Member Info for AquaeSulis01

Well Phat and Ted perhaps you ought to meet somewhere in the middle and invest in Seed Health then, because their DS-01 product contains both LPLDL and lactobacillus rhamnoses (the lysate used in skinbio's anti-ageing cream) so you'll end up sorting out both your IBS and look younger doing it!

Thanks for your opinion Phat but you do talk a load of Biotix at times. Just because you feel Skin offers more potential (which is currently priced in pre trial results and confirmed sales) does not mean Opti whose sp does not represent its current revenue generation and asset value, is a sale.

Probably a wise move Stoater. Whilst the Clinical Trial results are yet to be published for Seed's DS-01 which contains LPLDL, it seems to be flying off the shelf (sold out currently) and received a very favourable write-up from the US Melmagazine correspondent.

https://my.seed.com/daily-synbiotic

https://melmagazine.com/en-us/story/i-took-a-pill-to-hack-my-poop-and-now-im-king-of-the-bathroom

https://seed.com/male-daily-synbiotic/?sscid=41k5_63ynj

Short podcast out
https://twitter.com/PowerMetRes/status/1379750247090556939?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet

Also the significance of this statement from the RNS is illustrated in the link below "Importantly, concurrent surface mapping has identified small scale nickel-copper-magnetite gossanous veins at a new outcrop at Mihanza Hill. The geological team consider this discovery substantiates the potential for primary nickel rich sulphide mineralisation within the underlying ultramafic body, underpinning the requirement to progress to a deeper drilling programme."

https://www.sciencedirect.com/topics/earth-and-planetary-sciences/gossan

Gossans are signboards that point to what lies beneath the surface” – Bateman (1950) [4]. Gossans are highly ferruginous rock which is the product of the oxidation by weathering and leaching of a sulfide body. The color is significantly dependent on the mineralogical composition of the iron hydroxides and oxides phases and varies between reddish (hematite), yellow (jarosite), brown, black with stains of azure blue, malachite green and pea**** color (copper).

Should have included this link

https://www.spglobal.com/marketintelligence/en/news-insights/latest-news-headlines/japan-keeps-auto-industry-s-hydrogen-dreams-alive-62160857

chilting, re cars agree re the Western World in the short term, but a different picture in Asia led by Japan and South Korea who recognise the raw material threat posed by China and hence are investing aggressively in hydrogen infrastructure. Now having seen how Japan revolutionised the World Motor Cycle industry in the 1970s I would not bet against that re-occurring for hydrogen cars

The 12 week phase 2 Clinical Trial for Seed Health's DS01 containing LPLDL announced 02nd Oct 2020 should have concluded by now or at least nears completion. Seed was using an app owned by Auggi (subsequently acquired) to monitor the progress of individuals on the trial by analysing photos of their stools.

https://www.fiercehealthcare.com/tech/to-many-it-s-just-a-waste-but-seed-health-sees-it-as-next-thing-health-tracking-it-bought-ai
https://www.auggi.ai

22 Mar 2021 --- North American nutrition bar and functional powder specialist Nellson is releasing a white paper detailing its findings on the nutrition bar snack category’s latest developments.
The paper highlights the importance of protein sourcing, sugar and fiber content and other functional ingredients.
he sugar challenge
Last year, the US Food and Drug Administration (FDA) introduced new labeling challenges that significantly affect the nutrition bar market.

Nutrition facts panels must now indicate the amount of added sugars and total sugars. Furthermore, brands can only count dietary fiber from particular sources.

In terms of sugar content, Nellson notes formulators are trying to reduce both naturally occurring sugars (such as those in fruit chunks) and added sugars.

This presents challenges, however. Sugar syrups bring essential functionality to nutrition bars by binding proteins and other inclusions and helping bars retain softness and pliability.

“Removing the binding syrup entirely, as some keto-friendly bar products have done, requires tight manufacturing control to maintain product integrity.

Other manufacturers have tried replacing sugar syrups with sugar alcohol like maltitol, which helps binding but has potential gastrointestinal side effects.

Using fiber syrups is another alternative but can be very drying without sophisticated formula optimization.

Allulose, a rare sugar that’s not metabolized by the body, is not counted in added or total sugars. In concert with other binders, it has “superb potential as a sugar reducer,” says Nellson. Its approval is still pending in some countries.

Fiber challenge
Problems with fiber formulation are also tricky, notes Nellson. Under the new FDA regulations, carbohydrates may only be declared as fiber if they are “intact, naturally occurring as a plant ingredient, or deemed to provide positive physiological benefits to human health.”

This poses many reformulation headaches, concedes the company.

