmaker...he got Trumps deal making book last Christmas and he has read every page twice!!...apparently.

Bucolic, I'm not sure if you are 100% correct. I agree that MED3000 wasn't the subject under test in FM57 trial (indeed it didn't exist at the time...it was the 'placebo'). But the data collected for the 'placebo' is still valid data. The question is, will regulators require MED3000 to be trialled against a real placebo? Possibly not, because MED3000 doesn't contain an active ingredient as such. ALthough I don't know enough about the FDA & EMA requirements to comment really.

Based on the limited additional trial the FDA are asking for (according to Ken James) it would seem they aren't asking for a new P3 trial with MED3000 as the subject. Of course any claims that FUM make about MED3000 have to be backed up by test data...but the regulatory hurdles are bound to be less simply because MED3000 is a medical device.

" The EMA and FDA, from my experience, are in synch in their decisions about 7/8 times out of 10."
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Odysseus, what does that mean in practice? Are you suggesting that there is a 70-80% chance of EMA asking for similar data to that being requested by the FDA? You would have to know both systems fairly well to make such a judgement. Or is it a gut feeling...that the risk is quite high that EMA wants additional information, thus delaying the approval process?

If EMA does come back asking for more information then a pharma deal seems unlikely this year and the need for a fundraising becomes 'almost' certain (IMO).

But I suppose FUM might pull a rabbit or two out of the hat in the September results. I'm sure Ken will cook up something to keep us interested....perhaps the announcement that Dermasys is going to be used to administer the Oxford Covid-19 vaccine!!

"I asked a question , I DID NOT MAKE A STATEMENT."
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Arthur, I never said you 'made a statement'...just a 'suggestion' (in the form of a question) e.g. "Isn't Mr Barder a master dealmaker?". Is that a question, suggestion or both?!

Your 'question' btw was: "With the World’s leading Pharmas trying to find a vaccine to combat the Coronavirus could the DermaSys delivery system be used if the molecular make -up of the vaccine was small enough ?"
(I know, I know....it wasn't you, some numptie hacked your account and wrote some utter nonsense in your name...those darned Russians!!!)
"TOO MUCH HOT AIR HAS GOT YOU FRAYING AROUND THE EDGES."
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Arthur, personally - being an Eagle - I cannot get 'too much hot air'. It allows me to soar high in the sky.

"Clearly you aren’t aware that in Spain del dia is a Daly menu - alright Squire ?"
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Arthur, we aren't allowed to talk about Spain 'apparently', even if you're being ironic ('the Joker' don't like it).

PS Don't you mean 'menu del dia'?...similar to 'Plat du jour' no doubt.

"What was different about Dermasys in this trial, if anything? That's the question I'll try to get answered."
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Volatility, good luck with that. I doudt you will get much of an answer beyond..."We cannot divulge market sensitive information" (or some other claptrap)

FUM management will view it as water under the bridge. THey won't won't to dwell on past mistakes.

"patented technology DermaSys is designed to deliver clinically proven effective medical treatments via the skin...."
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Warrenbe, Dermasys (renamed MED3000) isn't itself patented....they recently applied for the patent for the base 'dermaysy' formulation, so effectively patent is pending.

Also Dermasys was 'designed' to take an active ingredient through the skin...it was designed as a drug delivery system. However MED3000 has been shown to have an effect on ED patients....they have a theory how it works but I don't believe they have provided any proof on how it works. Currently they have a theory...I like to believe it's Magic fairy dust that puts lead in your pencil.

Patent pending!!

"Sorry to disappoint you Old Bird..."
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Arthur, how strange...then it looks like someone hacked your account and wrote the following:

"Corvid-19 and transdermal DermaSys.
8 Mar '20
With the World’s leading Pharmas trying to find a vaccine to combat the Coronavirus could the
DermaSys delivery system be used if the molecular make -up of the vaccine was small enough ?"

[https://www.lse.co.uk/ShareChat.asp?ShareTicker=FUM&share=Futura-Medical&page=68]

PS: My Google translation for 'arturo del dia' comes back with 'Arthur of the day'. So you will have to take this up with Google, Arthur!!

100% Mr consistent....FUM isn't for widows & orphans.

Arthur, weren't you the bloke who suggested using Dermasys to get the Covid-19 vaccine through the skin (when it becomes available)?

It did make me laugh...still does.
Ooops!!...Goldilocks will probably jump on that fantasy bandwagon now.

Volatility, I agree I cannot find anything that says that the P2 trial used Dermasys as the placebo...indeed the nature of the placebo was not mentioned (other than being a gel). I always understood it to be Dermasys but I may have got that from the P3 trial (which we obviously know it was).

PS: P3 trial (FM57) was described in FUM's RNS as: "FM57 is a dose-ranging, multi-centre, randomised, double-blind, placebo-controlled, home use, parallel group clinical trial of topically applied GTN and will recruit approximately 1,000 patients with mild, moderate or severe ED and compare the efficacy of 0.2%, 0.4% and 0.6% GTN doses of MED2002 against that of placebo. "

And of course we know that the 'placebo' used in FM57 was definitely Dermasys (since renamed MED3000). They may have changed the placebo from P2 (FM53) to P3 (FM57) but it is difficult to see why.

The FDA have asked for another trial...I'm not entirely sure why, efficacy data for slightly longer that P3 provided.

The EMA may or may not ask for additional testing and/or data. Apparently it may take up t 6 months to give their response to the recent application. I would hope that if they do need additional information they will let FUM know ASAP and not keep them (& investors) waiting unnecessarily.