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Redx Pharma jumps as first data shows 'great potential' for fibrosis candidate

Fri, 30th Nov 2018 10:31

(Sharecast News) - Redx Pharma made gains on Friday after it said that pre-clinical data suggested that its RXC006 drug candidate has "great potential" as a treatment for fibrosis.The drug discovery and development company said the first batch of data on the candidate showed it was "highly effective" in suppressing the Wnt pathway, which inhibits porcupine proteins that are generally believed to cause the lung scarring that is typical of idiopathic pulmonary fibrosis.IPF is a severe and life-threatening chronic lung condition with very poor prognosis and limited treatment options.Jörg Distler, professor of internal medicine at the University of Erlangen-Nuremberg, said: "Wnt pathway inhibition presents a novel and exciting opportunity to treat fibrotic diseases, I truly support the idea of targeting the porcupine enzyme."Trials with the drug have successfully suppressed both liver and kidney fibrosis in animal models and led to a reduction in collagen deposition and severity of pulmonary fibrosis in two mouse models.Richard Armer, chief scientific officer at Redx Pharma, said: "The data suggests that RXC006 has great potential to treat fibrosis in human patients. Redx are progressing RXC006 towards the clinic for the treatment of Idiopathic Pulmonary Fibrosis and plan to initiate first in man clinical trials during 2020."Redx Pharma's shares were up 10.34% at 8.00p at 1102 GMT.
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11 Mar 2020 10:23

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28 Feb 2020 18:47

UPDATE: Redx Pharma To Get GBP26 Million Injection Amid No Yesod Bid

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28 Feb 2020 18:08

No Redx Pharma Takeover As Yesod Opts Not To Make Offer

No Redx Pharma Takeover As Yesod Opts Not To Make Offer

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14 Feb 2020 17:11

UK Regulator Extends Deadline For Possible Redx Pharma Cash Offer

UK Regulator Extends Deadline For Possible Redx Pharma Cash Offer

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28 Jan 2020 14:15

UK Regulator Extends Deadline For Possible Redx Pharma Cash Offer

UK Regulator Extends Deadline For Possible Redx Pharma Cash Offer

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24 Jan 2020 11:51

Moulton Goodies Raises Stake In Redx Pharma To 42% From 18%

Moulton Goodies Raises Stake In Redx Pharma To 42% From 18%

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9 Jan 2020 16:02

Redx Pharma nominates next drug development candidate

(Sharecast News) - Drug discovery and development company Redx Pharma announced the nomination of RXC007 as its next drug development candidate for the treatment of fibrosis on Thursday.

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9 Jan 2020 11:17

Redx Pharma Nominates Another Anti-Fibrosis Drug Candidate

Redx Pharma Nominates Another Anti-Fibrosis Drug Candidate

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31 Dec 2019 10:34

UK WINNERS & LOSERS SUMMARY: Redx Surges On Potential Takeover Offer

UK WINNERS & LOSERS SUMMARY: Redx Surges On Potential Takeover Offer

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31 Dec 2019 09:12

Redx Pharma Shares Soar On Discussions Over Possible Takeover Offer

Redx Pharma Shares Soar On Discussions Over Possible Takeover Offer

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31 Dec 2019 08:51

LONDON MARKET OPEN: Stocks Start Mostly Lower Amid Profit Taking

LONDON MARKET OPEN: Stocks Start Mostly Lower Amid Profit Taking

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19 Nov 2019 12:29

Redx collaboration with MDC awarded Innovate UK funding

(Sharecast News) - Redx Pharma announced on Tuesday that Innovate UK has awarded biomedical catalyst funding to Redx and Medicines Discovery Catapult (MCD).

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19 Nov 2019 11:53

Redx Pharma Secures Funding To Develop Lung Condition Therapies

Redx Pharma Secures Funding To Develop Lung Condition Therapies

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19 Aug 2019 10:22

Redx Pharma Gets Approval To Escalate Dose In RXC004 Study

(Alliance News) - Redx Pharma PLC on Monday said it has successfully completed dosing of the first cohort of patients in its ongoing phase 1/2 study with RXC004.RXC004 is an oral porcupine

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19 Aug 2019 09:43

Redx Pharma gets green light to escalate dose in RXC004 study

(Sharecast News) - Drug discovery and development company Redx Pharma has successfully completed dosing of the first cohort of patients in its ongoing phase 1 and 2 study with 'RXC004', it announced on Monday.

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