For example, a common binder in low-carb bars – isomalto-oligosaccharides (IMO) – was not approved as a fiber source by the FDA.

Fiber content consequently dropped after the ruling, while sugars and carbohydrates went through the roof. Now, brands leveraging this ingredient are scrambling for other fiber sources or sugar alcohol syrups to bring their net carbs back down
https://www.nutritioninsight.com/news/whats-next-in-nutrition-bars-nellson-highlights-sugar-protein-and-fiber-trends.html

Better find a way to address the raw materials issue then!
https://www.telegraph.co.uk/business/2021/04/02/race-heavy-metal-puts-electric-car-revolution-risk2/
Race for heavy metals puts electric car revolution at risk
Raw materials are vital to the green technology revolution, but China's insatiable thirst could leave Britain in its dust cloud
The mining giant China Molybenedum planted its flag in the Democratic Republic of Congo’s prized 350km copper belt four years ago, paying $2.6bn (£2bn) for the Tenke Fungurume mine from Freeport McMoran.
It expanded its empire in December, paying another $550m for Freeport’s nearby Kisanfu mine, giving it access to further 6.3m tonnes of copper and 3.1m tonnes of cobalt.
Chinese companies now dominate mining in the central African country that produces 70pc of the world’s cobalt – a trend eyed warily around the world as others wake up to their own growing needs.
As economies including the UK’s try to reduce their reliance on fossil fuels, the thirst for other natural resources continues to grow.
Batteries that power electric cars need cobalt and lithium, as do batteries that store power on windy and sunny days. Magnets in wind turbines need neodymium and dysprosium. Solar panels need tellurium, among other examples.
The World Bank estimates 3bn tonnes of minerals will be needed in the overhaul to meet Paris climate agreement targets by 2050, with a five-fold increase in demand for some products, notes a new report by KPMG.
It is thought there is enough of the materials available in the ground to go around. But mines take time and money to develop. And many materials are concentrated in certain countries such as China, Russia, and the DRC.
Supply constraints and price spikes, threatening the shift to greener technologies and disruption to businesses, are on the horizon without intervention to develop supply chains, experts are warning.
“The supply of clean energy depends on mined natural resources, which are steeped in geological, geopolitical and governance challenges,” says KPMG in its report published yesterday.
“The very beginning of that supply chain – the sourcing of metals, minerals and resources could turn out to be the weakest link.”
UK politicians have since embraced green technology that will intensify demand for those materials, banning the sale of new combustion engines by 2030 and planning a four-fold increase in wind power, as they try to cut carbon emissions to net zero by 2050.
It is hoped many of those wind turbines and batteries will be made in the UK. That will require a lot of raw materials. The Faraday Institution estimates that the UK will need 14,000 tonnes of cobalt, 75,000 tonnes of lithium and 86,000 tonnes of nickel to produce 92Gwh of electric vehicle batteries in 2035. That compares to below 2,000 tonnes used today.

Augers well for the DRC Kisinka project where a 25 year exploration licence has been applied for following the size and scale of the copper and cobalt anomaly confirmed to date through exploration.

https://www.telegraph.co.uk/business/2021/04/02/race-heavy-metal-puts-electric-car-revolution-risk2/
Race for heavy metals puts electric car revolution at risk
Raw materials are vital to the green technology revolution, but China's insatiable thirst could leave Britain in its dust cloud
The mining giant China Molybenedum planted its flag in the Democratic Republic of Congo’s prized 350km copper belt four years ago, paying $2.6bn (£2bn) for the Tenke Fungurume mine from Freeport McMoran.
It expanded its empire in December, paying another $550m for Freeport’s nearby Kisanfu mine, giving it access to further 6.3m tonnes of copper and 3.1m tonnes of cobalt.
Chinese companies now dominate mining in the central African country that produces 70pc of the world’s cobalt – a trend eyed warily around the world as others wake up to their own growing needs.
As economies including the UK’s try to reduce their reliance on fossil fuels, the thirst for other natural resources continues to grow.
Batteries that power electric cars need cobalt and lithium, as do batteries that store power on windy and sunny days. Magnets in wind turbines need neodymium and dysprosium. Solar panels need tellurium, among other examples.
The World Bank estimates 3bn tonnes of minerals will be needed in the overhaul to meet Paris climate agreement targets by 2050, with a five-fold increase in demand for some products, notes a new report by KPMG.
It is thought there is enough of the materials available in the ground to go around. But mines take time and money to develop. And many materials are concentrated in certain countries such as China, Russia, and the DRC.
Supply constraints and price spikes, threatening the shift to greener technologies and disruption to businesses, are on the horizon without intervention to develop supply chains, experts are warning.
“The supply of clean energy depends on mined natural resources, which are steeped in geological, geopolitical and governance challenges,” says KPMG in its report published yesterday.
“The very beginning of that supply chain – the sourcing of metals, minerals and resources could turn out to be the weakest link.”
UK politicians have since embraced green technology that will intensify demand for those materials, banning the sale of new combustion engines by 2030 and planning a four-fold increase in wind power, as they try to cut carbon emissions to net zero by 2050.
It is hoped many of those wind turbines and batteries will be made in the UK. That will require a lot of raw materials. The Faraday Institution estimates that the UK will need 14,000 tonnes of cobalt, 75,000 tonnes of lithium and 86,000 tonnes of nickel to produce 92Gwh of electric vehicle batteries in 2035. That compares to below 2,000 tonnes used today.

