Great Opportunity for investors - Angle PLC and FDA Approval21 Jan 2021 11:27
This company is leading a new technology in cancer detection in the body using blood. Detecting Circulating Tumour Cells
Circulating Tumor Cells and the Parsortix® solution:
Solid tumor cancers, such as breast cancer and prostate cancer, shed cancer cells into the patient’s blood stream.
These are cells are known as Circulating Tumor Cells (CTCs). CTCs are very rare, perhaps representing a single cell in one billion blood cells, and are thus very difficult to isolate. They are, however, extremely valuable cells due to several defining features:
They contain information on the type of disease – which has the potential to inform on “personalized” care decisions and targeted drug therapies
Their presence and quantity has been shown to be indicative of patient prognosis
They are very likely to be the route by which primary (localised) tumors spread around the body so resulting in metastatic disease.
The Parsortix® system from ANGLE is able to capture and harvest CTCs from patient blood. This means that a simple peripheral blood test could be used to provide crucial medical information regarding the fluctuating status of a patient’s disease.
It is widely agreed that such a “liquid biopsy” would have a profound impact in understanding the patient’s current cancer status as well as ensuring the optimum treatment is deployed for that individual patient at that particular time.
Market Size
ANGLE’s ultimate objective is the widespread adoption of the Parsortix® system into scholarly institutions and treatment centers which specialize in the diagnosis and treatment of cancer patients. According to the World Health Organization, there were an estimated 14 million new cancer cases worldwide in 2012, a marked rise on the 12.7 million cases in 2008. In 2012, there were an estimated 32.6 million people living with cancer. (Source: http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx)
The incidence of cancer continues to grow as a result of demographic, lifestyle and environmental factors and it is estimated that one in three people in the UK will get cancer during their lifetime.
There are a wide range of potential applications for harvested CTCs including diagnosis, prognosis, mutational analysis and drug selection, drug development, assessment of treatment effectiveness, and remission monitoring. We estimate that this represents a potential global market for ANGLE’s Parsortix® system worth in excess of £8 billion per annum.
ANGLE’s major focus is on the cancer market. There is also a substantial market available in the field of non-invasive fetal diagnostics, which involves harvesting fetal cells from the pregnant mother and analysing for Down’s Syndrome and many other chromosomal and genetic conditions through a simple blood test.
The presentation which you need to watch: https://youtu.be/dmihuELlhDM
The Parsortix® FDA approval coming Q2 2021 which will unlock the opportunity into a 100 billion US$ market
Cheers, Rich