A certain A bell believes the new company once launched will exceed the value of both RRR and Pow

Red Rock Resources get set for busy year of ... - YouTube

belgrano,
You keep using the word cure for psoriasis when there is no cure; it is a treatment that appears to be alleviating the symptoms even for severe sufferers which is great, but does mean it needs to be taken for ever more, which is also great for company profits.

Also, the product axisbiotix is a food supplement taken orally and made up of 6 live probiotix and is nothing to do with skinbiotix which is a lysate (non-living bacteria) derived from Lactobacillus rhamnoses and used as a skin cream which is what Croda are interested in

In plain English Corby I believe it means there is no Nickel Sulphide present in the third hole
Earlier for the third hole KKME reported that "Coring started from 15.8m. The rock intersected is an apparently monotonous ultramafic, probably a serpentinised dunite. It is much less fractured than the rock in the first two holes. No pyroxenite or obvious harzburgite was seen. The rock is fresh from about 91m."

Serpentinization is a processes whereby rock (usually ultramafic) is changed, with the addition of water into the crystal structure of the minerals found within the rock. A common example is the serpentinization of peridotite (or dunite) into serpentinite (the metamorphic equivalent).
Metamorphic processes usually involve the addition of heat and pressure: a rock is buried, heats up and is squeezed, and the minerals change in an attempt to regain equilibrium with the new environment (like shale to slate, or limestone to marble).
In the case of peridotite to serpentinite, the process actually involves a reduction in heat and pressure. Peridotite starts out as a sub-crustal, upper mantle rock. If tectonic forces move it nearer to the surface, the reduction in T&P cause the minerals (usually olivine and pyroxene) to destabilize and change into the mineral serpentine. No, I'm not mixing up rocks and minerals. Serpentinite is a rock which is composed of the mineral serpentine and formed by a process called serpentinization
The pyroxenes (commonly abbreviated to Px) are a group of important rock-forming inosilicate minerals found in many igneous and metamorphic rocks. Pyroxenes have the general formula XY(Si,Al)2O6, where X represents calcium, sodium, iron (II) or magnesium and more rarely zinc, manganese or lithium, and Y represents ions of smaller size, such as chromium, aluminium, iron (III), magnesium, cobalt, manganese, scandium, titanium, vanadium or even iron (II).

There is an Apr 1 update to the Molopo Farms RNS on the KKME website; key difference is the announced completion of drill hole 3.
https://www.kalaharikey.co.uk/news/
"The third borehole (into Target 1-11a) has been completed at a depth of 502.4m. Preliminary examination of the unsliced core to about 478m indicates a fine-grained black ultramafic rock that is magnetic, and relatively unfractured. There are minor serpentine/talc veins. As far as seen the rock is very uniform and monotonous, and has been from surface. Thus, the core in this borehole is different from rock core from the first two boreholes to indicate that the feeder zone was a conduit through a range of rock types."

France and Germany wrongfoot the UK on hydrogen-fuelled road transport – again
Car-making giant Stellantis will soon have a production fuel cell vehicle on sale in the UK, but how does that fit with Government policy?
IN the week when the UK Government grudgingly awarded a minuscule grant into hydrogen fuel cell research, Stellantis, the giant European and American car-making group, has revealed a full production hydrogen fuel-cell van which will go on sale in Europe and the UK this year.

Stellantis, the Peugeot/Citroen/Opel/Fiat conglomerate, also says that it is investigating using a similar hybridised fuel-cell system in a passenger car, which it will put into production in the near future.

“We are currently looking at ramping up the project,” she continued, “and it makes sense to look at fitting the next generation [of the technology] into passenger cars, which will be the next step.”

The move coincided with an announcement from the French and German transport ministers committing their governments to hydrogen technology and earmarking €7 billion and €5.6 billion respectively into supporting the Stellantis project, improving public demand for fuel cells, developing green hydrogen generation and the provision of a hydrogen refuelling infrastructure in both countries.

France currently has 25 hydrogen filling stations, Germany 90 and the UK 12.
Stellantis claims a refuelling time of only three minutes for its new commercial vehicle. Adding liquefied hydrogen to a car (or van) is remarkably similar to filling with petrol or diesel CREDIT: Ed Robinson
This will be an embarrassment for the UK Government, which has claimed that hydrogen is only suitable for marine, heavy commercial and rail technology and seems dead set on committing the UK’s 33 million road cars and 1.55 million vans to battery-electric technology by a deadline of 2030.

Last year’s Department for Transport’s Decarbonising Road Transport consultation paper didn’t even mention hydrogen fuel cells, and senior civil servants questioned about fuel-cells at the Low Carbon Vehicle Partnership conference last autumn dismissed the technology despite the Government’s national infrastructure board saying that the UK needed to plan for hydrogen.
The new mid-sized fuel cell van, which will at first be badged as a Peugeot Expert, Citroën Dispatch and Opel Vivaro, will only be available as a left-hand drive vehicle this year, but by 2022 it will also come to the UK as a right-hand-drive Vauxhall
https://www.telegraph.co.uk/cars/comment/france-germany-wrongfoot-uk-hydrogen-fuelled-road-transport/?li_source=LI&li_medium=liftigniter-rhr

Contain Stevia

https://energy.economictimes.indiatimes.com/news/renewable/global-energy-climate-leaders-pledge-clean-energy-action-at-the-iea-cop26-net-zero-summit/81824524

Must admit I am struggling to interpret some of the data and sample assay testing selection logic and would appreciate a plain English explanation of the results. possible outcomes and why.

From Jan 11th RNS
Initial geological core-logging by KKME's consulting geologist has identified 4.4 metres of ultramafic rocks with finely disseminated sulphides in angled hole KKME 1-6 at approximately 270m vertical depth.
The deepening of drill hole KKME 1-6 from 547 metres to circa 600-650 metres hole depth is set to commence in the week commencing 11 January 2021.
From 22nd Feb RNS
dentification of additional visible sulphides deeper in hole KKME 1-6 gives further encouraging signals to the prospect of discovering significant mineralisation within the Molopo Farms Complex.
The second diamond drill hole at the MFC Project, KKME 1-6, has been continued from 547m to a final depth of 598 metres in ultramafic rocks. The extra hole depth will provide further core from the geophysical target depth and will assist in further geophysical interpretation.
Logging KKME 1-6 cut core has identified disseminated sulphide mineralisation below 500m drill hole depth, notably in the section marked as a target by the geophysics. This is further to disseminated sulphide mineralisation identified around 308-313m drill hole depth from the initial KKME 1-6 core inspection (announced 11 January 2021).
THE 11th JAN RNS REPORTED A DEPTH 270M NOT 308-313M BUT NO EXPLANATION FOR THIS DSISCREPANCY HAS BEEN PROVIDED
From 30th Mar RNS
Nickel sulphides have been identified in three core samples containing visible sulphide grains taken from the drill hole KKME 1-6 (at Target 1-6). A total four thin sections, from the three core samples, were cut from areas with the most abundant sulphides and textural heterogeneity.
The preliminary study shows that the primary magmatic, pentlandite-bearing, assemblage is present only in sample IMK-05139 (taken from 310m down-hole depth). Two samples (IMK-05149 and IMK-05153) from down-hole depths of 295m and 297m respectively) contain relics of primary pentlandite within predominant secondary nickel sulphides, arsenides and alloys (Heazlewoodite, Shandite, Maucherite, Awaruite, and Breithauptite) that were likely formed under reduced conditions.
WHY TEST TWO SAMPLES OUTSIDE THE VISIBLE SULPHIDE DEPTHS REPORTED RATHER THAN FROM THE VISIBLE SULPHIDES FROM THE BELOW 500M DEPTH?

Augurs well for the Weichai partnership

https://www.globaltimes.cn/page/202103/1219741.shtml
Despite the small size of the market for hydrogen fuel cell-powered vehicles, the Chinese government has voiced support for this sector's growth. According to China's New Energy Vehicle Industry Development Plan (2021-2035), the government will support the commercialization of fuel cell vehicles in areas with favourable conditions.

Good opportunity for our new Non-Exec Director to exploit his contacts

https://www.gov.uk/government/news/new-office-for-health-promotion-to-drive-improvement-of-nations-health